A Proprietary Extract Of
Also known as: North American ginseng, Panax quinquefolius, CVT-E002
Overview
CVT-E002 is a proprietary extract derived from the roots of *Panax quinquefolius* (North American ginseng), known for its potential immune-modulating properties. This herbal extract contains poly-furanosyl-pyranosyl-saccharides which contribute to its efficacy in enhancing immune function. It has been primarily explored for use in preventing respiratory infections, particularly upper respiratory tract infections (URTIs). While research is still growing, evidence indicates that CVT-E002 may reduce both the incidence and duration of URTIs, highlighted in various clinical trials. The quality of available studies is varied, with some high-quality randomised controlled trials (RCTs) and others showing methodological inconsistencies. Though several clinical trials support its application, further rigorous studies are warranted to fully understand its efficacy and safety profile.
Benefits
CVT-E002 has exhibited several evidence-backed benefits: 1) It may significantly reduce the incidence of URTIs by 25% and shorten the duration of these infections by approximately 6.2 days as corroborated by a systematic review of 747 participants. 2) In specific studies, it reduced the relative risk and duration of respiratory symptoms by 48% and 55%, respectively, especially noted in older adults. 3) The extract also appears to enhance immune function, stimulating T-helper and natural killer cells. Most evidence comes from studies focused on healthy adults or seniors, and it is generally observed that benefits may take a few weeks of consistent use to manifest. The effect sizes reported highlight the clinical significance of CVT-E002 in supporting immune health.
How it works
CVT-E002 primarily functions through immune modulation, stimulating the production of cytokines such as IL-2 and IFN-γ. This modulation enhances the immune response, potentially making the body less susceptible to infections. While the molecular targets of CVT-E002 remain unclear, existing research suggests that it interacts with immune cells, promoting an augmented immune response. The specific details regarding absorption and bioavailability of the extract have not been definitively characterized, indicating a need for further exploration.
Side effects
Generally, CVT-E002 is considered safe, with minimal side effects reported in clinical trials. Most studies show no significant adverse effects, although common side effects (>5%) were rarely reported. Uncommon (<5%) and rare (<1%) side effects have not been extensively documented in the available literature. However, caution is advised for individuals with specific health conditions, as potential interactions could occur with blood thinners or diabetes medications due to its effects on blood sugar and clotting. Pregnant or breastfeeding women are advised against use due to insufficient safety data. Additionally, individuals with diabetes or those taking anticoagulants should consult healthcare providers prior to initiating supplementation.
Dosage
The minimum effective dose of CVT-E002 is typically around 400 mg per day, with optimal dosages ranging from 400 to 800 mg daily. Doses above 800 mg are generally not recommended without medical supervision, as specific upper limits have not been well-established. To achieve the desired effects, it is best taken consistently over several weeks or months. CVT-E002 is available in common forms like capsules or tablets, though specific absorption factors are not thoroughly studied. Currently, there are no identified required cofactors for enhancing its efficacy.
FAQs
How long does it take to see effects?
Typically several weeks of consistent supplementation are needed to observe effects.
Is CVT-E002 safe to use?
Generally safe, but consult a healthcare provider if you have underlying health conditions.
When should I take CVT-E002?
Take it consistently over several weeks for optimal effects.
What results can I expect from using CVT-E002?
It may help reduce the incidence and duration of upper respiratory tract infections.
Is CVT-E002 a cure for colds?
No, it is not a cure but may help in preventing colds.
Research Sources
- https://www.semanticscholar.org/paper/Efficacy-and-Safety-of-CVT-E002,-a-Proprietary-of-A-Mcelhaney-Simor/648e9c790e9707c35271988c3f86aa147a9eda05 – This study evaluates the efficacy and safety of CVT-E002, indicating its potential in preventing URTI symptoms in influenza-vaccinated adults using rigorous methodology but limited sample size.
- https://www.researchgate.net/publication/336586189_Which_Academic_Search_Systems_are_Suitable_for_Systematic_Reviews_or_Meta-Analyses_Evaluating_Retrieval_Qualities_of_Google_Scholar_PubMed_and_26_other_Resources_OPEN_ACCESS – This paper discusses retrieval qualities of various academic search systems and their relevance to systematic reviews, providing context for research methodologies and analytic frameworks.
- https://onlinelibrary.wiley.com/doi/10.1093/ecam/nep068 – A systematic review summarizing findings across multiple studies found that North American ginseng significantly reduced cold incidence and duration among various populations.
- https://www.ncbi.nlm.nih.gov/books/NBK74094/ – This resource provides a comprehensive overview of herbal product safety assessments, discussing the implications for broader supplement usage and evaluation.
- https://www.researchgate.net/publication/324679600_Systematic_Review_and_Meta-Analysis_of_a_Proprietary_Alpha-Amylase_Inhibitor_from_White_Bean_Phaseolus_vulgaris_L_on_Weight_and_Fat_Loss_in_Humans – This meta-analysis evaluates proprietary supplements for health benefits, presenting similarities and points of concern relevant for understanding herbal efficacy in general.
Supplements Containing A Proprietary Extract Of
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