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Acerola Concentrate Proprietary Blend

Also known as: Malpighia emarginata, Acerola, West Indian cherry, Barbados cherry

Overview

Acerola, scientifically known as *Malpighia emarginata*, is a tropical fruit native to the Americas, celebrated for its exceptionally high vitamin C content and rich profile of phytonutrients. It is commonly used to prevent vitamin C deficiency, support immune function, and as an antioxidant. Acerola contains over 1000 mg of ascorbic acid per 100 g of fruit and is also high in soluble solids. The fruit is used in various forms, including capsules, powders, and juices, making it a versatile ingredient for dietary supplements and functional foods. Research on acerola is moderately mature, with robust data on its composition and in vitro effects, but more high-quality clinical trials are needed to fully understand its potential benefits. Its high vitamin C content makes it a popular choice for those looking to boost their immune system and overall health.

Benefits

Acerola is primarily recognized for its high vitamin C content, with studies showing mean ascorbic acid levels exceeding 1000 mg per 100 g of fruit. Vitamin C is essential for immune function and collagen synthesis. While clinical evidence for vitamin C supplementation is well-established, direct randomized controlled trials (RCTs) on acerola concentrate are limited. In vitro and animal studies suggest potential anti-inflammatory and anticancer effects, but human data are currently lacking. Its high phytonutrient content contributes to its antioxidant capacity. Acerola may particularly benefit individuals at risk of vitamin C deficiency or those seeking antioxidant support. The effects of vitamin C on immune support may be observed within days to weeks, but further research is needed to confirm other potential benefits.

How it works

Acerola's primary mechanism of action is through its high vitamin C (ascorbic acid) content, which acts as a cofactor for enzymes involved in collagen synthesis, neurotransmitter production, and antioxidant defense. It supports immune function, skin health, and overall antioxidant status. Vitamin C scavenges reactive oxygen species (ROS), helping to protect cells from oxidative stress. It also modulates inflammatory cytokines, such as TGF-β1, and supports cellular redox balance. The vitamin C from acerola is bioavailable, but specific pharmacokinetic data on acerola concentrate itself are limited. Its interaction with the body systems is primarily through the established roles of vitamin C in various physiological processes.

Side effects

Acerola is generally recognized as safe (GRAS) when consumed in typical dietary amounts. Common side effects are rare at typical doses, but high doses may cause gastrointestinal upset, including diarrhea and nausea. Uncommon side effects are not well-documented specifically for acerola, but may be similar to those associated with high doses of vitamin C. Rare side effects include the possibility of allergic reactions. There are no significant drug interactions reported, but high doses of vitamin C may affect certain medications, such as chemotherapy drugs and statins. Caution is advised with high-dose vitamin C in individuals with a history of kidney stones or hemochromatosis. While safe for most adults, there is insufficient data on the use of acerola in pregnant or lactating women and children, so caution is advised.

Dosage

A minimum effective dose for acerola concentrate has not been definitively established; however, the recommended daily allowance (RDA) for vitamin C is 90 mg/day for men and 75 mg/day for women. Typical acerola supplements provide between 100 and 500 mg of vitamin C per serving, though higher doses may be used for enhanced antioxidant or immune support. The upper limit for vitamin C intake is 2000 mg/day, and acerola concentrate dosages should be adjusted accordingly. Acerola can be taken with or without food, and dividing doses may improve tolerance at higher intakes. It is available in capsules, powders, and juices, with similar bioavailability across forms. Absorption may be enhanced by co-ingestion with food and inhibited by high iron intake. No specific cofactors are required, but general antioxidant support may benefit from co-ingestion with other phytonutrients.

FAQs

Is acerola safe?

Acerola is safe for most people at typical doses. High doses may cause gastrointestinal upset. Consult a healthcare provider if you have concerns.

When should I take acerola?

Acerola can be taken at any time of day. Taking it with food may reduce the risk of gastrointestinal side effects.

What are the expected benefits of taking acerola?

Acerola can improve vitamin C status and provide potential antioxidant and immune benefits. More research is needed to confirm other effects.

Is acerola a cure-all?

No, acerola is not a cure-all. Benefits beyond vitamin C supplementation are not well-established in humans.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC6098779/ – This review highlights acerola as a rich source of vitamin C and phytonutrients, suggesting its potential for value-added products and waste utilization. It emphasizes the fruit's composition and functional properties, noting its high ascorbic acid content and antioxidant capabilities. The review suggests that acerola could be further explored for its health-promoting benefits.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC10889565/ – This review explores the anti-inflammatory and anticancer effects of acerola in preclinical models. It indicates that acerola shows promise in vitro and in animal studies, but emphasizes the need for human data to confirm these effects. The review suggests that while preclinical results are encouraging, clinical trials are necessary to validate acerola's potential health benefits.
  • https://www.webmd.com/vitamins/ai/ingredientmono-608/acerola – WebMD provides general information on acerola, highlighting its use as a source of vitamin C. It mentions the fruit's traditional uses and potential health benefits, but also notes the importance of consulting healthcare professionals for appropriate use. The information serves as a basic overview of acerola's properties and applications.
  • https://www.scielo.br/j/babt/a/HYCNp6BcVnMfBdLng3yJssC/ – This systematic review examines the genetic diversity of acerola and its impact on fruit quality. It reveals that acerola genotypes vary widely in vitamin C, soluble solids, and acidity, with mean ascorbic acid content exceeding 1000 mg per 100 g of fruit. The review focuses on compositional data, providing insights into the genetic factors influencing acerola's nutritional profile.
  • https://pubmed.ncbi.nlm.nih.gov/38396766/ – This study investigates the potential of using acerola extract to enhance the nutritional value of fermented plant-based products. It focuses on the functional properties of acerola and its ability to improve the overall quality of plant-based foods. The research suggests that acerola extract can be a valuable ingredient for fortifying plant-based products with essential nutrients.

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