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Adaptive Blend

Also known as: Adaptive Blend, Adaptogenic Blend, Multi-Ingredient Dietary Supplement Blend, Proprietary Adaptive Blend

Overview

Adaptive Blend is a commercial term for multi-ingredient dietary supplements designed to enhance the body's ability to adapt to physical and mental stress. These blends typically combine adaptogens (such as Rhodiola and Ashwagandha), proteins, and amino acids. The primary goal is to support muscle mass, strength, recovery, and cognitive function during periods of stress. While individual components like protein and amino acids have a strong evidence base, research on specific proprietary blends is less extensive. These blends aim to synergistically enhance adaptation to stressors, often incorporating protein to augment resistance training outcomes. They are available in various forms, including powders and capsules, and are sourced from plant extracts, protein isolates, and essential amino acids.

Benefits

The primary benefit of Adaptive Blends, largely attributed to their protein and amino acid content, is the augmentation of muscle mass and strength gains during resistance exercise training (RET). Meta-analyses have demonstrated moderate effect sizes for improvements in fat-free mass (FFM) and one-repetition maximum (1RM) strength with protein supplementation. Essential amino acids (EAA) and protein supplements also improve muscle strength and physical function in older adults and clinical populations, with small to moderate effect sizes. Some adaptogenic herbs included in these blends may support stress resilience and cognitive function, although high-quality research specific to these blends is limited. Benefits typically manifest after at least 6 weeks of supplementation combined with resistance training.

How it works

Adaptive Blends work through multiple mechanisms depending on their specific composition. Protein and amino acids stimulate muscle protein synthesis via the mTOR pathway, leading to muscle hypertrophy and strength gains. Adaptogens may modulate the hypothalamic-pituitary-adrenal (HPA) axis and oxidative stress responses, potentially enhancing stress resilience. The musculoskeletal system benefits from increased muscle mass and strength, while the neuroendocrine system experiences modulation of the stress response. Protein and amino acids are generally well-absorbed, with absorption influenced by dose and co-ingestion with other nutrients.

Side effects

Protein and amino acid supplements, common components of Adaptive Blends, are generally safe at recommended doses. Common side effects include mild gastrointestinal discomfort in some individuals. Uncommon side effects (1-5%) may include allergic reactions or intolerance to specific components. Rare side effects (<1%) have not been significantly reported in high-quality studies. Potential drug interactions may occur with medications affecting liver enzymes or hormone levels, particularly with some adaptogens. Contraindications include caution in individuals with kidney disease (due to potential protein overload) or hormone-sensitive conditions (due to some adaptogens). Older adults may require adjusted dosing, and clinical supervision is advised in cases of chronic illness.

Dosage

For protein, a minimum effective dose of ≥1.6 g/kg/day total protein intake is associated with gains in muscle mass during resistance training. Optimal protein supplementation doses are around 20-40 g per serving post-exercise. A maximum safe dose is generally up to 2.0-2.2 g/kg/day protein for healthy adults. Post-exercise ingestion optimizes muscle protein synthesis. Whey protein is rapidly absorbed, while blends may include slower-digesting proteins or amino acids. Co-ingestion with carbohydrates may enhance absorption. Adequate energy intake and resistance training are necessary to realize the benefits.

FAQs

Is Adaptive Blend safe for daily use?

Yes, Adaptive Blends are generally safe for daily use when dosed appropriately and considering individual health status. However, it's important to consult with a healthcare professional before starting any new supplement regimen.

How soon will I see results?

Results typically become noticeable after 6 weeks of consistent use, combined with a regular exercise program. Individual results may vary based on diet, exercise intensity, and overall health.

Can it replace whole food protein?

Adaptive Blends can supplement protein intake but should not fully replace a balanced diet rich in whole food protein sources. A varied diet provides essential nutrients beyond protein.

Are adaptogens effective in these blends?

The effectiveness of adaptogens in these blends is an area of ongoing research. While some studies suggest potential benefits, more high-quality research is needed to confirm their efficacy.

Is it suitable for older adults?

Yes, Adaptive Blends can be suitable for older adults, especially for muscle maintenance. However, it's recommended to seek medical advice to ensure appropriate dosing and safety.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC5867436/ – This systematic review and meta-analysis of 15 RCTs (n=1216) found that protein supplementation significantly increased muscle mass and strength during resistance exercise training (RET). The study indicated that baseline protein intake and dose did not explain the variance in gains, highlighting the consistent benefit of protein supplementation. The review used high-quality Cochrane methods, ensuring a rigorous analysis.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC8978023/ – This systematic review and meta-analysis concluded that increasing daily protein intake supports lean body mass gains. The effect sizes were moderate, and meta-regression accounted for exercise status and age, providing a comprehensive analysis of protein's impact on muscle growth. The study used rigorous statistical methods, enhancing the reliability of its findings.
  • https://onlinelibrary.wiley.com/doi/full/10.1002/cl2.1017 – This study investigates the effects of protein and amino acid supplementation. Further details would be needed to provide a more comprehensive summary.
  • https://www.frontiersin.org/articles/10.3389/fpubh.2020.579556/pdf – This study investigates the effects of protein and amino acid supplementation. Further details would be needed to provide a more comprehensive summary.
  • https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/systematic-review-and-metaanalysis-of-the-effect-of-protein-and-amino-acid-supplements-in-older-adults-with-acute-or-chronic-conditions/83C8288C73D79685854E78D5415B9029 – This systematic review and meta-analysis of 39 RCTs involving older adults with acute or chronic conditions found that protein and EAA supplements improve fat-free mass, muscle strength, and physical function with small to moderate effect sizes. The study used a high-quality, random effects model to account for heterogeneity in populations and interventions, strengthening the validity of its conclusions.

Supplements Containing Adaptive Blend

Adaptiv by doTERRA
60

Adaptiv

doTERRA

Score: 60/100

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