ADILASE Brown lily bulb extract
Also known as: Brown lily bulb extract, Bai He (百合) extract, ADILASE, Lilium brownii extract
Overview
Brown lily bulb extract, often referred to as Bai He extract, is a botanical supplement derived from the bulbs of *Lilium brownii* and related *Lilium* species. Traditionally used in Chinese medicine, it is valued for its potential respiratory support, calming effects, and benefits for sleep. The extract is rich in various bioactive compounds, including steroidal saponins (such as 26-O-glucopyranosyl-furost-5-3,26-diol 3-O-[rhamnopyranosyl-(1→2)]-glucopyranoside), polysaccharides, and antioxidants. It is typically available as water-extracted granules standardized for active ingredients. While it has a long history of traditional use, the scientific research on brown lily bulb extract is still in its early to moderate stages, with most studies being preclinical or focusing on metabolomic profiling. High-quality clinical trials are limited, and no systematic reviews or meta-analyses specifically on ADILASE or brown lily bulb extract have been identified.
Benefits
The primary benefits of brown lily bulb extract are largely based on traditional use and anecdotal reports, as high-quality clinical trials are lacking. Traditionally, it is used for respiratory health, specifically for 'moistening dry lungs,' and for its calming properties, which may aid in sleep improvement. Some in vitro studies have indicated that lily bulb extracts possess antioxidant capacity, suggesting a potential role in combating oxidative stress. However, no randomized controlled trials (RCTs) or meta-analyses have quantified clinical benefits or established effect sizes. Therefore, while traditional use suggests benefits for individuals experiencing lung dryness or sleep disturbances, these claims are not yet substantiated by rigorous scientific evidence. The strength of evidence for all reported benefits is considered low, primarily relying on traditional knowledge and preliminary laboratory findings.
How it works
The mechanism of action for brown lily bulb extract is not fully elucidated but is believed to be primarily linked to its rich content of steroidal saponins, polysaccharides, and antioxidants. These compounds likely contribute to its effects through antioxidant activity and potential modulation of inflammatory pathways. The steroidal saponins may interact with cellular membranes or signaling pathways, while polysaccharides could contribute to immune modulation. The extract is thought to provide support to the respiratory system by potentially soothing irritated tissues and may exert calming effects on the central nervous system. Specific molecular targets and detailed pharmacokinetic data regarding its absorption and bioavailability are currently unknown, requiring further research.
Side effects
Based on available literature and traditional use, brown lily bulb extract appears to have a favorable safety profile with no major safety concerns reported. There are no documented common (>5%), uncommon (1-5%), or rare (<1%) side effects. Furthermore, no specific drug interactions or contraindications have been established. However, due to the limited scientific research, especially in clinical settings, comprehensive safety data is not available. For special populations such as pregnant or lactating women, there is insufficient data to confirm safety, and therefore, caution is advised. While traditional use suggests good tolerability, the absence of documented adverse effects does not equate to proven safety across all populations or in conjunction with all medications. Users should consult a healthcare professional before use, especially if they have underlying health conditions or are taking other medications.
Dosage
The optimal and minimum effective dosages for brown lily bulb extract have not been clinically established due to a lack of rigorous research. Commercial products, such as those from ActiveHerb, may provide dosage recommendations based on traditional use or product standardization. For instance, some extracts are provided as granules where 100g of extract granules are equivalent to 1000g of dried herb. However, these are not standardized clinical dosages. There is no established maximum safe dose, and specific timing considerations for administration are not documented. The extract is typically available as water-extracted granules, standardized for active ingredients. Information regarding absorption factors or required cofactors for efficacy is currently unavailable. Users should adhere to product-specific instructions or consult with a qualified healthcare practitioner for personalized dosage guidance, especially given the absence of comprehensive clinical data.
FAQs
Is ADILASE brown lily bulb extract safe?
Based on traditional use and limited reports, it appears safe with no known adverse effects. However, comprehensive clinical safety data is lacking, especially for specific populations like pregnant or lactating women.
What are the expected benefits of brown lily bulb extract?
Traditional use suggests potential benefits for respiratory support (e.g., moistening dry lungs) and sleep improvement. However, these benefits lack rigorous clinical evidence and are not yet scientifically proven.
How long before effects are seen?
There is no clinical data available to determine the time course for experiencing benefits from brown lily bulb extract. Effects may vary based on individual factors and the specific condition being addressed.
Can it be combined with other supplements?
No known contraindications or interactions with other supplements have been documented. However, due to limited research, it's advisable to consult a healthcare professional before combining it with other supplements or medications.
Research Sources
- https://www.mdpi.com/1420-3049/26/5/1340 – This metabolomic study by Kong et al. (2021) analyzed five *Lilium* species, including *Lilium brownii*, identifying steroidal saponins as key bioactive compounds. The research provides a biochemical foundation for the medicinal properties of lily bulbs but does not include clinical data on efficacy or safety in humans.
- https://www.activeherb.com/extract/baihe – This source provides product information from ActiveHerb regarding their Bai He (lily bulb) extract. It describes the product as standardized water-extracted granules and mentions traditional uses for lung and sleep support, based on anecdotal user reports rather than controlled clinical trials.
- https://www.mdpi.com/2304-8158/13/14/2206 – This study focused on the comparative metabolite and antioxidant profiles of various lily species. It demonstrated variations in antioxidant capacity, supporting the potential antioxidant benefits of lily bulb extracts. This was a laboratory study and did not involve clinical endpoints or human trials.