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Alkalinity Blend Proprietary Blend

Also known as: Alkaline mineral blend, Alkalizing mineral complex, Urine alkalizing supplement, Alkalinity Blend Proprietary Blend

Overview

Alkalinity Blend Proprietary Blends are mixtures typically containing buffering minerals like citrates and carbonates of potassium, sodium, or magnesium, designed to increase urine or systemic alkalinity. These minerals are naturally found in fruits, vegetables, and mineral waters. Primarily used to elevate urine pH for conditions such as uric acid or cystine kidney stones, they are also marketed for general wellness, though evidence for systemic effects remains limited. The blends usually contain citrates or carbonates and may be combined with other alkalizing agents. Research maturity is moderate, with most studies focusing on specific alkalizing agents rather than proprietary blends. Evidence for urine alkalization is robust for individual agents, but verification for proprietary blends is often lacking and not independently verified. These blends are available in various forms, including tablets, powders, and liquids.

Benefits

The primary benefit of Alkalinity Blend Proprietary Blends is increasing urine pH, which can be beneficial for individuals with acidic urine or a history of uric acid or cystine kidney stones. A meta-analysis indicated that alkaline water supplementation, a component of these blends, increased urine pH by a standardized mean difference of 0.66 (95% CI: 0.37–0.95), suggesting a moderate effect. By increasing urine pH, these blends may reduce the risk of uric acid or cystine kidney stones. However, evidence for other systemic benefits, such as improved bone health or muscle function, is limited and inconclusive. The clinical significance of urine pH changes depends on the individual's baseline pH and risk factors. Effects on urine pH can typically be observed within hours to days of supplementation.

How it works

Alkalinity Blend Proprietary Blends work by utilizing buffering agents, such as citrates, which are metabolized into bicarbonate. This process increases both systemic and urinary alkalinity. The primary effect is on renal excretion and urine pH, with systemic effects being limited unless large doses are administered. The bicarbonate affects the renal tubules, influencing bicarbonate reabsorption and excretion. Citrates and carbonates are well-absorbed from the gastrointestinal tract and efficiently metabolized into bicarbonate, facilitating the alkalizing effect.

Side effects

Alkalinity Blend Proprietary Blends are generally safe at recommended doses, with most side effects being mild and gastrointestinal in nature. Common side effects, occurring in more than 5% of users, include mild gastrointestinal upset such as nausea and diarrhea. Uncommon side effects, affecting 1-5% of users, may include electrolyte imbalances, such as hyperkalemia with potassium citrate, particularly in susceptible individuals. Rare side effects, occurring in less than 1% of users, include allergic reactions and severe electrolyte disturbances. These blends may interact with potassium-sparing diuretics or medications affected by pH changes, such as some antibiotics. Contraindications include severe renal impairment and hyperkalemia, especially for potassium-containing blends. Use with caution in individuals with pre-existing kidney disease or electrolyte imbalances.

Dosage

The minimum effective dose varies depending on the specific formulation of the Alkalinity Blend Proprietary Blend. For potassium citrate, typical starting doses range from 10 to 20 mEq per day. Optimal dosage ranges for urine alkalization are generally between 20 and 60 mEq per day, expressed as potassium citrate equivalents. The maximum safe dose depends on the mineral content, but potassium citrate should not exceed 100 mEq per day without medical supervision. These supplements can be taken with meals to reduce gastrointestinal upset. They are available in tablets, powders, and liquids, with similar absorption across forms. Food may enhance tolerance. Adequate hydration is recommended when taking these blends.

FAQs

How quickly will I notice changes in urine pH?

Most users will observe changes in urine pH within a few days of starting supplementation. However, the effects on systemic pH are typically minimal.

Is Alkalinity Blend safe for everyone?

It is generally safe for most adults at recommended doses. However, it's important to monitor for any gastrointestinal or electrolyte side effects.

When is the best time to take Alkalinity Blend?

It is best taken with meals to minimize the risk of stomach upset. Consistent timing can also help maintain stable urine pH levels.

What are the expected results from taking Alkalinity Blend?

The primary expected result is an increase in urine pH, which can help reduce the risk of certain types of kidney stones.

Does Alkalinity Blend significantly alter blood pH?

No, it primarily affects urine pH and does not significantly alter blood pH or provide broad systemic health benefits.

Research Sources

https://tau.amegroups.org/article/view/95422/html – This meta-analysis examined the effects of alkaline water supplementation on urine pH. The study found that alkaline water supplementation increased urine pH with a standardized mean difference of 0.66 (95% CI: 0.37–0.95), indicating a moderate effect. Baseline urine pH was predictive of the response to supplementation.
https://www.medsci.org/v19p1290.htm – This article discusses the therapeutic use of potassium citrate in managing uric acid and cystine kidney stones. It highlights that potassium citrate effectively increases urine pH, which reduces the risk of stone formation and recurrence. The study underscores the importance of maintaining adequate urine alkalinity for individuals prone to these types of kidney stones.
https://www.extension.purdue.edu/extmedia/ho/ho-242-w.pdf – This Purdue University Extension article provides general information on water quality and its impact on health. While not directly related to alkalinity blends, it offers context on the importance of water pH and mineral content for overall well-being. It serves as a background resource for understanding the role of alkalinity in dietary considerations.
https://www.healthline.com/nutrition/athletic-greens-review – This is a review of Athletic Greens, a popular supplement. While not directly focused on alkalinity blends, it provides insights into the composition and potential benefits of similar multi-ingredient supplements. It offers a perspective on how such blends are marketed and perceived by consumers.
https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2021.705475/full – This research article explores the chemical properties and potential health impacts of alkaline water. It discusses the mechanisms by which alkaline water can influence body pH and its potential benefits for various health conditions. The study provides a scientific basis for understanding the effects of alkalinity on the body.