ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Aloe Vera Concentrate

Also known as: Aloe vera, Aloe gel, Aloe juice, Aloe barbadensis

Overview

Aloe vera, scientifically known as *Aloe barbadensis*, is a succulent plant native to Africa, widely recognized and utilized for its medicinal properties attributed to its gel and latex. The gel, primarily applied for skin care, is renowned for its anti-inflammatory, antioxidant, and moisturizing properties. It is commonly used topically to manage skin conditions such as burns and wounds, and orally for digestive health and blood sugar control. Despite a growing body of research, the quality of evidence surrounding Aloe vera's efficacy remains variable, as many studies report small sample sizes and methodological limitations. Overall, Aloe vera is a popular herbal supplement with diverse applications in both topical and oral forms.

Benefits

Aloe vera has demonstrated several evidence-based benefits, particularly for diabetic patients and individuals undergoing chemotherapy. Oral administration of Aloe vera may aid in lowering blood glucose levels, proven effective in diabetic individuals. Additionally, topical application significantly reduces the incidence of second and third-degree chemotherapy-induced phlebitis, with a notable odds ratio of 0.10. While some evidence suggests potential benefits for wound healing and skin conditions like psoriasis and genital herpes, these findings are mixed, warranting further research for conclusive results. Benefits typically manifest within days to weeks, varying based on the specific condition treated.

How it works

Aloe vera's beneficial effects are primarily driven by its anti-inflammatory, antioxidant, and immunomodulatory properties. Its bioactive compounds interact with inflammatory mediators and antioxidant pathways, effectively reducing inflammation and oxidative stress. The plant has a direct impact on the skin, digestive system, and circulatory system, showcasing its versatility in promoting health. Topically, Aloe vera is readily absorbed, whereas the absorption of orally ingested forms can differ significantly based on product formulation.

Side effects

Aloe vera is generally considered safe for most users when utilized appropriately. Common side effects, occurring in more than 5% of users, include gastrointestinal upset following oral intake. Uncommon side effects, observed in 1-5% of cases, may consist of allergic reactions, particularly with topical application, while rare incidences (<1%) of severe allergic reactions have been reported. Caution is advised when combined with diabetes medications and blood thinners due to potential drug interactions. Additionally, Aloe vera is contraindicated during pregnancy and breastfeeding due to a lack of safety data. Individuals with known allergies or sensitive skin should exercise caution.

Dosage

The recommended dosage of Aloe vera varies depending on its application. For blood glucose control, studies have utilized doses around 300-500 mg per day. Optimal oral dosages typically range from 300 to 1000 mg daily, while topical applications can be administered as needed. There are limitations to established maximum safe doses, with caution suggested for use beyond 1000 mg daily. For oral consumption, products are generally taken before meals, while topical applications are used at the discretion of the user. Bioavailability may vary based on formulation and individual factors, but cofactor requirements remain unspecified.

FAQs

Is Aloe vera safe for everyone?

Aloe vera is generally safe but should be avoided during pregnancy and breastfeeding. Individuals with allergies or sensitive skin should be cautious.

How should I take Aloe vera?

Aloe vera can be consumed orally or applied topically. For oral use, take it before meals; topical use can be as needed.

What can I expect from Aloe vera treatment?

Results vary based on the condition being treated. Benefits may appear within days to weeks.

Can Aloe vera interact with medications?

Yes, Aloe vera may interact with diabetes medications and blood thinners, so consult a healthcare professional.

Is Aloe vera a cure for all ailments?

No, Aloe vera provides condition-specific benefits and is not a universal remedy.

Research Sources

  • https://pubmed.ncbi.nlm.nih.gov/32924222/ – This umbrella review highlights the potential of Aloe vera in preventing chemotherapy-induced phlebitis and lowering blood glucose. Most evidence is categorized as weak due to small sample sizes and varying methodological quality.
  • https://pubmed.ncbi.nlm.nih.gov/10885091/ – A systematic review of ten clinical trials examines Aloe vera's effectiveness in lowering blood glucose and lipid levels, as well as its potential in treating genital herpes and psoriasis. The study emphasizes the limitations in quality and quantity of research available.
  • https://e-century.us/files/ijcem/9/6/ijcem0023233.pdf – A meta-analysis involving 4530 patients indicates that Aloe vera significantly decreases the incidence of chemotherapy-induced phlebitis. It notes potential publication bias but affirms the high quality of findings due to large sample size.

Supplements Containing Aloe Vera Concentrate

Elimi-Tox PM Cleansing Formula by Bronson Laboratories
70

Elimi-Tox PM Cleansing Formula

Bronson Laboratories

Score: 70/100
Cell Activator by Herbalife
68

Cell Activator

Herbalife

Score: 68/100
Herbal Aloe Concentrate Mango Flavor by Herbalife
58

Herbal Aloe Concentrate Mango Flavor

Herbalife

Score: 58/100
Ready Herbal Aloe by Herbalife
73

Ready Herbal Aloe

Herbalife

Score: 73/100
Herbal Aloe Concentrate Mango Flavor by Herbalife
75

Herbal Aloe Concentrate Mango Flavor

Herbalife

Score: 75/100
40x Aloe Vera Concentrate by Purium Health Products
63

40x Aloe Vera Concentrate

Purium Health Products

Score: 63/100

Recommended Articles

Milk Thistle & Liver Health: The Role of Silymarin

Milk Thistle & Liver Health: The Role of Silymarin

Silymarin in milk thistle significantly supports liver health by providing antioxidant properties and therapeutic effects on liver diseases.

Boost Brain Health: Key Ingredients for Aging

Boost Brain Health: Key Ingredients for Aging

Omega-3 fatty acids, Vitamin E, and curcumin are key ingredients that support cognitive function in aging, alongside the Mediterranean and MIND diets.

Best Ingredients for Kidney Health & Function

Best Ingredients for Kidney Health & Function

Foods high in antioxidants, omega-3 fatty acids, and following diets like the DASH and Mediterranean are crucial for kidney health.

Mushroom Supplement Extraction: Enhancing Potency

Mushroom Supplement Extraction: Enhancing Potency

Extraction is essential to unlock the full potency of certain mushroom supplements like Reishi, Cordyceps, and Lion's Mane.