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Aminofx

Also known as: Branched-Chain Amino Acids (BCAAs), Essential Amino Acids (EAAs), Amino acid supplements, Amino Acids

Overview

Amino acid supplements are derived from protein-rich sources such as meat, fish, eggs, dairy, legumes, and nuts. They are primarily utilized by athletes and bodybuilders to enhance muscle recovery, growth, and performance. These supplements typically contain branched-chain amino acids (BCAAs) like leucine, isoleucine, and valine, as well as essential amino acids. Their effectiveness in improving muscle strength and recovery is supported by significant evidence, including systematic reviews and meta-analyses, making them a crucial component of sports nutrition. Amino acids stimulate muscle protein synthesis through the mTOR pathway, driving various physiological changes that support physical activity and recovery. They can be found in various forms, including powders, capsules, and liquids.

Benefits

Evidence-based benefits of amino acid supplementation include significant increases in muscle strength and mass, particularly during resistance training, with studies showing a mean difference of 2.49 kg in one-rep max strength. They aid in body composition improvement by reducing fat mass and increasing muscle fiber cross-sectional area. Athletes also report decreased muscle soreness, enhanced recovery, and improved performance metrics, especially in aerobic activities. Effect sizes for these benefits range from moderate to large, indicating relevant clinical improvements may be observed within weeks to months of consistent use. The supplementation is particularly beneficial for individuals engaged in intense physical training.

How it works

Amino acids stimulate muscle protein synthesis primarily through the activation of the mTOR pathway, essential for muscle repair and growth. They also enhance energy metabolism and increase nitric oxide production, improving blood flow during physical activity. These biological interactions positively affect both muscular and cardiovascular systems, thus enhancing overall athletic performance and efficiency.

Side effects

Amino acid supplements are generally considered safe when taken as directed; however, some users may experience gastrointestinal disturbances such as bloating and discomfort, with occurrences in over 5% of users. Rare side effects can include allergic reactions and metabolic imbalances particularly resulting from excessive intake. Serious adverse effects are uncommon but may be heightened in individuals with pre-existing kidney issues. Caution is advised when using these supplements alongside blood thinners or diabetes medications. It is recommended that individuals with kidney or liver diseases, as well as pregnant or breastfeeding women, use these supplements only under medical supervision to mitigate potential risks.

Dosage

The standard dosage range for amino acid supplements typically falls between 5-10 grams of BCAAs or 10-20 grams of EAAs per serving, with optimal intake often recommended at 10-30 grams. While no defined maximum dose exists, consumption exceeding 50 grams daily is discouraged due to potential health risks. Timing of intake is crucial; amino acids should ideally be consumed before, during, or after exercise for maximum benefit. Amino acid supplements are available in various forms including liquid, capsule, or powder, and absorption can be enhanced by consuming them alongside carbohydrates. Maintaining proper hydration is also important for optimal absorption.

FAQs

Are amino acid supplements safe?

Yes, they are generally safe when used as directed, but individual tolerance and potential drug interactions should be taken into account.

When should I take amino acids?

It's best to take them around your exercise session, but consistent intake within a balanced diet is equally important.

How quickly can I expect results from amino acid supplementation?

Results, including improved muscle recovery and strength, are typically seen within several weeks to months of consistent use.

Can amino acid supplements enhance performance without training?

No, they should be combined with adequate training and nutrition for significant performance enhancement.

Research Sources

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000391/ – This systematic review examines the effects of BCAA supplementation on exercise recovery and performance, concluding that BCAA intake leads to reduced muscle soreness and improved recovery post-exercise.
  • https://pubmed.ncbi.nlm.nih.gov/22227574/ – This meta-analysis explores the role of essential amino acids in promoting muscle protein synthesis, indicating a strong correlation between EAA supplementation and increased muscle mass during resistance training.
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495848/ – This study investigates the effects of BCAAs on endurance and performance, finding significant improvements in recovery and performance metrics among athletes consuming these amino acids.