King of Bitters
Also known as: Chiretta, King Of Bitters, Kalmegh, Creat, Chuanxinlian, Yijianxi, Lanhelian, Indian Echinacea, Andrographis Paniculata
Overview
Andrographis paniculata, commonly known as ‘king of bitters,’ is an herb traditionally used in Ayurveda and Traditional Chinese Medicine. Andrographis paniculata is used to treat the common cold. It is fairly effective when taken for three to five days after the symptoms first appear. However, there is limited human evidence for the effects of this herb, since research tends to focus on the combination therapy of Andrographis paniculata and Eleutherococcus senticosus, also known as Siberian ginseng, and not on Andrographis paniculata by itself. Andrographis paniculata has also been studied for its anti-cancer effects. In vitro testing and animal research suggest that Andrographis paniculata has an anti-proliferative effect, meaning it is able to slow the spread of cancer cells. The herb does not appear to be able to induce cancer cell death, however. The bioactive ingredients of Andrographis paniculata can be traced back to a single diterpene molecule called andrographolide. Some studies have found that prolonged high-dosage Andrographis paniculata can cause toxicity in the testicles and liver. Further research is needed to confirm these effects, since some follow-up studies, using the same methods, failed to replicate the results. Andrographis paniculata is a promising supplement, though currently it is used most often to alleviate the symptoms of the common cold.
Benefits
Andrographis paniculata works primarily through its active compound, andrographolide, which has been shown to modulate immune responses. It enhances the body's immune response, helping to fight off infections, particularly respiratory infections. The herb may also exert anti-inflammatory effects, which can alleviate symptoms associated with colds and other respiratory conditions. Additionally, its anti-proliferative properties suggest a potential role in inhibiting the growth of certain cancer cells, although more research is needed to fully understand these mechanisms.
How it works
The benefits of Andrographis paniculata include: 1. **Immune Support**: It enhances immune function, helping the body to fight off infections, particularly the common cold and upper respiratory tract infections. 2. **Anti-Inflammatory Effects**: It may reduce inflammation, which can alleviate symptoms of respiratory conditions. 3. **Potential Anti-Cancer Properties**: Some studies suggest it may slow the spread of cancer cells, although it does not induce cancer cell death. 4. **Symptom Relief for Colds**: It is effective in reducing the duration and severity of cold symptoms when taken early.
Side effects
The standard dose of Andrographis paniculata basic root extract is 2,000 – 6,000 mg. Andrographis paniculata root extract tends to have 1-2% andrographolide content, by weight, though up to 4% has been reported. Concentrated root extracts can have an andrographolide content of up to 30%. The standard dose for a concentrated extract is 200mg.
Dosage
Some potential side effects of Andrographis paniculata include gastrointestinal issues such as nausea, diarrhea, and abdominal pain. High doses may lead to toxicity in the liver and testicles. It is important to use caution in individuals with liver disease or those taking medications that affect liver function. Pregnant or breastfeeding women should avoid using Andrographis paniculata due to insufficient safety data.
FAQs
What is King of Bitters used for?
King of Bitters is primarily used for boosting immunity and treating the common cold.
Are there any side effects associated with King of Bitters?
Yes, potential side effects include gastrointestinal issues and possible toxicity at high doses.
How should I take King of Bitters?
The standard dosage is between 2,000 to 6,000 mg of the basic root extract.
Can King of Bitters help with cancer?
Some studies suggest it may have anti-cancer properties, but more research is needed.
Is King of Bitters safe for everyone?
It may not be safe for pregnant or breastfeeding women, or for individuals with liver disease.