ANGELICA POLYMORPHA SINENSIS ROOT EXTRACT
Also known as: Angelica sinensis, Angelica polymorpha sinensis, Dong Quai, Chinese Angelica
Overview
Angelica sinensis, commonly known as Dong Quai or Chinese Angelica, is a plant native to China, with its root widely used in traditional Chinese medicine. The root contains bioactive compounds like ferulic acid and polysaccharides, contributing to its purported health benefits. It is traditionally used to improve circulation and alleviate menstrual cramps. Research on Angelica sinensis is ongoing, exploring its pharmacological effects. While some studies show promise, further rigorous trials are needed to confirm its efficacy and safety. It is available in various forms, including dried root, capsules, and teas. The quality of available evidence is variable, necessitating cautious interpretation of its benefits.
Benefits
Some studies suggest that Angelica sinensis may improve cardiovascular health and reduce menopausal symptoms, although the evidence is not consistently strong. It also exhibits potential anti-inflammatory and antioxidant effects. Women experiencing menstrual discomfort may find it beneficial, but more research is required. Effect sizes are generally small to moderate, and clinical significance varies across studies. Most studies focus on short-term effects, and the time course of benefits is not well-documented. Overall, the evidence supporting the benefits of Angelica sinensis is moderate, and further research is needed to confirm these findings.
How it works
Angelica sinensis is believed to work by modulating blood flow and potentially interacting with estrogen receptors. It may affect both the cardiovascular and reproductive systems. Ferulic acid, a component of Angelica sinensis, has antioxidant properties. The absorption and bioavailability of its active compounds have not been extensively studied, but preparation methods may influence bioavailability. Its primary biological pathways involve interactions with various body systems, contributing to its purported health benefits.
Side effects
Angelica sinensis is generally considered safe when used appropriately, but interactions with certain medications are possible. Common side effects (occurring in more than 5% of users) include gastrointestinal upset and allergic reactions. Uncommon side effects (1-5%) may include skin rashes and headaches. Rare side effects (less than 1%) include severe allergic reactions. It may interact with anticoagulants and diabetes medications. It is contraindicated in pregnancy and breastfeeding due to potential hormonal effects. Caution is advised in individuals with bleeding disorders or those taking anticoagulant medications. Consult a healthcare provider before use, especially if taking medications or having health conditions.
Dosage
The minimum effective dose of Angelica sinensis is not well-established and varies by preparation. Typical dosage ranges are between 1-3 grams of dried root per day. The maximum safe dose is not clearly defined, but high doses may increase the risk of side effects. It is often taken with meals to reduce gastrointestinal upset. Common forms include capsules and teas. Bioavailability may be influenced by the preparation method. There are no specifically identified required cofactors. Consult a healthcare provider to determine the appropriate dosage for individual needs.
FAQs
How should I ensure the quality of Angelica sinensis?
Ensure proper identification and preparation of the herb to avoid adulteration or contamination. Purchase from reputable sources and follow preparation guidelines carefully.
When should I take Angelica sinensis?
Typically taken daily, but timing can vary based on specific health goals. It is often taken with meals to reduce gastrointestinal upset. Consult with a healthcare provider for personalized advice.
What are the expected results from taking Angelica sinensis?
Results are variable, as benefits are not universally confirmed. Some individuals may experience improvements in menstrual symptoms or cardiovascular health, but more research is needed.
Is Angelica sinensis safe to take with other medications?
It may interact with anticoagulants and diabetes medications. Consult a healthcare provider before use, especially if taking medications or having health conditions, to avoid potential interactions.
Can Angelica sinensis cure various health issues?
It is often mistakenly believed to be a cure-all for various health issues without strong evidence. It should not be considered a substitute for conventional medical treatment.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/32425767/ – This study investigates the impact of Angelica sinensis on vascular function. The research suggests potential benefits for improving blood vessel health, which could contribute to cardiovascular wellness. The study highlights the need for further research to confirm these findings and understand the underlying mechanisms.
- https://pubmed.ncbi.nlm.nih.gov/24365638/ – This research explores the effects of Angelica sinensis on menopausal symptoms. The findings indicate that it may help alleviate some discomfort associated with menopause. However, the study emphasizes the importance of larger, more rigorous trials to validate these results.
- https://www.webmd.com/vitamins/ai/ingredientmono-936/dong-quai – This WebMD article provides a general overview of Dong Quai (Angelica sinensis), including its uses, potential benefits, and side effects. It serves as a consumer-friendly resource for understanding the basics of this herbal supplement. The article highlights the need for caution and consultation with healthcare professionals before use.
- https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-angelica-sinensis-oliv-diels-radix-first-version_en.pdf – This report from the European Medicines Agency provides a comprehensive assessment of Angelica sinensis. It includes detailed information on its traditional uses, safety, and efficacy based on available scientific evidence. The report serves as a regulatory document for healthcare professionals and researchers.
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1510976/full – This article highlights the potential pharmacological effects of Angelica sinensis polysaccharides, including antioxidant and anti-inflammatory actions. It suggests that these polysaccharides may contribute to the overall health benefits associated with the herb. The research supports further investigation into the specific mechanisms of action of these compounds.