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Anise seed

Also known as: Anise, Aniseed, Pimpinella anisum

Overview

Aniseed, derived from the seeds of the *Pimpinella anisum* plant, is an herbal supplement traditionally used for its aromatic and medicinal properties. Its key components include *trans*-anethole, estragole, and other bioactive compounds. It has been historically used as a carminative and for various gastrointestinal issues. Research on aniseed is still emerging, with limited large-scale clinical trials, and the quality of available evidence varies, with some studies showing promise but often limited by small sample sizes and regional focus. Aniseed is available in various forms, including seed powder and essential oil capsules. It is believed to exert its effects through anti-inflammatory, antioxidant, and antimicrobial actions.

Benefits

Aniseed has shown potential in reducing abdominal pain, anorexia, and diarrhea in COVID-19 patients, with significant risk ratios for symptom improvement. Aniseed oil may also reduce symptoms of Irritable Bowel Syndrome (IBS), including diarrhea, bloating, and abdominal pain. Some evidence suggests that aniseed may alleviate premenstrual syndrome symptoms and have hypoglycemic effects. These benefits are typically observed within weeks of use. However, effect sizes are generally small to moderate, and more robust studies are needed to confirm these findings. Potential benefits are seen for women with menstrual disorders and individuals with gastrointestinal issues.

How it works

Aniseed's bioactive compounds, particularly *trans*-anethole, exhibit anti-inflammatory, antioxidant, and antimicrobial properties. It influences gastrointestinal motility and may modulate immune responses. While the exact molecular targets are not well-defined, aniseed likely interacts with various receptors and enzymes related to inflammation and digestion. The essential oils in aniseed are generally well-absorbed, contributing to its systemic effects. These actions collectively contribute to the observed benefits in gastrointestinal and other conditions.

Side effects

Aniseed is generally considered safe when used appropriately. Common side effects include mild gastrointestinal upset. Uncommon side effects may include allergic reactions. Rare side effects are not well-documented. Aniseed may interact with blood thinners and diabetes medications, so caution is advised. It is contraindicated during pregnancy and breastfeeding due to a lack of safety data. Individuals with allergies to plants in the Apiaceae family should also exercise caution. It is important to start with low doses to assess tolerance and monitor for any adverse reactions.

Dosage

While the minimum effective dose of aniseed is not well-established, typical dosages range from 5-25 grams of seed powder or 600 mg of seed oil per day. It is best taken with meals to reduce gastrointestinal upset. Seed powder or oil capsules are common forms. Bioavailability may be enhanced with fatty meals. There are no documented required cofactors. Due to limited research, the maximum safe dose is not clearly defined, so it is advisable to stay within the recommended dosage ranges and consult with a healthcare professional.

FAQs

How should I take aniseed?

Start with low doses to assess tolerance. Take with meals to minimize gastrointestinal side effects. Seed powder or oil capsules are common forms.

Is aniseed safe during pregnancy or breastfeeding?

No, aniseed is contraindicated during pregnancy and breastfeeding due to a lack of safety data. Avoid use during these periods.

How long does it take to see results from aniseed?

You may see improvements in gastrointestinal symptoms within weeks of consistent use. However, individual results may vary.

Can aniseed cure digestive issues?

Aniseed is not a cure-all for digestive issues; individual results may vary. It may help alleviate symptoms, but it's important to consult with a healthcare professional for comprehensive care.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC10824915/ – A randomized controlled trial (n=225) found that aniseed powder improved abdominal pain, anorexia, and diarrhea in COVID-19 patients over a 2-week period. The study suggests aniseed may be a beneficial adjunct therapy for managing gastrointestinal symptoms associated with COVID-19, although the small aniseed group size and regional focus limit the generalizability of the findings.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC3405664/ – This review highlights the antimicrobial, antifungal, antiviral, antioxidant, and muscle relaxant activities of aniseed. While the review suggests a wide range of potential pharmacological properties, it also notes that most studies are small-scale or in vitro, indicating a need for more robust clinical trials to confirm these effects.
  • https://journals.lww.com/nutritiontodayonline/fulltext/2022/03000/anise__potential_health_benefits.10.aspx – This article discusses the potential health benefits of anise, including its use in traditional medicine for various ailments. It highlights the presence of bioactive compounds like anethole and their potential roles in providing health benefits, but also emphasizes the need for more research to fully understand and validate these effects.
  • https://www.mdpi.com/1660-4601/17/10 – This source likely contains research or a review related to aniseed, potentially covering its chemical composition, pharmacological activities, or health benefits. Further examination of the full text would be needed to provide a more detailed summary of its key findings and implications.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC9699062/ – A randomized controlled trial (n=75) found that aniseed oil reduced IBS symptoms like diarrhea and bloating over a 4-week period. The study suggests that aniseed oil may be a promising treatment option for managing IBS symptoms, although the small sample size warrants further investigation with larger, more diverse populations.

Supplements Containing Anise seed

Herb-Lax by Shaklee
39

Herb-Lax

Shaklee

Score: 39/100
DGL by Natural Factors
73

DGL

Natural Factors

Score: 73/100
DGL by Natural Factors
73

DGL

Natural Factors

Score: 73/100
Sweetish Bitters by Gaia Herbs
73

Sweetish Bitters

Gaia Herbs

Score: 73/100
Candida Support by Dr. Tobias
63

Candida Support

Dr. Tobias

Score: 63/100
Anise Alcohol Free by Hawaii Pharm
60

Anise Alcohol Free

Hawaii Pharm

Score: 60/100
Anise by Hawaii Pharm
63

Anise

Hawaii Pharm

Score: 63/100