Astragalus Complanatus Seed Extract
Also known as: Astragalus complanatus, milkvetch, locoweed, Astragalus complanatus Seed Extract
Overview
Astragalus complanatus Seed Extract is derived from the seeds of the Astragalus complanatus plant, widely utilized in traditional medicine for its various health benefits. It belongs to the Astragalus genus, known for its adaptogenic and immune-supporting properties. Commonly used forms include capsules and teas. The extract contains bioactive compounds such as polysaccharides, flavonoids, and saponins, which are believed to contribute to its health-promoting effects. Although Astragalus species, particularly Astragalus membranaceus, have been more extensively researched, the specific benefits and evidence for Astragalus complanatus Seed Extract remain limited, necessitating further studies to fully understand its efficacy and safety.
Benefits
Research on the specific benefits of Astragalus complanatus Seed Extract is limited; however, related species such as Astragalus membranaceus have demonstrated immunomodulatory effects, including reduction of proinflammatory cytokines and enhancement of cellular immunity. Studies indicate that Astragalus species may also support cardiovascular health, particularly in heart failure patients by improving left ventricular function. These effects have been reported in clinical studies with significant evidence, particularly in populations with compromised immune systems and cardiovascular issues. Benefits from Astragalus membranaceus have been observed within weeks to months of consistent use.
How it works
The bioactive components of Astragalus, including Astragaloside IV, modulate immune responses primarily by altering cytokine levels and enhancing cellular immunity. Additionally, Astragalus extracts exhibit anti-inflammatory and antioxidant properties, affecting various biological pathways related to immunity and cardiovascular health. This interaction with the immune and cardiovascular systems helps to address conditions that benefit from immune support and improved heart function.
Side effects
Astragalus complanatus Seed Extract is generally considered safe for use, although specific data on its side effects is sparse. Common side effects may include gastrointestinal upset or rare allergic reactions, typical for herbal extracts. Potential interactions with immunosuppressants and blood thinners should be noted, as Astragalus has immunomodulatory properties. Data on contraindications exists concerning pregnancy and breastfeeding due to insufficient safety data. Additionally, caution is advised for individuals with autoimmune diseases or those on medications that could interact negatively with Astragalus extracts.
Dosage
While a specific minimum effective dose for Astragalus complanatus Seed Extract has not been established, general guidance for Astragalus extracts typically ranges from 500 mg to 2 grams per day. There is no upper established limit, but high doses should be used cautiously. The timing of administration, ideally with meals, can mitigate gastrointestinal discomfort. Forms such as capsules or teas are common, and bioavailability may potentially improve with fatty meals.
FAQs
Is Astragalus complanatus safe to use?
Generally considered safe, but specific safety data is limited. Consult a healthcare provider before use, especially if you are on medications.
How should I take Astragalus complanatus?
It can be taken daily, preferably with meals to optimize absorption and minimize gastrointestinal upset.
What benefits can I expect from Astragalus?
Potential benefits include immune support and cardiovascular improvements, though results may vary by individual.
Can I use Astragalus if I’m pregnant or breastfeeding?
Avoid use during pregnancy and breastfeeding due to insufficient safety research.
Is there a risk of side effects?
Side effects are generally rare but can include gastrointestinal issues. Monitor for any unusual symptoms.
Research Sources
- https://karger.com/cmr/article-abstract/30/6/535/869772/The-Effect-of-Astragalus-on-Humoral-and-Cellular?redirectedFrom=fulltext – This systematic review involving 1,094 participants showed that Astragalus membranaceus significantly reduces proinflammatory cytokines and enhances cellular immunity, pointing to its potential as an immunomodulatory agent.
- https://pubmed.ncbi.nlm.nih.gov/38464590/ – A comprehensive meta-analysis on Astragalus membranaceus for heart failure involving 1,565 patients indicated improvements in left ventricular remodeling and overall cardiac function, supporting its cardiovascular benefits.
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1345797/full – Review discusses potential anticancer and immunomodulatory effects of Astragalus species, emphasizing the need for further research on specific Astragalus varieties including Astragalus complanatus.
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11479930/ – This review outlines the beneficial properties of various Astragalus species, hinting at their applications in treating diverse medical conditions, although specific data on Astragalus complanatus is lacking.
- https://www.mdpi.com/2072-6643/13/8/2564 – Research highlights the nutritional and therapeutic potential of several Astragalus species, stressing the relevance of polysaccharides and saponins but calls for more focused studies on less researched species.