Astrazyme
Also known as: Astrazyme, ERCC1, AstraGin
Overview
Astrazyme is a proprietary blend designed to enhance protein digestion and nutrient absorption. It combines proteolytic enzymes (ERCC1) with extracts of Astragalus membranaceus and Panax notoginseng (AstraGin). Primarily used to improve protein digestion and absorption, it is marketed to benefit individuals with digestive issues or those seeking enhanced nutrient uptake. ERCC1 functions as a proteolytic enzyme, while AstraGin is intended to enhance bioavailability. Available evidence is primarily based on in vitro studies and lacks robust clinical trials. The quality of available evidence is limited, with most studies being manufacturer-sponsored. More independent research is needed to validate its efficacy and safety in humans. It is available in capsule or tablet form and is typically taken with meals.
Benefits
In vitro studies suggest that Astrazyme can enhance protein digestion and nutrient absorption. ERCC1 has been shown to efficiently hydrolyze bovine hemoglobin, and AstraGin has demonstrated increased peptide and amino acid absorption in Caco-2 cells. Potential benefits may extend to individuals with impaired digestion or absorption, although clinical evidence is lacking. While these findings are promising, the absence of human trials limits the clinical significance of these results. Further research is needed to confirm these benefits in human populations and to determine the extent of their clinical relevance.
How it works
Astrazyme enhances protein digestion through the action of proteolytic enzymes like ERCC1, which break down proteins into smaller peptides and amino acids. AstraGin, a component of Astrazyme, is believed to improve nutrient absorption in the gastrointestinal system. In vitro studies suggest that AstraGin increases the absorption of peptides and amino acids. The primary biological pathway involves enhancing protein digestion and improving nutrient uptake via bioavailability enhancers. However, the precise molecular targets and mechanisms in human studies are not well-defined.
Side effects
Due to the limited availability of clinical trials, the overall safety assessment of Astrazyme is based primarily on the known safety profiles of its individual components. Common, uncommon, and rare side effects are not well-documented. Potential interactions with anticoagulants or other medications affecting digestion are possible but not well-studied. Caution is advised in individuals with severe digestive disorders, and consultation with a healthcare provider is recommended before use. Pregnant or breastfeeding women should also consult healthcare providers before using Astrazyme. More comprehensive research is needed to fully characterize its safety profile.
Dosage
The minimum effective dose of Astrazyme has not been established in clinical trials. Manufacturer recommendations vary, but typically involve taking the supplement with meals to enhance digestion. The optimal dosage ranges and maximum safe dose are not established. AstraGin is intended to enhance absorption. Capsules or tablets are common forms. Due to the lack of clinical data, it is important to adhere to manufacturer guidelines and consult with a healthcare provider before use. Required cofactors are not documented.
FAQs
What is Astrazyme and what is it used for?
Astrazyme is a blend of enzymes and plant extracts intended to aid digestion and nutrient absorption. It is primarily used to improve protein digestion, but clinical evidence is limited.
Is Astrazyme safe?
Astrazyme is generally considered safe based on its components, but more research is needed. Consult a healthcare provider before use, especially if you have digestive issues or are pregnant/breastfeeding.
How should I take Astrazyme?
Take Astrazyme with meals to enhance digestion. Follow the manufacturer's recommended dosage. Clinical evidence supporting specific timing and administration is limited.
What results can I expect from taking Astrazyme?
Astrazyme may improve protein digestion and nutrient absorption, though clinical evidence is limited. It should not be seen as a cure-all for digestive issues without sufficient clinical backing.
Research Sources
- https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.844242/full – This article discusses the potential benefits of various nutrients and supplements on gut health. While it doesn't specifically focus on Astrazyme, it provides context on how nutrients can impact gut microbiota and overall digestive health, which is relevant to understanding the intended effects of Astrazyme.
- https://www.stauberusa.com/wp-content/uploads/2024/10/AstrazymeBooklet.pdf – This is a manufacturer's booklet on Astrazyme, detailing its composition and potential benefits. It highlights in vitro studies showing that ERCC1 efficiently hydrolyzes bovine hemoglobin and AstraGin enhances peptide and amino acid absorption in Caco-2 cells. However, it's important to note that the information is from a manufacturer-sponsored source.
- https://pubmed.ncbi.nlm.nih.gov/37701221/ – This PubMed entry links to research on nutrient absorption and bioavailability. While it may not directly address Astrazyme, it provides relevant background information on factors influencing nutrient uptake, which is pertinent to understanding the intended function of Astrazyme's components.
- https://reviewmeta.com/brand/astrazyme – ReviewMeta analyzes customer reviews to identify potentially biased or unreliable reviews. This source can provide insights into consumer perceptions and experiences with Astrazyme, but it does not offer scientific evidence regarding its efficacy or safety.
- https://www.astrazyme.com – This is the official website for Astrazyme, providing information on the product's features and benefits. It is a primary source for understanding the manufacturer's claims, but it should be interpreted with caution due to potential bias.
Supplements Containing Astrazyme

Digestech
Onnit

Enzorb Digestive Enzymes
Sunwarrior

kApex
BiOptimizers

Masszymes
BiOptimizers

VegZymes
BiOptimizers

P3E
Organixx

Enzorb Digestive Enzymes
Sunwarrior

TOTAL GUT HEALTH
ONNIT®

SYSTEMIC ENZYMES
HEALTHY REFLECTIONS®

TOTAL GUT HEALTH™
ONNIT®

SULFORAXYM
SULFORAXYM

NATTOXYM® NATTOKINASE BLEND
U.S. ENZYMES