Bifidobacterium Animalis Lactis Bl818
Also known as: Bifidobacterium lactis, B. animalis subsp. lactis, Bifidobacterium animalis lactis, Bifidobacterium animalis subsp. lactis
Overview
*Bifidobacterium animalis* subsp. *lactis* is a probiotic bacterium naturally found in the human and animal gastrointestinal tract. It's widely used as a dietary supplement and food additive, particularly in yogurt and fermented milk, to promote gastrointestinal health and boost immune function. This strain is known for its ability to adhere to the intestinal mucosa, produce antimicrobial substances, and modulate the immune system. Research on *B. animalis subsp. lactis* is extensive, including numerous randomized controlled trials (RCTs) and systematic reviews, providing high-quality evidence of its effects. It is primarily used to alleviate gastrointestinal symptoms, enhance gut microbiome composition, and potentially promote growth in children. The bacterium interacts with the gut and immune system, enhancing gut barrier function and immune response. It is generally well-tolerated, making it a popular choice for probiotic supplementation.
Benefits
*Bifidobacterium animalis* subsp. *lactis* offers several evidence-based benefits, primarily related to gastrointestinal health. A meta-analysis showed it increases defecation frequency (SMD, 0.26) and reduces colonic transit time (SMD, -0.34) in short-term treatment, improving stool consistency in healthy individuals (SMD, 0.76). It also improves bowel movement frequency and stool quality in adults with functional constipation. Studies indicate that *B. animalis subsp. lactis* can positively impact gut microbiome composition, increasing the abundance of beneficial bacteria. Some research suggests it may promote height growth in children, particularly those with shorter stature, although this requires further validation. These benefits are most pronounced in healthy adults experiencing gastrointestinal discomfort and children needing gut microbiome support.
How it works
*Bifidobacterium animalis* subsp. *lactis* exerts its beneficial effects through several mechanisms. It adheres to the intestinal mucosa, creating a barrier against pathogens. The bacterium produces antimicrobial substances like acids, peroxides, and bacteriocins, which inhibit the growth of harmful bacteria. It also modulates the immune system by interacting with epithelial cells and gut-associated lymphoid tissue (GALT), enhancing gut barrier function and immune response. By crowding out pathogens and maintaining a healthy gut microbiota, *B. animalis subsp. lactis* contributes to overall gastrointestinal health and immune function.
Side effects
*Bifidobacterium animalis* subsp. *lactis* is generally considered safe, with mild and transient side effects. Common side effects include bloating, gas, and abdominal discomfort, typically occurring in more than 5% of users. Uncommon side effects (1-5%) may include allergic reactions or exacerbation of underlying gastrointestinal conditions. Rare side effects (<1%) such as anaphylaxis or sepsis are possible in immunocompromised individuals but are extremely rare. There are no significant known drug interactions, but caution is advised for patients with compromised immune systems or severe underlying health conditions. It is generally contraindicated in patients with severe immunodeficiency or those who are critically ill. Pregnant or breastfeeding women and children should consult healthcare providers before use, although it is generally well-tolerated in healthy children.
Dosage
The typical effective dose of *Bifidobacterium animalis* subsp. *lactis* ranges from 1 to 10 billion Colony Forming Units (CFU) per day. For general gastrointestinal health, a dosage of 3-8 billion CFU per day is commonly recommended. While there is no established maximum safe dose, dosages above 10 billion CFU per day are less frequently studied. It is best taken with meals to enhance survival and colonization in the gut. *B. animalis subsp. lactis* is available in various forms, including capsules, powders, and fermented foods like yogurt. The food matrix and storage conditions can affect its viability and absorption. A healthy diet and adequate hydration can support its efficacy.
FAQs
Is *Bifidobacterium animalis* subsp. *lactis* safe?
It is generally safe for most people. However, individuals with compromised immune systems or severe health conditions should consult a healthcare provider before use.
When is the best time to take it?
It is best taken with meals to enhance survival and colonization in the gut, maximizing its beneficial effects on digestion and gut health.
What results can I expect?
You may experience improvements in gastrointestinal symptoms such as increased defecation frequency and improved stool consistency. Individual results can vary.
Is it a cure-all for gastrointestinal issues?
No, it is not a cure-all. It can help manage symptoms and improve gut health, but individual results may vary, and it should be part of a comprehensive approach.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/34918142/ – This systematic review and meta-analysis of 13 studies found that *B. animalis subsp. lactis* supplementation increased defecation frequency, reduced colonic transit time, and improved stool consistency in healthy adults. The study highlights the potential of this probiotic for improving gastrointestinal function but calls for more high-quality RCTs to develop clinical protocols.
- https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2023.1165771/full – A randomized controlled trial involving 59 children aged 1-5 years showed that *B. animalis subsp. lactis* BB-12 significantly increased the abundance of this strain in the gut and altered the gut microbiome composition. The study suggests potential benefits for gut health in children, though the small sample size and short duration limit the generalizability of the findings.
- https://www.medrxiv.org/content/10.1101/2024.10.21.24315871v1.full – This randomized controlled trial with 124 children aged 3-7 years indicated that *B. animalis subsp. lactis* BL-11 may promote height growth, particularly in children with shorter heights. However, the study's lack of a placebo control and the need for further validation suggest that these results should be interpreted with caution.
- https://journals.lww.com/md-journal/fulltext/2022/10280/the_effect_of_probiotics_on_functional.3.aspx – This study examined the effect of probiotics, including *B. animalis subsp. lactis*, on functional constipation in adults. The probiotic cocktail improved the weekly frequency of bowel movements and stool quality, suggesting a potential benefit for managing constipation symptoms.
- https://internationalprobiotics.org/home/bifidobacterium-lactis/ – This resource provides general information about *Bifidobacterium lactis*, highlighting its role in supporting digestive health and immune function. It discusses the probiotic's ability to colonize the gut and produce beneficial compounds that contribute to overall well-being.
Recommended Articles
Top Ingredients for Optimal Gut Health
Fiber, probiotics, prebiotics, hydration, and fermented foods are crucial for maintaining healthy digestion and gut function.
Best Probiotic Strains & CFU for Health
Certain probiotic strains like Lactobacillus and Bifidobacterium, with CFU counts ranging from 1 billion for general wellness to 100 billion for conditions like IBS, are most beneficial.
Best Probiotic Strains for Your Health Goals
Certain probiotic strains offer targeted benefits for digestive health, immune support, weight management, and mental health.
Probiotics for IBS: Efficacy and Safety Insights
Probiotics significantly improve IBS symptoms and quality of life, with efficacy depending on the strain.