Bifidobacterium Longum Longum 35624
Also known as: Bifidobacterium longum 35624, B. longum 35624
Overview
Bifidobacterium longum 35624 is a probiotic strain of bacteria commonly found in the human gastrointestinal tract. It is primarily recognized for its beneficial role in gut health, particularly for individuals suffering from irritable bowel syndrome (IBS). This strain helps to maintain a healthy gut microbiota and has been shown to have immune-modulating effects. Research indicates that B. longum 35624 significantly reduces symptoms of IBS, such as abdominal pain and bloating, while improving the overall quality of life for sufferers. The strain is typically consumed in capsule or powder form and is available as a dietary supplement.
Benefits
Bifidobacterium longum 35624 has demonstrated benefits for individuals with Irritable Bowel Syndrome (IBS). Randomized controlled trials (RCTs) show a significant reduction in Total IBS Symptom Score by an average of 43.4% over 8 weeks, leading to pronounced benefits for those diagnosed with IBS. Patients also report an enhanced quality of life based on IBS-QoL questionnaire results, primarily validated in IBS populations. Furthermore, studies suggest a potential increase in T-regulatory cells and decreased inflammation biomarkers, acknowledged in both healthy and IBS-affected individuals. Long-term supplementation shows stronger effects in symptom relief and quality of life improvement.
How it works
Bifidobacterium longum 35624 operates by modulating the gut microbiota composition, enhancing the gut barrier's functionality, and influencing both local and systemic immune responses. This strain interacts predominantly with the gastrointestinal system where it alters cytokine production and immune cell activity, contributing to lowered inflammation and improved gut health. Importantly, its action is limited to the gut, as it resides in the gastrointestinal tract and does not enter systemic circulation.
Side effects
Bifidobacterium longum 35624 is generally well-tolerated; mild gastrointestinal symptoms like bloating or gas may occur in over 5% of users at the onset. Severe side effects are uncommon but may include allergic reactions. Those with severe immunocompromised states should avoid this supplement, while pregnant or breastfeeding women should consult healthcare providers due to limited data. No significant drug interactions have been reported. Overall, the safety profile is positive, substantiated by clinical studies.
Dosage
A typical dosage of Bifidobacterium longum 35624 is around 1 billion CFU (colony-forming units) daily, with ranges from 1 to 10 billion CFU being common. Larger doses did not necessarily correlate to improved outcomes; 10 billion CFU shows overall safety. Taking the supplement with food is recommended to optimize the survival of the strains passing through stomach acid. Capsules are preferred for buffering against acidity. Up to 10 billion CFU is deemed safe based on existing studies.
FAQs
How should I store *B. longum* 35624 supplements?
Store in a cool, dry place to maintain bacterial viability.
Is it safe for everyone to use?
Generally safe; however, consult a healthcare professional if you are immunocompromised.
When is the best time to take the supplement?
It is best taken once daily with food for optimal efficacy.
When can I expect results?
Improvement in IBS symptoms is typically observed within weeks of consistent supplementation.
Is this a cure for IBS?
No, it helps manage symptoms but is not a cure.
Supplements Containing Bifidobacterium Longum Longum 35624
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