Biocore Optimum Complete
Also known as: Alpha-galactosidase, α-Galactosidase, Biocore Optimum Complete (Ingredient), Melibiase
Overview
Alpha-galactosidase is a digestive enzyme that breaks down complex carbohydrates, specifically galactosides like raffinose, found in foods such as beans and cruciferous vegetables. It is naturally found in plants and microorganisms. As a dietary supplement, alpha-galactosidase is used to alleviate gas, bloating, and abdominal discomfort associated with consuming these foods. The enzyme works by hydrolyzing galactosides into simpler sugars, preventing their fermentation in the colon, which produces gas. It is available in capsule or tablet form and is typically taken with meals containing galactose-rich foods. While generally considered safe, individuals with allergies should exercise caution. Research on alpha-galactosidase supports its efficacy in reducing gas and bloating, but high-quality systematic reviews specifically on Biocore Optimum Complete are limited.
Benefits
Alpha-galactosidase primarily reduces gas and bloating by breaking down complex sugars that are difficult for the body to digest. This is particularly beneficial for individuals who consume diets high in legumes and cruciferous vegetables. By hydrolyzing galactosides into simpler sugars, alpha-galactosidase prevents undigested carbohydrates from reaching the colon, where they can be fermented by bacteria, leading to gas production. Some studies suggest it may support overall digestive health by facilitating the digestion of proteins, fats, and starches, although this is a secondary effect. Benefits are typically observed shortly after consumption, as the enzyme acts on ingested food.
How it works
Alpha-galactosidase functions by hydrolyzing galactosides, a type of complex carbohydrate, into simpler, more easily digestible sugars. This enzymatic action occurs primarily in the small intestine. By breaking down these complex sugars before they reach the colon, alpha-galactosidase prevents their fermentation by gut bacteria. This fermentation process is a major cause of gas production, bloating, and abdominal discomfort. The enzyme targets galactose-containing sugars, reducing the amount of undigested carbohydrates that reach the colon.
Side effects
Alpha-galactosidase is generally considered safe for most individuals when taken as directed. Common side effects are rare, but some people may experience mild gastrointestinal upset, such as nausea or diarrhea, if taken in excessive amounts. Allergic reactions are uncommon but possible, particularly in individuals with known allergies to fungal-derived enzymes. There are no significant drug interactions reported with alpha-galactosidase. Individuals with known allergies to alpha-galactosidase or other components of the supplement should avoid its use. Pregnant or breastfeeding women should consult a healthcare provider before using alpha-galactosidase. While rare, it's important to discontinue use and seek medical attention if any signs of an allergic reaction occur.
Dosage
The optimal dosage of alpha-galactosidase varies depending on the individual and the amount of galactose-rich foods consumed. Typically, it is recommended to take alpha-galactosidase with meals containing legumes or other foods known to cause gas and bloating. The dosage should provide sufficient enzymatic activity to break down the galactosides present in the meal. While there is no established maximum safe dose, excessive intake is unlikely to cause significant harm. It is available in capsule or tablet form, and timing is crucial; it should be taken just before or at the beginning of the meal to be effective. No specific cofactors are required for its activity.
FAQs
Is alpha-galactosidase safe to use?
Alpha-galactosidase is generally safe, but consult a healthcare provider if you have allergies or are pregnant/breastfeeding.
When should I take alpha-galactosidase?
Take alpha-galactosidase with meals containing legumes or other galactose-rich foods for best results.
What results can I expect from taking alpha-galactosidase?
You can expect reduced gas and bloating symptoms after consuming foods that typically cause these issues.
Is alpha-galactosidase a cure for all digestive issues?
No, it specifically targets galactose-containing sugars and is not a cure for all digestive problems.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9524349/ – This article discusses various enzyme supplements and their role in managing digestive disorders. It highlights the potential benefits of enzymes like alpha-galactosidase in improving digestion and reducing gastrointestinal symptoms. The review emphasizes the importance of enzyme supplementation in individuals with enzyme deficiencies or digestive issues.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7527782/ – This study explores the use of digestive enzymes to treat exocrine pancreatic insufficiency. While it does not focus specifically on alpha-galactosidase, it provides context on the broader use of enzyme supplements in managing digestive health. The research underscores the potential of enzyme therapies to improve nutrient absorption and alleviate digestive symptoms.
- https://www.ulprospector.com/en/na/Food/Detail/6662/223738/BioCore-Optimum-Complete-I – This is a product information page for BioCore Optimum Complete, detailing its composition and intended use as a digestive aid. It highlights the enzyme blend's ability to support the digestion of various food components. The page provides information on the product's features and benefits as marketed by the manufacturer.
- https://pubmed-ncbi-nlm-nih-gov.auth.lib.niu.edu/38127505/ – This study investigates the impact of enzyme supplementation on digestive health. The research suggests that enzymes like alpha-galactosidase can improve the digestion of specific carbohydrates, reducing symptoms like gas and bloating. The findings support the use of enzyme supplements as a strategy to enhance digestive comfort and efficiency.
- https://onlinelibrary.wiley.com/doi/10.1111/jan.17007?af=R – This article discusses the role of dietary interventions in managing digestive disorders. It explores the potential of enzyme supplementation, including alpha-galactosidase, to alleviate symptoms associated with carbohydrate malabsorption. The review highlights the importance of tailored dietary strategies in improving digestive health and overall well-being.
Supplements Containing Biocore Optimum Complete

Probiotic Digestive Support
Vitamer Laboratories

Greens Lime
GHOST

Greens Original
GHOST

Greens Guava Berry
GHOST

ZenZymes+
Zenwise

BioCore Optimum Complete
Swanson Ultra

No Bloat
Zenwise

Digestive Support
Bariatric Fusion

Complete-GI Unflavored
PEScience

Greens Superfood Iced Tea Lemonade
GHOST

Symbiont-GI
PEScience
BioCore Optimum Complete
Swanson
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