ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Blue Vervain Extract

Also known as: Verbena hastata, Common vervain, American vervain, Wild hyssop, Blue Vervain

Overview

Blue Vervain (*Verbena hastata*) is a perennial herb native to North America and Europe, recognized in traditional herbal medicine for its calming and sedative properties. This herb is particularly rich in flavonoids, phenolic acids, and iridoid glycosides, which may contribute to its biological effects. Although widely used for symptoms of anxiety and insomnia, research supporting these uses primarily stems from small-scale studies and anecdotal evidence, rather than comprehensive clinical trials, indicating a need for further investigation. The current research maturity level is deemed relatively weak, producing a cautionary stance regarding definitive conclusions about its efficacy and safety, necessitating additional studies to substantiate its traditional applications and explore its full potential as a therapeutic agent.

Benefits

While Blue Vervain is largely associated with potential benefits for anxiety and insomnia, scientific validation remains scant, with much of the evidence being anecdotal. Some traditional practitioners claim antioxidant and anti-inflammatory properties, but robust human studies to confirm these effects are absent. Consequently, there are no specific populations that show consistent benefits from its use, underscoring the necessity for further research. The evidence is insufficient to endorse its efficacy significantly, thereby marking a gap in clinical relevance and documented effect sizes, further indicating the need for high-quality studies.

How it works

The exact mechanism of action for Blue Vervain remains largely unexplored. However, it is suggested that the herb's flavonoids may interact with neurotransmitter systems in the body, which could modulate the nervous system and induce calming effects. Unfortunately, specific biological pathways and molecular targets have not been well-defined in scientific literature. Furthermore, the absorption and bioavailability of its active compounds when consumed in supplement form warrant further study, emphasizing the need for more comprehensive research to elucidate these unknowns.

Side effects

Blue Vervain is generally considered safe when used in traditional amounts, yet comprehensive long-term safety data is limited. Common side effects have not been rigorously documented, although some users report experiencing mild allergic reactions or gastrointestinal discomfort. There is a potential for drug interactions, particularly with sedatives and antidepressants, though existing studies on this matter are sparse. Caution is recommended for pregnant or breastfeeding women, and its usage should be approached with care in children and individuals with liver or kidney disorders. Although serious side effects appear to be rare, individual reactions to the herb can vary, necessitating a cautious approach.

Dosage

Currently, there is no standardized dosage established for Blue Vervain due to the lack of rigorous clinical evidence. Traditionally, it is consumed in forms such as teas or tinctures, often recommended for nightly use to assist with sleep. However, specific dosages can vary considerably among individuals, and no defined maximum safe dose exists. It is advisable for individuals to seek guidance from healthcare professionals for personalized advice on dosage. Available forms include tea, tinctures, and capsules, with no particular form shown to be systematically more effective than others. Users should be mindful of their personal tolerances and existing health conditions when considering supplementation.

FAQs

What is Blue Vervain used for?

Blue Vervain is commonly used as a calming agent for anxiety and insomnia, though scientific evidence supporting its efficacy is limited.

Is Blue Vervain safe?

Generally considered safe in traditional doses, long-term use and drug interactions are not well-studied.

When should I take Blue Vervain?

It is typically recommended to take Blue Vervain before bedtime to assist with sleep.

What results can I expect?

Due to limited evidence, significant benefits cannot be guaranteed; individual results may vary.

Are there any misconceptions about Blue Vervain?

Many assume Blue Vervain is effective for anxiety, but solid clinical evidence is lacking.

Supplements Containing Blue Vervain Extract

Blue Vervain by Hawaii Pharm
53

Blue Vervain

Hawaii Pharm

Score: 53/100
Blue Vervain Non-Alcohol by Hawaii Pharm
73

Blue Vervain Non-Alcohol

Hawaii Pharm

Score: 73/100
Sleep Support Alcohol Free by Hawaii Pharm
58

Sleep Support Alcohol Free

Hawaii Pharm

Score: 58/100
California Poppy Passionflower and Vervain Alcohol Free by Hawaii Pharm
55

California Poppy Passionflower and Vervain Alcohol Free

Hawaii Pharm

Score: 55/100
California Poppy Passionflower and Vervain by Hawaii Pharm
60

California Poppy Passionflower and Vervain

Hawaii Pharm

Score: 60/100
Sleep Support by Hawaii Pharm
63

Sleep Support

Hawaii Pharm

Score: 63/100
BLUE VERVAIN SPAGYRIC TINCTURE by LOST EMPIRE HERBS
55

BLUE VERVAIN SPAGYRIC TINCTURE

LOST EMPIRE HERBS

Score: 55/100