Bone Optima Organic Calcified Algae Powder
Also known as: Bone Optima Organic Calcified Algae Powder, AlgaeCal, calcified red algae powder, calcified marine algae, Lithothamnion spp.
Overview
Lithothamnion spp. is a calcified marine red algae, the primary source of Bone Optima Organic Calcified Algae Powder. This supplement is a plant-derived source of calcium carbonate, naturally integrated with a broad spectrum of trace minerals including magnesium, manganese, selenium, and strontium. Unlike conventional calcium supplements, its unique plant matrix is believed to enhance bioavailability and efficacy. It is primarily utilized to support bone health, particularly in postmenopausal women and older adults, by providing essential nutrients that contribute to increased bone mineral density (BMD). Research indicates its potential to stimulate osteoblast activity and promote bone formation, offering a comprehensive approach to skeletal support.
Benefits
The primary benefit of calcified algae powder is its ability to increase bone mineral density (BMD). A 7-year longitudinal trial involving 172 postmenopausal women (mean age ~65) demonstrated a statistically significant increase in BMD of approximately 1.04% per year, culminating in a 7.3% increase over seven years. This increase is clinically meaningful, as typical bone loss in this demographic is 1-2% annually. Comparative in vitro studies have shown that algae-based calcium significantly enhances osteoblast activity markers (alkaline phosphatase, DNA synthesis, calcium deposition) more effectively than calcium carbonate or citrate, suggesting superior bone formation potential. Additionally, it may reduce oxidative stress in osteoblast cells. These benefits are particularly relevant for postmenopausal women and older adults at risk of osteoporosis, with improvements observed over long-term supplementation (1 to 7 years).
How it works
Calcified algae powder provides a bioavailable source of calcium and a complex of trace minerals essential for bone matrix formation and mineralization. Its unique plant matrix is thought to improve calcium absorption and utilization compared to isolated calcium salts. At a cellular level, it enhances the proliferation and activity of osteoblasts, which are the bone-forming cells. This is evidenced by increased markers such as alkaline phosphatase activity and DNA synthesis in bone cells. The supplement promotes the deposition of calcium into bone tissue and may also reduce oxidative stress within bone cells, contributing to overall bone health and integrity.
Side effects
Calcified algae powder has demonstrated a broad-spectrum safety profile, with no adverse effects reported in long-term human studies. Clinical trials have not indicated any common side effects above a 5% incidence, nor have there been significant reports of uncommon or rare side effects in peer-reviewed literature. While generally safe, standard contraindications for calcium supplementation apply, such as hypercalcemia. Although no well-documented drug interactions exist, caution is advised when co-administering with certain medications like bisphosphonates or tetracyclines, as calcium can interfere with their absorption. Data on safety in pregnant or lactating women are limited, but it appears safe for older adults.
Dosage
Clinical studies suggest an optimal dosage range of approximately 720–1000 mg elemental calcium daily from calcified algae, often combined with synergistic cofactors. For enhanced efficacy, it is commonly supplemented with 800–1000 IU of vitamin D3 and 45–90 mcg of vitamin K2. The minimum effective dose observed in studies provided around 720 mg elemental calcium daily. To optimize absorption, doses can be divided and taken with meals. The presence of multiple trace minerals and co-administration with vitamins D and K are crucial for maximizing bioavailability. The maximum safe dose is generally consistent with the upper intake levels for total calcium from all sources, typically 2000–2500 mg per day.
FAQs
Is it more effective than traditional calcium supplements?
Evidence suggests algae-based calcium may stimulate osteoblast activity and bone formation more effectively than calcium carbonate or citrate in vitro, potentially leading to better bone health outcomes.
Is it safe for long-term use?
Yes, longitudinal studies lasting up to 7 years have reported that calcified algae powder is safe for long-term use, with no significant adverse effects observed.
How soon can benefits be seen?
Improvements in bone mineral density are gradual and typically become measurable after at least 1 year of consistent daily use, with more significant benefits seen over longer periods.
Does it replace the need for other bone health measures?
No, calcified algae powder should be part of a comprehensive bone health strategy that includes adequate exercise, sufficient vitamin D intake, and other healthy lifestyle choices.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/26885697/ – This 7-year longitudinal trial (Kaats et al., 2016) involving 172 postmenopausal women demonstrated that supplementation with calcified algae powder led to a 7.3% increase in bone mineral density over the study period, with no reported adverse effects, suggesting its safety and efficacy for long-term bone health.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3053489/ – Mehta et al. (2011) conducted in vitro and comparative effectiveness studies showing that algae-based calcium significantly increased osteoblast activity markers (alkaline phosphatase, DNA synthesis, calcium deposition) more than calcium carbonate or citrate, and also reduced oxidative stress in bone cells, providing mechanistic insights into its bone-building potential.
- https://www.clinicaltrials.gov/study/NCT01114685 – This entry on ClinicalTrials.gov (NCT01114685) describes an ongoing or completed Randomized Controlled Trial (RCT) comparing different AlgaeCal formulations with vitamins D3, K, and Mg. While full peer-reviewed results are pending, the study design aims to evaluate BMD improvements, indicating active research into its clinical effectiveness.
- https://www.nutritionaloutlook.com/view/algae-based-calcium-enhances-bone-mineral-density-longitudinal-trial-suggests – This article from Nutritional Outlook discusses the findings of the 7-year longitudinal trial by Kaats et al., highlighting that algae-based calcium supplementation led to significant enhancements in bone mineral density in postmenopausal women, reinforcing its potential as an effective bone health supplement.
- https://www.uclahealth.org/news/article/calcium-supplement-algaecal-can-increase-bone-density – This UCLA Health news article references research suggesting that the calcium supplement AlgaeCal, derived from calcified algae, has the potential to increase bone density. It underscores the growing interest and evidence supporting plant-based calcium sources for skeletal health.