Bovine Hydrolyzed Collagen Proprietary Blend
Also known as: Hydrolyzed collagen, Collagen peptides, Bovine collagen hydrolysate, Bovine Hydrolyzed Collagen
Overview
Bovine Hydrolyzed Collagen is a dietary supplement derived from bovine collagen, primarily type I collagen. It is produced by breaking down collagen into smaller peptides through hydrolysis, enhancing its bioavailability. Primarily used to improve skin health, joint function, and bone density, it is rich in amino acids like glycine, proline, and hydroxyproline, essential for collagen synthesis. Sourced from animal bones and connective tissues, it is available in powder, capsule, and liquid forms. Research indicates moderate evidence supporting its benefits, with systematic reviews and meta-analyses providing strong evidence for skin health improvements. Emerging evidence suggests potential benefits for joint and bone health, warranting further investigation. It is generally considered safe with minimal side effects, making it a popular nutricosmetic and dietary supplement.
Benefits
Bovine Hydrolyzed Collagen primarily benefits skin health by improving hydration, elasticity, and reducing wrinkles. A meta-analysis demonstrated significant improvements in skin hydration and elasticity compared to placebo, with effect sizes of 1.01 (95% CI 0.24, 1.78) for hydration and 1.27 (95% CI 0.19, 2.35) for elasticity. These benefits are primarily observed in women aged 20-70. Emerging evidence suggests potential benefits for joint health and bone density, though more research is needed to confirm these effects. Improvements are typically observed within 90 days of supplementation, highlighting its clinical significance in reducing signs of aging.
How it works
Bovine Hydrolyzed Collagen works by stimulating collagen synthesis, improving skin matrix density, and enhancing joint and bone health through the promotion of matrix molecule production. It interacts with skin, joints, and bones by providing essential amino acids necessary for collagen production. The hydrolyzed form ensures high bioavailability, allowing efficient absorption and utilization by the body. It targets collagen receptors and integrins involved in cell adhesion and matrix synthesis, facilitating the body's natural collagen production processes.
Side effects
Bovine Hydrolyzed Collagen is generally considered safe with minimal side effects. Common side effects are not consistently reported. Uncommon side effects, occurring in 1-5% of individuals, may include mild gastrointestinal upset. Rare side effects, affecting less than 1% of users, may include allergic reactions. No significant drug interactions have been reported. There are no established contraindications, but caution is advised for individuals with severe allergies to bovine products. Pregnant or breastfeeding women should consult healthcare providers before use. Overall, it presents a favorable safety profile when used as directed.
Dosage
The minimum effective dose of Bovine Hydrolyzed Collagen is typically around 5-10 grams per day. Optimal dosage ranges are between 10-20 grams per day for skin health benefits. The maximum safe dose is not well established, but doses up to 20 grams are commonly used without adverse effects. It is best taken with water on an empty stomach for optimal absorption. Hydrolyzed collagen is preferred for its bioavailability. While no specific cofactors are required, vitamin C may enhance collagen synthesis. Adhering to these guidelines ensures effective and safe supplementation.
FAQs
Is Bovine Hydrolyzed Collagen safe?
Generally safe, but consult a healthcare provider if allergic to bovine products.
When is the best time to take it?
Best taken in the morning on an empty stomach for optimal absorption.
How long before I see results?
Improvements in skin health can typically be observed within 90 days of consistent use.
Can it cure joint or bone issues?
It is not a cure for severe joint or bone issues; consult a healthcare provider for severe conditions.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/33742704/ – This systematic review and meta-analysis summarized evidence from 19 clinical trials, indicating that hydrolyzed collagen supplementation improves skin hydration, elasticity, and reduces wrinkles compared to a placebo. The study highlights the potential of hydrolyzed collagen as an effective supplement for improving skin health and reducing signs of aging. The sample included 1,125 participants, primarily women aged 20-70.
- https://www.mdpi.com/2077-0383/13/18/5370 – This systematic review highlights the efficacy and safety of hydrolyzed collagen in improving skin health, particularly in females. It emphasizes the role of collagen supplementation in enhancing skin hydration and elasticity, contributing to overall skin health and appearance. The review consolidates findings from multiple studies, supporting the use of hydrolyzed collagen as a beneficial supplement.
- https://gomitasc3.com/wp-content/uploads/2023/05/Collagen-suplementation-on-skin-aging.pdf – This meta-analysis confirms significant improvements in skin hydration and elasticity with hydrolyzed collagen supplementation. The study provides quantitative evidence supporting the benefits of collagen supplementation on skin aging. The findings reinforce the potential of hydrolyzed collagen as an effective intervention for improving skin health and reducing signs of aging.
- https://orthopedicreviews.openmedicalpublishing.org/article/129086-the-effects-of-type-i-collagen-hydrolysate-supplementation-on-bones-muscles-and-joints-a-systematic-review – This systematic review examines the effects of type I collagen hydrolysate supplementation on bones, muscles, and joints. It synthesizes evidence from multiple studies to assess the potential benefits of collagen supplementation in these areas. The review provides insights into the role of collagen in supporting musculoskeletal health.
- https://www.mdpi.com/2079-9284/12/2/79 – This study investigates the biological pathways through which collagen impacts the body. It explores the mechanisms of action and interactions with various body systems. The research provides a deeper understanding of how collagen supplementation affects overall health and well-being.
Recommended Articles

Top Fertility Supplements for Women in 2025
By 2025, new FDA-approved fertility supplements, emphasizing organic ingredients, have shown significant effectiveness in aiding conception for women in their 30s.

Barcode-Scanner Apps & Supplements: A Reality Check
Barcode-scanner supplement apps vary in accuracy, especially with proprietary blends, but advancements are improving their reliability.

Legal Pre-Workout Supplements for Athletes
Legal pre-workout supplements like those with caffeine, beta-alanine, and creatine can safely enhance athletic performance without failing doping tests.

Top Testosterone Boosters for Cyclists: A Buyer's Guide
For cyclists, choosing testosterone boosters involves finding scientifically-backed, third-party tested products, with top picks including brands like TestoGen and Prime Male.