Bovine Orchic
Also known as: Bovine Orchic, Orchic substance, Orchic extract, Bovine Testicle Extract
Overview
Bovine Orchic is a dietary supplement ingredient derived from the testicular tissue of cattle. It is typically processed into freeze-dried powder or proprietary blends, such as Protomorphogen™ extracts. This ingredient is primarily marketed for its purported benefits in supporting male reproductive function, including testicular health and hormonal balance. It is commonly found in formulations aimed at male fertility, testosterone support, and general reproductive wellness. While it contains peptides, nucleotides, and other biomolecules specific to testicular tissue, there is a significant lack of rigorous clinical research to substantiate its efficacy or mechanism of action. Its use is largely based on traditional practices and proprietary claims rather than evidence-based scientific validation. No standardized chemical characterization or isolated active compounds with established pharmacodynamics have been identified.
Benefits
Bovine Orchic is purportedly used to support male reproductive health and testicular function. However, there is a significant lack of high-quality, peer-reviewed clinical evidence, such as randomized controlled trials (RCTs) or meta-analyses, to substantiate these claims. No statistically significant clinical benefits have been demonstrated in rigorous studies. A systematic review of ingredients in male testosterone and erectile dysfunction supplements found no RCT evidence for bovine orchic, highlighting the absence of clinical data. Therefore, any purported benefits are not supported by scientific research, and there are no documented secondary effects or population-specific benefits with validated efficacy.
How it works
The proposed mechanism of action for Bovine Orchic is largely theoretical. It is hypothesized that peptides and nucleotides derived from bovine testicular tissue might influence endocrine or paracrine signaling pathways related to testicular function. The intention is for it to interact with the male reproductive endocrine system. However, there is no direct scientific evidence, such as mechanistic studies, to confirm these biological pathways or demonstrate bioactivity or specific receptor targets within the human body. Furthermore, information regarding its absorption, bioavailability, and known molecular targets is currently unavailable in the scientific literature.
Side effects
Bovine Orchic is generally considered to have a low risk profile, with no serious adverse effects reported in the available literature or product information. There are no documented common, uncommon, or rare side effects. Similarly, no specific drug interactions or contraindications have been established for its use. However, it is important to note that this assessment is based on a lack of reported incidents rather than comprehensive clinical safety trials. There is no data available regarding its safety for special populations, such as pregnant or lactating women, or children. Due to the limited clinical research, the full safety profile, including potential long-term effects or interactions with specific health conditions, remains largely uncharacterized.
Dosage
There is no established minimum effective dose for Bovine Orchic due to the absence of clinical trials. Commercial products typically recommend dosages ranging from 200 mg to 300 mg of bovine orchic extract per capsule, with general recommendations of 1 to 3 capsules daily, totaling approximately 200 mg to 900 mg per day. These dosages are based on traditional use or proprietary formulations rather than evidence-based guidelines. The maximum safe dose has not been established. Timing considerations for intake, such as on an empty stomach or with food, vary by product. It is commonly available in freeze-dried powder or proprietary blends. Information regarding absorption factors or required cofactors for its efficacy is currently unknown.
FAQs
Is bovine orchic extract proven to increase testosterone?
No, there is no high-quality scientific evidence or clinical trials to support the claim that bovine orchic supplementation increases testosterone levels in humans.
Is it safe to take daily?
Based on traditional use and the absence of reported adverse events, it is generally regarded as safe. However, comprehensive clinical safety data are lacking, so long-term effects are not fully known.
How long before effects are seen?
There are no clinical data available to define the onset of any potential effects, as its efficacy has not been scientifically established.
Is it the same as other testicular extracts?
Bovine Orchic is specifically an extract from bovine testicular tissue. Other testicular extracts may come from different species or have different formulations, potentially leading to different chemical compositions and effects.
Does it have FDA approval?
No, Bovine Orchic is marketed as a dietary supplement ingredient in the U.S. and has not undergone evaluation by the FDA for efficacy or safety.
Research Sources
- https://patents.google.com/patent/WO2004017754A2/en – This patent describes compositions containing freeze-dried bovine tissue blends, including testicular tissue, for various health applications. While it details the composition and potential uses, it does not provide clinical efficacy data or randomized controlled trials to support the claims.
- https://pubmed.ncbi.nlm.nih.gov/32358510/ – This systematic review analyzed ingredients in male testosterone and erectile dysfunction supplements, including 105 randomized controlled trials across 37 ingredients. The review found no RCT evidence specifically for bovine orchic or orchic extracts, assigning low evidence grades to many ingredients due to a significant lack of clinical data.
- https://www.standardprocess.com/products/orchic-pmg – This source describes a proprietary product containing Bovine Orchic, specifically 'Orchic PMG'. It outlines the product's composition and intended uses, which are based on traditional or theoretical claims, but it does not present independent, peer-reviewed clinical validation for its efficacy.
- https://revivemedicalhealth.com/products/standardprocess-orchic-pmg-6175 – This source provides information about a commercial product containing Bovine Orchic, similar to the Standard Process product. It details the product's marketing claims and suggested uses, which are rooted in traditional applications and proprietary formulations, rather than robust clinical research findings.
Supplements Containing Bovine Orchic

Cardio-Plus
SP Standard Process

Trace Minerals-B12
SP Standard Process

Min-Chex
SP Standard Process

Neuroplex
SP Standard Process

Livaplex
SP Standard Process

Male Performance
Ancient Nutrition

A-F Betafood
SP Standard Process

Cardio-Plus
SP Standard Process

Cataplex F
SP Standard Process

Trace Minerals-B12
SP Standard Process

A-F Betafood
SP Standard Process
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