Bovine Uterus Powder
Also known as: bovine uterine tissue powder, Bovine Uterus Powder
Overview
Bovine Uterus Powder is a dried and powdered form of cattle uterine tissue, derived from Bos taurus. It is categorized as an animal-derived reproductive tissue supplement or extract. Historically, it has been investigated in traditional and veterinary contexts for its purported influence on reproductive function, particularly in animal models. The powder contains proteins, extracellular vesicles, and potentially bioactive molecules relevant to uterine physiology. Research into its effects is very limited, consisting mostly of exploratory animal studies, with no robust human clinical trials or systematic reviews available. The quality of evidence is sparse and low, with no high-powered randomized controlled trials or meta-analyses found to support its use or efficacy in humans.
Benefits
There is no robust evidence to support benefits of Bovine Uterus Powder in humans or livestock. One older animal study in rabbits suggested a luteolytic effect (breakdown of the corpus luteum) and an influence on follicular development and progesterone synthesis after intraperitoneal injection. However, this finding has not been replicated, and its relevance to human or livestock fertility enhancement through supplementation is unestablished. Related research on bovine uterine fluid extracellular vesicles explores biomarkers but does not support direct supplementation benefits. No population-specific benefits have been established, and effect sizes or clinical significance have not been quantified in human populations. The existing animal data are limited and mechanistic, with no established time course for any potential effects.
How it works
The precise mechanism of action for Bovine Uterus Powder is not well understood, and most insights come from limited animal studies. It is hypothesized to potentially modulate ovarian function through luteolytic activity, affecting the corpus luteum and progesterone production, as observed in rabbit models. This suggests an interaction with the reproductive endocrine axis, specifically involving the ovary and corpus luteum. Potential molecular targets may include pathways involved in progesterone synthesis and possibly the regulation of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). However, there is no pharmacokinetic data available, so absorption and bioavailability remain unknown.
Side effects
The overall safety profile of Bovine Uterus Powder is largely unknown due to a lack of comprehensive safety data. No common, uncommon, or rare side effects have been documented in any studies. There is no information available regarding potential drug interactions or contraindications. Furthermore, safety in special populations, such as pregnant individuals, children, or those with pre-existing medical conditions, has not been established. The limited animal studies available did not report adverse effects, but these studies were restricted in scope and duration, making it impossible to extrapolate safety to human use. Therefore, the use of Bovine Uterus Powder carries an unknown risk profile.
Dosage
There are no established dosing guidelines for Bovine Uterus Powder. The minimum effective dose, optimal dosage ranges, and maximum safe dose have not been determined for any purpose, either in humans or animals for oral supplementation. Timing considerations for administration are also unknown. The few animal studies that exist utilized the powder in injectable forms (e.g., intraperitoneal injections), and there is no data available for oral dosing. Factors affecting absorption and bioavailability are unknown, and no required cofactors have been documented. Consequently, there is no scientific basis for recommending any specific dosage or method of administration for this product.
FAQs
Is bovine uterus powder effective for fertility?
No, there is no high-quality evidence to support the use of bovine uterus powder for improving fertility in humans or livestock. Research is extremely limited and primarily consists of preliminary animal studies.
Is it safe to consume bovine uterus powder?
The safety of bovine uterus powder has not been systematically evaluated. There is no documented information on common or rare side effects, drug interactions, or contraindications, making its safety profile unknown.
How is bovine uterus powder typically administered?
In the few animal studies conducted, bovine uterus powder was administered via intraperitoneal injections. There is no data or established method for human administration, particularly oral consumption.
Are there more effective alternatives for reproductive benefits?
Yes, phytogenic extracts like Yucca schidigera powder have shown more evidence for reproductive benefits in livestock compared to bovine uterus powder, which lacks robust support.
Does bovine uterus powder modulate hormones?
Limited animal data suggest possible luteolytic effects and influence on progesterone synthesis. However, confirmed hormonal modulation in humans has not been demonstrated or studied.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10209254/ – This experimental study characterized extracellular vesicles found in bovine uterine fluid, identifying them as potential biomarkers for uterine status. However, it did not investigate or provide data on the effects of bovine uterus powder as a supplement or its clinical relevance for fertility enhancement.
- https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2025.1568577/pdf – This review article discusses mechanisms by which various phytogenic extracts can enhance livestock reproduction. While it highlights potential benefits of certain plant-derived compounds, it does not mention or provide any evidence regarding bovine uterus powder's efficacy or role in reproductive enhancement.
- https://pubmed.ncbi.nlm.nih.gov/6068420/ – This older animal study investigated the luteolytic effect of bovine uterine powder in rabbits. It suggested that intraperitoneal injection of the powder could induce luteolysis and affect follicular development and progesterone synthesis. However, the study is limited by its age, small sample size, lack of human data, and absence of full text for detailed review.
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