Breastdefend Herbally Enhanced Mushroom Proprietary Blend
Also known as: BreastDefend Herbally Enhanced Mushroom Proprietary Blend, Turkey Tail, Reishi, Mesima Blend, Coriolus versicolor extract, Trametes versicolor extract, Ganoderma lucidum extract, Phellinus linteus extract, Coriolus versicolor, Ganoderma lucidum, Phellinus linteus Blend
Overview
BreastDefend is a dietary supplement combining extracts from medicinal mushrooms (*Coriolus versicolor*, *Ganoderma lucidum*, *Phellinus linteus*), herbs (*Scutellaria barbata*, *Astragalus membranaceus*, *Curcuma longa*), and nutritional compounds like diindolylmethane (DIM) and quercetin. It is primarily marketed to support breast health, with the aim of inhibiting the growth and spread of breast cancer cells. The formula is designed to target cell-signaling pathways and promote healthy cell behavior. While in vitro and animal studies suggest potential benefits, human clinical trials are limited. The available evidence is primarily based on laboratory and animal studies, indicating a need for more robust human clinical data to confirm its efficacy and safety. It is available in capsule form.
Benefits
BreastDefend has demonstrated the ability to inhibit the proliferation and invasiveness of highly metastatic breast cancer cells in vitro. Animal studies have shown a reduction in breast-to-lung metastasis. Specifically, one animal study showed a significant reduction in metastasis incidence from 67% to 20%. These effects are observed over several weeks in animal models. The supplement may also support immune function and hormone metabolism, although the evidence for these secondary effects is less robust. The benefits are primarily noted in the context of breast cancer prevention and treatment support, but further research is needed to confirm these findings in humans.
How it works
BreastDefend targets cell-signaling pathways involved in cell proliferation and metastasis. It has been shown to downregulate PLAU and CXCR4 genes, which are implicated in cancer progression. The supplement interacts with the immune and endocrine systems to promote healthy cell behavior. The bioavailability of the components, especially the mushroom extracts and DIM, can vary based on formulation and individual metabolism. The formula targets various molecular pathways involved in cancer cell growth and metastasis, aiming to disrupt the processes that allow cancer cells to spread.
Side effects
The overall safety of BreastDefend is considered acceptable based on animal studies at research doses. However, due to limited human studies, the full spectrum of potential side effects is not well-documented. Potential side effects may include gastrointestinal discomfort, although this has not been specifically reported. Rare side effects are unknown due to the lack of extensive human data. There is a potential for interactions with medications affecting liver enzymes or immune function. It is contraindicated for pregnant or nursing women, or those considering pregnancy, without consulting a healthcare provider. Caution is advised for individuals with compromised liver or kidney function.
Dosage
The recommended human dose of BreastDefend is 1 to 4 capsules twice daily. Animal studies have used doses of 100 mg/kg body weight, but this has not been translated to a specific human equivalent dose. It is best to take the supplement with food to enhance absorption. The maximum safe dose has not been established. The capsule form is the most common. Bioavailability may be enhanced with the BCM-95® formulation. Consult with a healthcare provider to determine the appropriate dosage for individual needs.
FAQs
Is BreastDefend safe to use during pregnancy?
No, BreastDefend is contraindicated during pregnancy or nursing without consulting a healthcare provider due to the lack of safety data in these populations.
How should I take BreastDefend for best results?
It is recommended to take 1 to 4 capsules twice daily with food to enhance absorption. Consult with your healthcare provider for personalized advice.
Can BreastDefend replace conventional breast cancer treatment?
No, BreastDefend is not a replacement for medical treatment and should be used under the supervision of a healthcare provider as a complementary therapy.
What are the expected results from taking BreastDefend?
BreastDefend may support breast health by inhibiting cancer cell growth and metastasis, but individual results may vary. It is not a guaranteed cure.
Are there any known drug interactions with BreastDefend?
There is a potential for interactions with medications affecting liver enzymes or immune function. Consult with your healthcare provider to discuss potential interactions.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3583511/ – This in vitro study conducted by Indiana University scientists demonstrated that BreastDefend inhibited the proliferation and invasiveness of highly metastatic breast cancer cells. The research suggests potential mechanisms by which the supplement may exert its effects on breast cancer cells at a cellular level. The study provides a foundation for further research into the efficacy of BreastDefend.
- https://www.themossreport.com/dr-eliaz-breastdefend/ – This article discusses Dr. Isaac Eliaz's formulation of BreastDefend and its potential benefits for breast health. It highlights the combination of medicinal mushrooms, herbs, and nutritional compounds in the supplement. The article emphasizes the importance of using BreastDefend as part of a comprehensive approach to breast cancer prevention and treatment.
- https://pubmed.ncbi.nlm.nih.gov/22842551/ – This study used an orthotopic model of human breast cancer in mice and showed that BreastDefend significantly reduced tumor growth and breast-to-lung metastasis. The findings suggest that BreastDefend may have potential as a complementary therapy for breast cancer. The study provides evidence for the supplement's ability to inhibit the spread of cancer cells in a living organism.
- https://www.themossreport.com/breastdefend/ – This resource provides an overview of BreastDefend, including its ingredients and potential benefits for breast health. It emphasizes the importance of consulting with a healthcare professional before using the supplement. The information is intended to educate consumers about the potential benefits and risks of using BreastDefend.
- https://www.clinicalsynergyformulas.com/products/breastdefend – This is a product page for BreastDefend, providing information on its ingredients, recommended dosage, and potential benefits. It is a commercial source and should be viewed as such. The page also includes information on the manufacturer and how to purchase the product.