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Caloriburn Gp

Also known as: Aframomum melegueta (Grains of Paradise), Grains of Paradise extract, CaloriBurn GP, 6-Paradol, Aframomum melegueta

Overview

CaloriBurn GP is a patented, standardized extract derived from the seeds of Aframomum melegueta, also known as Grains of Paradise, a West African spice. It is used as a thermogenic agent to support weight management by increasing energy expenditure and activating brown adipose tissue (BAT). The extract is standardized to contain 12.5% 6-paradol, a bioactive compound believed to mediate its metabolic effects. Research includes randomized controlled trials (RCTs) demonstrating its effects on energy expenditure and fat metabolism in humans. CaloriBurn GP increases energy expenditure and activates BAT, contributing to increased calorie burning. It may also reduce visceral fat accumulation and improve glucose metabolism. While promising, further research is needed to confirm long-term benefits and safety.

Benefits

CaloriBurn GP offers several potential benefits supported by research. It increases energy expenditure, as demonstrated in a randomized, double-blind, placebo-controlled trial where supplementation resulted in a significant increase in energy expenditure compared to placebo. It also activates brown adipose tissue (BAT), enhancing thermogenic capacity and calorie burning. Studies suggest it can reduce visceral fat accumulation, which is metabolically significant for overweight and obese adults. Additionally, the active compound 6-paradol has shown promise in improving glucose metabolism in animal models. These effects collectively support its role in weight management, although further clinical trials are needed to confirm the magnitude of weight loss benefits.

How it works

CaloriBurn GP primarily works by activating brown adipose tissue (BAT), a specialized fat tissue that dissipates energy as heat, thereby increasing basal metabolic rate and calorie burning. The bioactive compound 6-paradol activates AMP-activated protein kinase (AMPK), a key regulator of energy homeostasis, which enhances glucose uptake and fatty acid oxidation. This process promotes non-shivering thermogenesis, increasing whole-body energy expenditure. Through BAT activation and AMPK signaling, CaloriBurn GP influences lipid metabolism and glucose regulation, contributing to its thermogenic and metabolic effects.

Side effects

Clinical trials report good tolerability of CaloriBurn GP at doses around 40-50 mg/day, with no serious adverse events documented. No significant side effects (>5%) have been reported in available RCTs. However, caution is advised in populations with metabolic disorders until more data are available. Safety in pregnant or breastfeeding women, children, or individuals with chronic diseases has not been established. While no specific drug interactions or contraindications have been identified, it is always prudent to consult with a healthcare professional before starting any new supplement, especially if you have underlying health conditions or are taking medications.

Dosage

The clinically studied dose of CaloriBurn GP is 40-50 mg/day, standardized to 12.5% 6-paradol, as used in human RCTs. It is typically taken with meals to potentially enhance glucose metabolism effects. CaloriBurn GP is available as a standardized extract in capsules or included in multi-ingredient thermogenic supplements. While bioavailability specifics are not detailed, standardization to 6-paradol ensures consistent active compound delivery. It's important to adhere to the recommended dosage and consult with a healthcare professional for personalized advice.

FAQs

How soon can effects be seen?

Increased energy expenditure was observed acutely within 30 minutes and sustained improvements after 5 weeks of supplementation in clinical trials.

Is it safe for long-term use?

Long-term safety data are limited; current evidence supports short-term use without adverse effects at recommended dosages. Consult with a healthcare provider for extended use.

Does it cause jitteriness like caffeine?

No reports indicate stimulant-like side effects commonly associated with caffeine with CaloriBurn GP supplementation.

Can it replace diet and exercise?

CaloriBurn GP is an adjunct to lifestyle interventions, not a substitute for a healthy diet and regular exercise.

Research Sources

https://pmc.ncbi.nlm.nih.gov/articles/PMC10423480/ – This study investigates the effects of Grains of Paradise extract on energy expenditure and brown adipose tissue activation. The research suggests that the extract can increase energy expenditure and activate BAT, potentially aiding in weight management. The study provides evidence for the thermogenic properties of Grains of Paradise.
https://blog.priceplow.com/supplement-news/enhanced-labs-shred – This article discusses the inclusion of CaloriBurn GP in Enhanced Labs Shred, highlighting its role as a thermogenic ingredient. It emphasizes the potential benefits of CaloriBurn GP in increasing energy expenditure and promoting fat loss. The article positions CaloriBurn GP as a key component in a fat-burning supplement.
https://pubmed.ncbi.nlm.nih.gov/40298934/ – This citation links to a study on the effects of Grains of Paradise on metabolic parameters. The research suggests that Grains of Paradise may have beneficial effects on glucose metabolism and body weight regulation. The study provides further support for the potential of Grains of Paradise as a metabolic support ingredient.
https://shop.bodybuilding.com/blogs/nutrition/burn-more-fat-why-signature-shred-should-be-your-1-supplement – This blog post promotes Signature Shred and its fat-burning capabilities, highlighting CaloriBurn GP as a key ingredient. It suggests that CaloriBurn GP can help increase energy expenditure and promote fat loss. The post positions Signature Shred as a top supplement for those looking to burn more fat.
https://www.mdriveformen.com/pages/caloriburn – This page provides information on CaloriBurn GP and its benefits for men's health. It emphasizes the potential of CaloriBurn GP to increase energy expenditure and support weight management. The page positions CaloriBurn GP as a valuable ingredient for men looking to improve their metabolic health.