Caralluma Fimbriata Whole Plant Extract
Also known as: Caralluma, Slimaluma, Caralluma fimbriata
Overview
*Caralluma fimbriata* is a succulent plant native to India and parts of Africa, traditionally utilized for its medicinal properties, particularly in appetite suppression and weight management. The primary application of *Caralluma fimbriata* extract is as a dietary supplement intended to assist in weight reduction and decrease waist circumference. It is characterized by its potential anti-obesity effects, although research findings are mixed. Current evidence comprises various clinical trials alongside limited systematic reviews, suggesting that while some studies report significant impacts on waist circumference, the influence on body weight and metabolic parameters remains less clear.
Benefits
Evidence suggests that the primary benefit of *Caralluma fimbriata* is its ability to reduce waist circumference, a significant factor in central obesity management. A systematic review found a significant reduction of 1.59 cm in waist circumference (95% CI, -3.07 to -0.10, p = 0.041). However, findings regarding body weight or BMI changes are generally not statistically significant. Secondary benefits, such as possible improvements in metabolic syndrome risk factors, are less consistently supported. These benefits appear most pronounced in overweight or obese populations and are typically observed within a few weeks to months of consistent supplementation.
How it works
*Caralluma fimbriata* is believed to exert its appetite-suppressing effects primarily through compounds like pregnane glycosides, although the precise biological mechanisms remain inadequately defined. It may interact with the gastrointestinal system, influencing satiety signals and potentially affecting appetite control. However, more research is needed to elucidate these actions and the molecular targets involved.
Side effects
In general, *Caralluma fimbriata* is considered safe when administered at recommended doses of up to 1000 mg daily for up to 12 weeks. Common side effects can include gastrointestinal disturbances such as constipation, diarrhea, nausea, and rashes. While uncommon or rare side effects are not well-documented, caution is advised in special populations, particularly during pregnancy and breastfeeding due to insufficient safety evidence. Furthermore, no significant drug interactions have been reported.
Dosage
The minimum effective dose for *Caralluma fimbriata* is typically 500 mg, with optimal dosages ranging from 500 mg to 1000 mg per day. The maximum safe dosage is established at 1000 mg daily for a duration of up to 12 weeks. There are no specific timing recommendations for administration, and the supplement is commonly available in capsule or tablet forms. Limited data exists regarding absorption factors related to different formulations.
FAQs
Is it necessary to diet and exercise while taking Caralluma fimbriata?
Yes, combining supplementation with a healthy diet and regular exercise is crucial for maximizing potential benefits.
Is Caralluma fimbriata safe during pregnancy?
No, it is generally advised to avoid *Caralluma fimbriata* during pregnancy and breastfeeding due to lack of safety data.
What results can I expect from taking Caralluma fimbriata?
You may see a potential reduction in waist circumference, though effects on overall body weight can be inconsistent.
Should I take it at a specific time of day?
There are no specific timing recommendations for taking *Caralluma fimbriata*.
Is it a guaranteed weight loss solution?
No, it is not a guaranteed aid for weight loss and should complement traditional weight management approaches.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/34758791/ – A systematic review analyzing *Caralluma fimbriata* as an appetite suppressant found significant reductions in waist circumference and waist-to-hip ratio but noted no significant impact on body weight or metabolic parameters.
- https://pubmed.ncbi.nlm.nih.gov/22191633/ – This pharmacological review discussed the potential anti-obesity properties of *Caralluma* species, focusing on the role of pregnane glycosides and confirmed the GRAS status of *C. fimbriata* as a nutraceutical.
- https://vuir.vu.edu.au/33252/1/ASTELL%20Katie%20-%20Thesis.pdf – A PhD thesis examined the efficacy of *Caralluma fimbriata* in overweight and obese individuals, noting reductions in waist circumference but no significant effects on metabolic syndrome risk factors.
- https://www.webmd.com/vitamins/ai/ingredientmono-1160/caralluma – WebMD provides an overview of *Caralluma fimbriata*, reviewing its use, effectiveness, and side effects based on clinical studies.
- https://onlinelibrary.wiley.com/doi/10.1155/2022/5720372 – This study highlights the effects of *Caralluma fimbriata* in dietary supplementation, particularly observing influences on body weight and waist measurements in clinical settings.