Cardiose Flavonoid Glycoside
Also known as: Flavonoid Glycosides, Cardiac Flavonoids, Plant Flavonoids, Cardiose Flavonoid Glycoside
Overview
Cardiose Flavonoid Glycoside refers to a class of glycosylated plant-derived compounds, known as flavonoids, predominantly found in fruits, vegetables, tea, and wine. They are celebrated for their potent antioxidant and anti-inflammatory properties, contributing significantly to cardiovascular health and overall physiological function. These compounds are essential in managing conditions like atherosclerosis and type 2 diabetes by reducing inflammatory markers. Flavonoids possess diverse structures enhancing their biological activities, characterized by a C2-C3 double bond and hydroxyl groups. Their inclusion in diets or supplements has shown promise in improving cardiovascular function and managing inflammation, supported by various research findings.
Benefits
Flavonoids exhibit numerous health benefits, primarily for cardiovascular health. Systematic reviews demonstrate their ability to significantly lower total cholesterol (TC) by a standardized mean difference of -0.30 (p = 0.0499) and low-density lipoprotein cholesterol (LDLc) by -0.34 (p = 0.01). They also possess anti-inflammatory effects, inhibiting eicosanoid production and reducing pro-inflammatory cytokines like TNF-α and PGE2. Individuals at risk for atherosclerosis and those with type 2 diabetes particularly benefit from regular flavonoid intake, as moderate effect sizes suggest significant clinical relevance. Observations of health improvements often arise from consistent consumption over weeks to months.
How it works
Cardiose Flavonoid Glycosides exert their effects through multiple biological mechanisms. They inhibit the synthesis of inflammatory cytokines and eicosanoids, thereby modulating immune responses and enhancing antioxidant defenses to reduce oxidative stress. Furthermore, they positively influence lipid metabolism by inhibiting cholesterol synthesis enzymes and promoting genes involved in lipid breakdown. Their comprehensive actions reflect beneficial impacts on cardiovascular and immune system health.
Side effects
Generally regarded as safe when consumed within dietary amounts, Cardiose Flavonoid Glycosides can lead to adverse effects at high dosages or with prolonged use. Common side effects, which occur in more than 5% of users, include gastrointestinal disturbances such as nausea and diarrhea. Allergic reactions may occur in 1-5% of users, and severe allergic responses are rare (<1%). Caution is necessary for individuals on blood thinners due to potential bleeding risks. Contraindications exist for those with known allergies to flavonoids or those on certain medications. Pregnant or breastfeeding women should seek medical advice before supplementation.
Dosage
The effective dosage of Cardiose Flavonoid Glycosides varies based on the specific type and health goals. A daily intake of 100-500 mg of flavonoid aglycones is usually recommended for cardiovascular benefits, with optimal doses ranging from 100-1000 mg per day. Though no maximum safe dose is formally established, intakes above 1000 mg daily should be approached with caution due to potential adverse effects. Consistent daily intake is suggested, preferably with meals to enhance absorption. Aglycone forms of flavonoids typically exhibit superior bioavailability, with absorption influenced by dietary fats and fibers.
FAQs
How long does it take to see benefits?
Benefits can typically be observed within several weeks to months of consistent supplementation.
Are flavonoids safe for everyone?
Flavonoids are generally safe, but those with allergies or on certain medications should consult healthcare providers.
Can flavonoids interact with medications?
Yes, particularly with blood thinners, potentially increasing bleeding risk.
What are the common side effects?
Gastrointestinal disturbances are the most commonly reported side effects.
When should I take flavonoids?
Consistent daily intake is recommended, preferably with meals to enhance absorption.
Supplements Containing Cardiose Flavonoid Glycoside
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