Get Your Personalized Supplement StackSupplement Stack Quiz

Catuaba Bark

Also known as: Catuaba, Catiguá, Tatuaba, Trichilia catigua

Overview

Trichilia catigua, commonly known as Catuaba, is a plant native to South America, particularly Brazil. Its bark has been used in traditional medicine for its purported effects on enhancing sexual arousal, improving memory, and reducing fatigue. The bark contains several active compounds, including flavalignans, flavan-3-ols, and flavonoids, which contribute to its antioxidant properties. Catuaba is often consumed as a hydroalcoholic extract. While it is marketed as an adaptogen, the scientific evidence supporting its benefits in humans is limited. Most of the available research is preclinical, involving animal studies and in vitro experiments. Therefore, further human trials are needed to validate its efficacy and safety.

Benefits

The primary benefits of Catuaba bark, primarily observed in animal models, include antinociceptive (pain relief) and antioxidant effects. Studies have shown that Catuaba extracts can reduce pain sensations and combat oxidative stress. There is also some evidence suggesting potential antifatigue and pro-memory effects in rodents. Some rodent studies also suggest potential antidepressant effects. However, these benefits have not been consistently demonstrated in human trials, and the effect sizes and clinical significance remain uncertain. More research is needed to determine the specific conditions or populations that may benefit most from Catuaba supplementation.

How it works

The mechanism of action of Catuaba bark is not fully understood, but research suggests that its antinociceptive effects may involve dopaminergic pathways in the central nervous system (CNS). The antioxidant activity is attributed to the presence of flavonoids and other polyphenols, which can neutralize free radicals and reduce oxidative stress. Catuaba may interact with the CNS to exert its potential antidepressant effects, although the specific molecular targets are not well-defined. Further research is needed to fully elucidate the biological pathways and interactions with body systems.

Side effects

Due to limited human studies, the safety profile of Catuaba bark is not well-established. Common, uncommon, and rare side effects are not well-documented. Drug interactions have not been thoroughly studied. As a precaution, Catuaba is contraindicated during pregnancy and breastfeeding due to the lack of safety data in these populations. It is essential to exercise caution and consult with a healthcare professional before using Catuaba, especially if you have pre-existing health conditions or are taking other medications. More comprehensive safety assessments are needed to fully characterize the potential risks associated with Catuaba supplementation.

Dosage

The minimum effective dose, optimal dosage ranges, and maximum safe dose of Catuaba bark have not been established for humans. Animal studies have used doses ranging from 25 to 300 mg/kg. Catuaba is typically used as a hydroalcoholic extract. Timing considerations and absorption factors are not well-studied. Due to the lack of human data, it is difficult to provide specific dosage recommendations. It is crucial to consult with a healthcare professional to determine an appropriate and safe dosage based on individual health status and potential risks.

FAQs

What is Catuaba bark used for?

Catuaba bark is traditionally used for enhancing sexual arousal, improving memory, and reducing fatigue. However, scientific evidence supporting these uses in humans is limited, and more research is needed.

Is Catuaba bark safe to use?

Due to limited human studies, the safety profile of Catuaba bark is not well-established. It is contraindicated during pregnancy and breastfeeding. Consult with a healthcare professional before use.

How should I take Catuaba bark?

There are no established dosage guidelines for Catuaba bark in humans. It is typically used as a hydroalcoholic extract. Consult with a healthcare professional for personalized recommendations.

Does Catuaba bark really enhance sexual performance?

Catuaba bark is often believed to enhance sexual performance, but scientific evidence supporting this claim is lacking. More research is needed to determine its effects on sexual function.

Are there any known side effects of Catuaba bark?

Due to limited human studies, the side effects of Catuaba bark are not well-documented. It is essential to exercise caution and consult with a healthcare professional before using Catuaba.

Research Sources

https://pmc.ncbi.nlm.nih.gov/articles/PMC3095233/ – This 2011 study demonstrated that Trichilia catigua hydroalcoholic extract has antinociceptive effects in mouse models, suggesting potential pain relief benefits. The study indicates that the extract may act through dopaminergic pathways to reduce pain sensation.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6686118/ – This 2018 study found that T. catigua extracts exhibit antioxidant and anticholinesterase activity, and reduce fatigue in rodent models. The research suggests that the extracts may have potential benefits in reducing oxidative stress and improving cognitive function.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5987406/ – This review highlights the general need for more rigorous research on natural supplements, including those like catuaba. It emphasizes the importance of systematic reviews and human trials to fully understand the benefits and risks of such supplements.
https://pubmed.ncbi.nlm.nih.gov/30896252/ – This study investigates the effects of catuaba on preventing stress-related behaviors in mice. The findings suggest that catuaba may have potential as a preventative measure against stress-induced behavioral changes.
https://www.webmd.com/vitamins/ai/ingredientmono-396/catuaba – This WebMD page provides general information about catuaba, including its uses and potential side effects. It serves as a basic overview but lacks the depth of peer-reviewed research.