Catuaba Bark Extract
Also known as: Catuaba, Trichilia catigua
Overview
Catuaba is a plant native to Brazil, with its bark traditionally used for its purported medicinal properties. It is often marketed as a supplement to enhance sexual arousal, improve memory, and alleviate anxiety. However, scientific evidence supporting these uses is limited. The primary research on catuaba focuses on its potential antidepressant and antinociceptive effects, primarily observed in animal models. Catuaba extracts are typically prepared as hydroalcoholic solutions. The quality of available evidence is generally low due to a lack of rigorous clinical trials in humans. Therefore, caution is advised when considering catuaba for medicinal purposes, and consultation with a healthcare provider is recommended.
Benefits
Limited evidence suggests catuaba may have antidepressant-like effects, potentially mediated by dopamine pathways, as indicated by animal studies. It has also demonstrated antinociceptive activity in animal models, suggesting potential pain-relieving properties. Anecdotal evidence suggests improvements in memory and reduced fatigue, but these claims lack substantial scientific support. No specific population benefits have been clearly established, and the available studies do not provide sufficient data to quantify effect sizes or clinical significance in humans. Further research is needed to validate these potential benefits and determine their clinical relevance.
How it works
Catuaba's potential antidepressant effects may be related to its interaction with dopaminergic pathways in the brain. Its antinociceptive action could involve multiple neurotransmitter systems, contributing to pain relief. The extract interacts with the central nervous system (CNS) to produce these effects. However, the specific molecular targets and mechanisms of action are not yet clearly identified. Further research is needed to fully elucidate how catuaba interacts with the body's systems at a molecular level, including absorption and bioavailability.
Side effects
Due to limited research, the overall safety profile of catuaba is not well-established. Common, uncommon, and rare side effects are not well-documented. Drug interactions have not been thoroughly studied, and caution is advised when combining catuaba with other medications or supplements. Catuaba is contraindicated in pregnancy and breastfeeding due to a lack of safety data. Individuals with pre-existing medical conditions should consult a healthcare provider before using catuaba. More comprehensive research is needed to fully understand the potential adverse effects and safety considerations associated with catuaba use.
Dosage
Effective and safe dosage ranges for catuaba have not been established due to limited research. There is no established minimum effective dose, optimal dosage range, or maximum safe dose. Timing considerations and form-specific recommendations are not well-studied, although it is typically used as a hydroalcoholic extract. Absorption factors and required cofactors are also not well-understood. Due to the lack of scientific evidence, it is crucial to consult with a healthcare provider before using catuaba to determine appropriate and safe usage guidelines.
FAQs
What are the purported benefits of catuaba?
Catuaba is often claimed to enhance sexual arousal, improve memory, and reduce anxiety. However, these claims are not well-supported by scientific evidence. Limited research suggests potential antidepressant and antinociceptive effects, primarily in animal models.
Is catuaba safe to use?
There is insufficient reliable information to assess the safety of catuaba when taken orally. It is contraindicated in pregnancy and breastfeeding due to a lack of safety data. Consult a healthcare provider before use, especially if you have pre-existing medical conditions.
How should catuaba be taken?
Due to the lack of scientific evidence, there are no established dosing guidelines for catuaba. It is typically used as a hydroalcoholic extract, but optimal dosage ranges, timing considerations, and form-specific recommendations are not well-studied.
Does catuaba really enhance sexual performance?
Catuaba is often believed to enhance sexual performance, but this claim is not well-supported by scientific research. A systematic review on herbal supplements for erectile dysfunction did not specifically evaluate catuaba due to a lack of relevant clinical trials.
Where can I find reliable information about catuaba?
Consult with a healthcare provider or refer to reputable sources such as PubMed and WebMD. Be cautious of anecdotal claims and prioritize information from peer-reviewed studies and systematic reviews when available.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3095233/ – This study evaluated the antinociceptive effects of *Trichilia catigua* hydroalcoholic extract in mice. The results showed significant pain relief in several models, suggesting potential analgesic properties. The mechanisms may involve dopaminergic pathways, indicating a possible neurological component to its pain-relieving effects.
- https://pubmed.ncbi.nlm.nih.gov/15991001/ – This study found that catuaba extract exhibits antidepressant-like effects in animal models, possibly mediated by dopamine pathways. The research suggests a potential mechanism for mood-enhancing effects. However, the study lacks human data and rigorous clinical trial design, limiting its applicability to human health.
- http://sif2022-production.s3.amazonaws.com/uploads/attachment/file_it/1788/Borrelli_2018_Drugs.pdf – This is a systematic review on herbal supplements for erectile dysfunction. While catuaba is sometimes used for sexual performance, the review did not specifically evaluate catuaba due to a lack of relevant clinical trials. The review highlights the need for more rigorous research to validate the efficacy of herbal supplements for sexual dysfunction.
- https://www.webmd.com/vitamins/ai/ingredientmono-396/catuaba – WebMD provides general information on catuaba, including its uses, potential side effects, and precautions. It notes that there is insufficient evidence to rate the effectiveness of catuaba for many of its purported uses. The information serves as a general reference but should be supplemented with more rigorous scientific evidence.
- https://www.verywellhealth.com/the-benefits-of-catuaba-88652 – Verywell Health discusses the potential benefits of catuaba, including its purported effects on sexual function and mood. The article acknowledges the limited scientific evidence supporting these claims. It emphasizes the importance of consulting with a healthcare provider before using catuaba, especially for individuals with pre-existing health conditions.
Supplements Containing Catuaba Bark Extract

BZRK Red VooDoo Punch
Black Magic

BZRK Blue VooDoo Punch
Black Magic

Passion Rx
Advance Physician Formulas

Passion Rx with Yohimbe
Advance Physician Formulas

Safeguard
Chaotic Labz

Catuaba Alcohol Free
Hawaii Pharm

Muira Puama and Catuaba Alcohol Free
Hawaii Pharm

Catuaba
Hawaii Pharm

Catuaba Extract
Herbadiet

Muira Puama and Catuaba
Hawaii Pharm

Masculini-T
LifeSeasons

Libido
DaVinci Laboratories