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Celery Juice Powder

Also known as: Celery, celery seed, celery juice powder, Apium graveolens

Overview

Celery juice powder is a dried, powdered form of the Apium graveolens plant, including its seeds, used as a dietary supplement. It is primarily investigated for its potential benefits in cardiovascular and metabolic health, particularly concerning blood pressure regulation, glycemic control, lipid profile improvement, and body composition. The supplement is characterized by its antioxidant, anti-inflammatory, and potential antimicrobial properties, attributed to bioactive compounds like flavonoids and phthalides. Research on celery juice powder is ongoing, with a moderate level of maturity, including several randomized controlled trials (RCTs) and recent meta-analyses. While evidence quality varies, some studies suggest moderate to high-quality evidence for certain effects, though heterogeneity and methodological limitations in existing research are noted. It is generally considered to have a favorable safety profile.

Benefits

Celery juice powder offers several evidence-based benefits, primarily in metabolic and cardiovascular health. A meta-analysis of 8 RCTs involving 473 participants demonstrated that celery preparations significantly reduce systolic blood pressure, with a standardized mean difference of -1.0 (95% CI: -1.85 to -0.14; p=0.022). This effect is supported by moderate to high-quality evidence, particularly when derived from celery seeds and used in interventions shorter than 30 days. The same meta-analysis also indicated improvements in hyperglycemia parameters and hyperlipidemia markers, suggesting broader metabolic benefits, though the clinical significance of these effects can vary. Furthermore, a pilot RCT involving 36 overweight/obese individuals with type 2 diabetes found that 750 mg of celery powder daily significantly reduced body fat percentage (p=0.021). In vitro studies also highlight celery seed extracts' ability to inhibit various pathogens and modulate adipocyte-related gene expression, pointing to potential antimicrobial and anti-inflammatory properties, though these require clinical validation.

How it works

Celery's beneficial effects are attributed to its rich content of bioactive compounds, including flavonoids (such as apigenin), phthalides, and phenolic acids. These compounds contribute to its mechanism of action through several pathways. They are believed to induce vasodilation by relaxing vascular smooth muscle and improving endothelial function, which helps to reduce blood pressure. The antioxidant properties of these compounds help to mitigate oxidative stress, a key factor in metabolic syndrome. Additionally, specific bioactive molecules within celery seed extracts have been shown to inhibit microbial growth by targeting bacterial cell functions. The absorption and bioavailability of these compounds can vary depending on the preparation method, with powder forms generally retaining many active components, though processing can influence their efficacy.

Side effects

Celery juice powder and its extracts generally exhibit a favorable safety profile, with clinical trials and meta-analyses reporting no significant difference in adverse events compared to placebo. Mild side effects, such as occasional gastrointestinal discomfort and increased urination, have been reported but are infrequent. No serious adverse effects or significant drug interactions have been consistently observed in high-quality clinical trials. However, caution is advised for individuals with a known celery allergy, as allergic reactions can occur. Furthermore, individuals taking antihypertensive medications should exercise caution due to the potential for additive blood pressure-lowering effects, which could lead to hypotension. It is always recommended to consult a healthcare professional before starting any new supplement, especially if you have pre-existing conditions or are on medication.

Dosage

Effective dosages of celery preparations in clinical trials vary, with celery powder typically used at around 750 mg daily. For celery seed extracts, specific dosages can differ. Research suggests that shorter-term interventions, particularly those under 30 days, may show more pronounced effects on blood pressure. While an optimal standardized dosage is still being established, the 750 mg/day dose of celery powder has been used in studies demonstrating benefits such as body fat reduction. The timing of administration, such as with meals, and co-administration with other compounds like antioxidants, may influence absorption, but these factors are not yet well-studied. There are no clearly defined upper limits or safety thresholds established for celery juice powder, but adherence to studied dosages is recommended.

FAQs

Is celery juice powder effective for hypertension?

Yes, moderate evidence, particularly from celery seed extracts and short-term use, supports its effectiveness in reducing systolic blood pressure.

Are there safety concerns with celery juice powder?

Generally, it is safe with mild, infrequent side effects. However, individuals with celery allergy or those on antihypertensive medications should exercise caution.

How long does it take to see effects from celery juice powder?

Some benefits, particularly blood pressure reduction, have been observed within 30 days of use. Longer-term effects require further research.

Does celery juice powder help with weight loss?

Limited evidence from a pilot study suggests it may help reduce body fat percentage in overweight/obese individuals with type 2 diabetes, but more research is needed.

Research Sources

https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1597680/full – This meta-analysis of 8 RCTs (n=473) found that celery preparations significantly reduced systolic blood pressure (SMD −1.0; p=0.022) and improved glycemic and lipid profiles. The evidence quality was moderate to high, but heterogeneity was noted. The study concluded a favorable safety profile, but highlighted the need for more research to address heterogeneity and potential biases.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10494649/ – This double-blind, placebo-controlled pilot RCT (n=36) in overweight/obese type 2 diabetes patients investigated the effects of 750 mg/day celery powder. It found a significant reduction in body fat percentage (p=0.021) but no significant changes in other cardiometabolic parameters. The small sample size limits the generalizability of these findings.
https://journals.sagepub.com/doi/full/10.1177/1934578X251325063 – This review summarizes in vitro and mechanistic studies on celery, demonstrating its antimicrobial activity against various pathogens and its ability to modulate adipocyte gene expression. These preclinical findings suggest potential metabolic and anti-infective properties, but emphasize the need for clinical validation to confirm these effects in humans.