Certified Organic Agrimony Extract
Also known as: Agrimonia pilosa, Agrimony, Common Agrimony, Hairy Agrimony, Agrimonia eupatoria
Overview
Agrimony, scientifically known as *Agrimonia eupatoria*, is a perennial herb native to Europe and Asia, traditionally utilized in folk medicine to address various ailments, including sore throats and abdominal pain. Its extract, often consumed in herbal tea form, is recognized for potential health benefits attributed to the presence of flavonoids, tannins, and phenolic acids. Modern research primarily explores its antioxidant, anti-inflammatory, and hepatoprotective properties. Despite emerging studies, the overall research maturity remains limited, with most evidence stemming from in vitro and animal studies rather than robust human clinical trials. Current findings suggest a need for further exploration of its efficacy and potential therapeutic applications.
Benefits
Clinical studies indicate that agrimony exhibits hepatoprotective effects, with one double-blind trial revealing significant reductions in liver enzymes ALT and AST among participants. Additionally, agrimony demonstrates antioxidant properties, with evidence of increased plasma total antioxidant capacity and decreased inflammation markers. Animal studies hint at potential anti-diabetic benefits, showing improvements in insulin sensitivity. In vitro studies suggest antiviral activity against SARS-CoV-2. However, concrete conclusions regarding specific populations are limited, and while some findings are promising, further investigation is needed to establish definitive efficacy and clinical significance.
How it works
Agrimony's primary mechanism of action involves antioxidant and anti-inflammatory pathways, likely through the inhibition of TLR-4 signaling. Through the reduction of oxidative stress, it aids in liver protection and inflammation management. The flavonoids and phenolic acids present in agrimony interact with various cellular targets, promoting its antioxidant effects. While the exact biological pathways require further elucidation, initial findings indicate a potential influence on glucose metabolism, offering implications for diabetes management.
Side effects
Agrimony is generally considered safe, but data on adverse effects remains limited due to a lack of extensive clinical trials. Common side effects are not well-documented; however, instances of photodermatitis have been reported. There are no well-documented drug interactions, but caution is advised against use during pregnancy or lactation due to insufficient safety data. Individuals with pre-existing liver conditions should approach with care, considering its hepatoprotective properties. The rarity of severe side effects has been noted, but thorough safety evaluations are warranted.
Dosage
Recommended dosages for agrimony are not firmly established. Traditional use involves brewing tea from 1g of dried aerial parts per 200mL of water, typically consumed twice daily. Clinical trials indicate an average dosage of 160mg/day of a standardized extract, yet optimal dosage ranges remain poorly defined. The maximum safe dosage and factors affecting absorption may vary based on the formulation, emphasizing the need for patient-specific adjustments and adherence to guidance until more conclusive dosing recommendations emerge.
FAQs
What are the common uses of agrimony?
Agrimony is commonly used for liver health, as a diuretic, and to relieve sore throat and abdominal pain.
Is agrimony safe during pregnancy?
It is advised to avoid agrimony during pregnancy and lactation due to a lack of safety data.
How should agrimony be taken?
Agrimony is typically consumed as a tea or in capsule form, often taken twice daily.
What should I expect from using agrimony?
Potential benefits include improved liver health and enhanced antioxidant status, although results may vary.
Is there a standard dosage for agrimony?
There is no established standard dosage; traditional use suggests 1g of dried aerial parts per 200mL of water.
Research Sources
- https://www.drugs.com/npp/agrimony.html – This source provides an overview of agrimony, discussing its uses, effects, and the importance of more clinical research. It mentions traditional uses and potential health benefits alongside possible limitations in current evidence.
- https://pubmed.ncbi.nlm.nih.gov/36177633/ – The article presents a randomized, double-blind, placebo-controlled trial evaluating the hepatoprotective effects of agrimony. Key findings indicate significant reductions in liver enzymes, highlighting the potential therapeutic applicability.
- https://www.mdpi.com/1420-3049/20/11/19715 – This in vitro study showcases agrimony's antiviral properties, particularly against SARS-CoV-2. While promising, the results underscore the necessity for additional research to verify in vivo efficacy.
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