Chamomile Flowering Head Extract
Also known as: Matricaria chamomilla, Chamomile, German Chamomile
Overview
Chamomile, scientifically known as *Matricaria chamomilla*, is a widely recognized herb derived from its flowering heads. It is commonly consumed as a tea, extract, or used topically. Chamomile is primarily known for its calming and sleep-aiding properties, making it a popular choice for individuals seeking natural remedies for anxiety and insomnia. The herb contains flavonoids and apigenin, which are believed to contribute to its therapeutic effects. Research suggests that chamomile can improve sleep quality, reduce anxiety symptoms, and possess anti-inflammatory properties. It is available in various forms, including dried flowers, tea bags, liquid extracts, capsules, and topical creams. Chamomile is sourced from various regions worldwide, with Germany being a prominent producer.
Benefits
Chamomile offers several evidence-based benefits. It significantly improves sleep quality, particularly by reducing the number of awakenings after sleep onset, as supported by multiple studies. For individuals with Generalized Anxiety Disorder (GAD), chamomile has demonstrated efficacy in reducing anxiety symptoms. Some studies also suggest that chamomile may alleviate inflammation, particularly in conditions like Irritable Bowel Syndrome (IBS). Furthermore, it has shown potential in reducing oral mucositis and alleviating anxiety and depression in cancer patients. Clinical trials have reported significant improvements in GAD symptoms with mean differences of -1.43 and -1.79 after 2 and 4 weeks, respectively. The benefits for sleep and GAD are typically observed within weeks of consistent use. However, more large-scale randomized controlled trials (RCTs) are needed to further validate these effects.
How it works
Chamomile's mechanism of action primarily involves its active compounds, flavonoids and apigenin, interacting with GABA receptors in the brain. This interaction promotes relaxation and reduces anxiety by modulating neurotransmitter activity in the central nervous system. While the exact molecular targets are not fully understood, GABA receptors and possibly serotonin receptors are believed to be involved. The bioavailability of chamomile's active compounds is not well-studied, but they are thought to be absorbed through the gastrointestinal tract after ingestion. This modulation of the GABAergic system contributes to chamomile's calming and anxiolytic effects.
Side effects
Chamomile is generally considered safe for most individuals, but some side effects and precautions should be noted. Allergic reactions are possible, especially in individuals with allergies to plants in the Asteraceae family (e.g., ragweed, marigolds, chrysanthemums). These reactions are rarely severe but can include skin rashes, itching, or difficulty breathing. Mild gastrointestinal disturbances, such as nausea or stomach upset, have been reported in some cases. Anaphylaxis is an extremely rare but potentially life-threatening side effect. Chamomile may interact with sedatives and blood thinners due to its sedative and antiplatelet effects, so caution is advised when combining it with these medications. It is contraindicated in pregnancy and breastfeeding due to a lack of sufficient safety data. Overall, chamomile is well-tolerated when used as directed, but individuals should be aware of potential allergic reactions and drug interactions.
Dosage
The typical minimum effective dose of chamomile extract is 200-400 mg per day. For sleep and anxiety, optimal dosage ranges are between 400-800 mg daily. While a maximum safe dose is not well-defined, doses above 1,000 mg are rarely used. For sleep benefits, it is best taken before bedtime. Chamomile is commonly available in capsules or teas. The bioavailability of chamomile may be enhanced with fatty meals, although this has not been extensively studied. There are no known required cofactors for chamomile to be effective. It is important to start with a lower dose and gradually increase it to assess tolerance and effectiveness. Consult with a healthcare professional before starting chamomile, especially if you have underlying health conditions or are taking medications.
FAQs
Is chamomile safe to use with other medications?
Chamomile may interact with sedatives and blood thinners. Consult your healthcare provider before use, especially if you are taking other medications, to avoid potential adverse effects.
Can I take chamomile if I am pregnant or breastfeeding?
Chamomile is not recommended for pregnant or breastfeeding women due to a lack of sufficient safety data. It is best to avoid use during these periods to ensure the safety of both mother and child.
When is the best time to take chamomile for sleep?
For sleep benefits, it is best to take chamomile about 30-60 minutes before bedtime. This allows the calming effects to take place as you are preparing to sleep, promoting better sleep quality.
How long does it take to see the benefits of chamomile?
Benefits for sleep and anxiety are typically observed within a few weeks of consistent use. Individual results may vary, but regular use is important to experience the full effects of chamomile.
Is chamomile a cure for anxiety disorders?
Chamomile is not a cure for severe anxiety disorders but can be a useful adjunct to other treatments. It may help reduce anxiety symptoms and promote relaxation, but it should not replace professional medical advice or treatment.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/31006899/ – This study is a systematic review and meta-analysis that investigates the efficacy of chamomile for sleep quality and generalized anxiety disorder (GAD). The findings suggest that chamomile significantly improves sleep quality and reduces GAD symptoms, indicating its potential as a natural remedy for these conditions. The study provides quantitative data supporting the benefits of chamomile, making it a valuable resource for understanding its clinical applications.
- https://onlinelibrary.wiley.com/doi/10.1002/ptr.6349 – This systematic review examines the effects of chamomile on various health conditions. The review highlights that chamomile can reduce oral mucositis in cancer patients and may decrease anxiety and depression. The study underscores the potential of chamomile as a supportive therapy for cancer patients, offering insights into its anti-inflammatory and mood-enhancing properties.
- https://www.mdpi.com/1424-8247/15/10/1284 – This paper reviews the diverse applications of chamomile, focusing on its anti-inflammatory, antioxidant, and antimicrobial properties. It discusses the traditional uses of chamomile and the scientific evidence supporting its health benefits. The review emphasizes the potential of chamomile in treating various ailments, highlighting its versatility as a medicinal herb.
- https://journals.sagepub.com/doi/full/10.1177/15347354231164600 – This research article investigates the impact of chamomile on anxiety and depression, particularly in specific populations. The study provides evidence that chamomile can be beneficial in reducing anxiety and depression symptoms in certain contexts. The findings contribute to the growing body of literature supporting the use of chamomile as a natural remedy for mental health conditions.
- https://pubmed.ncbi.nlm.nih.gov/39106912/ – This meta-analysis evaluates the effects of chamomile on sleep parameters. The study demonstrates that chamomile improves sleep by reducing awakenings after sleep onset, although it does not significantly affect sleep onset latency. The results suggest that chamomile is effective in enhancing sleep quality by promoting more continuous sleep, making it a valuable option for individuals with sleep disturbances.
Recommended Articles

Avoiding Stimulants: A Guide for Sensitive Individuals
Identify stimulant ingredients to avoid, understand their effects, discover alternatives, and learn label-reading tips for sensitivity.

Top Sleep Aids for Quality Rest Without Grogginess
Melatonin, valerian root, and chamomile improve sleep without causing grogginess.

Herbal Supplements & Prenatal Vitamins: What to Avoid
Certain herbal supplements can negatively interact with prenatal vitamins and are not recommended during pregnancy due to risks.

Top Sleep Supplements of 2025: Efficacy & Safety
2025's sleep supplements with new ingredients like herbal extracts and amino acids show significant efficacy and safety.