ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Hydrolyzed Chicken Bone Broth Collagen Concentrate

Also known as: Hydrolyzed collagen, collagen peptides, chicken bone broth collagen, collagen hydrolysate, Hydrolyzed Chicken Bone Broth Collagen Concentrate

Overview

Hydrolyzed Chicken Bone Broth Collagen Concentrate is a dietary supplement derived from chicken bone broth through enzymatic hydrolysis, which breaks down collagen into smaller, more bioavailable peptides. It primarily contains Type I and Type II collagen peptides, including specific sequences like Gly-Pro-Hyp and Hyp-Gly. This supplement is widely used for its potential benefits in skin health, promoting anti-aging effects, improved hydration, and elasticity. It also offers support for joint and bone health, and aids in muscle maintenance. The hydrolysis process enhances its absorption and utilization in the body, making it an effective nutricosmetic and musculoskeletal support supplement. Research, including randomized controlled trials and meta-analyses, supports its efficacy, particularly for skin benefits, with moderate to high-quality evidence.

Benefits

Oral supplementation with hydrolyzed collagen, including chicken-derived sources, significantly improves skin hydration, elasticity, and reduces wrinkles, typically observed after 8–12 weeks of consistent use. Meta-analyses consistently show statistically significant improvements compared to placebo, with robust effect sizes for skin moisture and elasticity. These benefits are particularly well-documented in middle-aged to older adults, predominantly women. While the evidence is stronger for skin health, some studies suggest benefits for joint pain reduction and bone health, especially in osteopenic postmenopausal women. However, results for musculoskeletal benefits are less consistent and show higher study heterogeneity. Clinical significance is noted with p < 0.05 across multiple studies for skin parameters, indicating meaningful improvements.

How it works

Hydrolyzed collagen peptides are efficiently absorbed in the gastrointestinal tract and then distributed throughout the body. These peptides, particularly specific di- and tri-peptides like Gly-Pro-Hyp, act as signaling molecules. They stimulate fibroblast activity, which is crucial for the synthesis of new collagen and other extracellular matrix components in the skin and connective tissues. Additionally, these peptides may help reduce the activity of matrix metalloproteinases, enzymes responsible for collagen degradation, thereby slowing down the breakdown of existing collagen. The hydrolysis process enhances the bioavailability of these peptides, allowing them to cross intestinal barriers more effectively and exert their systemic effects.

Side effects

Hydrolyzed collagen supplements are generally considered safe with a low incidence of adverse effects reported in clinical trials. The most common side effects, though rare, include mild gastrointestinal discomfort such as bloating or a feeling of fullness. No significant drug interactions have been documented, and there are no known contraindications for its use. While specific risks for pregnant or lactating women have not been identified, it is always advisable for these populations to consult a healthcare provider before starting any new supplement. Overall, the safety profile is favorable, and doses up to 10 grams daily are typically well tolerated.

Dosage

The minimum effective dose for hydrolyzed collagen peptides ranges from 1 to 10 grams per day. For optimal skin benefits, a daily dosage of 2.5 to 10 grams is typically recommended, to be taken consistently for at least 8–12 weeks. While a maximum safe dose has not been definitively established, doses up to 10 grams daily have been shown to be well tolerated in studies. The timing of supplementation is flexible, as absorption is not significantly impacted by food intake. Co-supplementation with Vitamin C may enhance collagen synthesis, potentially improving the efficacy of the collagen peptides.

FAQs

Is hydrolyzed chicken bone broth collagen as effective as other collagen sources?

Yes, evidence suggests chicken-derived collagen peptides, rich in type II collagen, are effective for skin and joint health, comparable to bovine or fish sources.

How soon can results be expected?

Improvements in skin health, such as hydration and elasticity, typically become noticeable after 6–12 weeks of consistent daily supplementation.

Are there any risks?

Hydrolyzed collagen is generally safe with minimal side effects, primarily mild gastrointestinal discomfort in rare cases. No significant drug interactions are known.

Does it help with joint pain?

Some evidence suggests benefits for joint pain, particularly when combined with other joint-supporting nutrients, though research is less conclusive than for skin benefits.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC10773595/ – This systematic review and meta-analysis of 14 RCTs, involving 967 participants, found significant improvements in skin hydration and elasticity after 12 weeks of hydrolyzed collagen supplementation. The study included various collagen sources, noting overall high-quality evidence for skin benefits despite some heterogeneity in sources.
  • https://pubmed.ncbi.nlm.nih.gov/33742704/ – This systematic review and meta-analysis of 19 RCTs, involving 1125 participants, focused on skin aging outcomes. It reported statistically significant reductions in wrinkles and improvements in skin elasticity and hydration after 90 days of hydrolyzed collagen supplementation, primarily in women aged 20–70 years.
  • https://www.nmi.health/collagen-a-review-of-clinical-use-and-efficacy/ – This review discusses the clinical use and efficacy of collagen hydrolysate, including chicken-derived peptides. It highlights an RCT (n=64) showing improved skin hydration and elasticity after 12 weeks, emphasizing that peptide composition, particularly Gly-Pro-Hyp content, influences efficacy.
  • https://orthopedicreviews.openmedicalpublishing.org/article/129086-the-effects-of-type-i-collagen-hydrolysate-supplementation-on-bones-muscles-and-joints-a-systematic-review – This systematic review evaluated the effects of type I collagen hydrolysate on bones, muscles, and joints. It found potential benefits in bone mineral density in postmenopausal women with osteopenia but cautioned about study heterogeneity and methodological limitations across the included research.

Recommended Articles

Milk Thistle & Liver Health: The Role of Silymarin

Milk Thistle & Liver Health: The Role of Silymarin

Silymarin in milk thistle significantly supports liver health by providing antioxidant properties and therapeutic effects on liver diseases.

Boost Brain Health: Key Ingredients for Aging

Boost Brain Health: Key Ingredients for Aging

Omega-3 fatty acids, Vitamin E, and curcumin are key ingredients that support cognitive function in aging, alongside the Mediterranean and MIND diets.

Best Ingredients for Kidney Health & Function

Best Ingredients for Kidney Health & Function

Foods high in antioxidants, omega-3 fatty acids, and following diets like the DASH and Mediterranean are crucial for kidney health.

Mushroom Supplement Extraction: Enhancing Potency

Mushroom Supplement Extraction: Enhancing Potency

Extraction is essential to unlock the full potency of certain mushroom supplements like Reishi, Cordyceps, and Lion's Mane.