Chinese Smilax Extract
Also known as: Chinese Smilax, Baqia, Smilax china L.
Overview
Smilax china L., commonly known as Chinese Smilax or Baqia, is a plant widely used in traditional Chinese medicine. It is primarily recognized for its anti-inflammatory and antimicrobial properties, leading to its use in treating conditions such as inflammatory disorders, pelvic inflammatory disease, and arthritis. The plant contains compounds like quercetin and resveratrol, known for their antioxidant effects. Research on Smilax china L. focuses on its ethnopharmacological properties and potential cosmetic applications due to its antimicrobial and antioxidant activities. However, the evidence supporting its benefits is limited, with most studies being observational or in vitro experiments. Further randomized controlled trials (RCTs) are needed to validate its efficacy and safety.
Benefits
Smilax china L. is traditionally used for its anti-inflammatory and antimicrobial properties, which may be beneficial in treating conditions like acne and pelvic inflammatory disease. However, the clinical significance of these effects is not well-established due to the lack of rigorous clinical trials. It has also been used for energy enhancement, treating impotency, seminal disorders, and arthritis, but these uses are primarily based on traditional medicine rather than strong scientific evidence. The plant contains compounds like quercetin and resveratrol, which are known for their antioxidant and anti-inflammatory properties, but their specific effects in Smilax china L. extracts require further investigation.
How it works
Smilax china L. contains compounds such as quercetin and resveratrol, which are known for their antioxidant and anti-inflammatory properties. These compounds may interact with various biological pathways to exert their effects. The plant's extracts may influence immune responses and skin health through their antimicrobial activity. However, specific molecular targets and mechanisms of action are not well-documented for Smilax china L. extracts. Further research is needed to understand how the plant's components are absorbed, metabolized, and interact with body systems.
Side effects
The safety profile of Smilax china L. is not well-established due to the lack of comprehensive clinical trials. While it is generally considered safe when used traditionally, potential side effects and drug interactions are not well-documented. Caution is advised in pregnant or breastfeeding women due to the lack of safety data. Potential interactions with other medications are not well-studied. Users should consult healthcare professionals before using Smilax china L. supplements due to the lack of comprehensive safety and efficacy data. More research is needed to identify potential adverse effects and contraindications.
Dosage
Due to the limited clinical evidence, there is no established minimum effective dose, optimal dosage range, or maximum safe dose for Smilax china L. Timing considerations, form-specific recommendations, absorption factors, and required cofactors are also not established. Users should consult healthcare professionals before using Smilax china L. supplements due to the lack of comprehensive safety and efficacy data. Further research is needed to determine appropriate dosing guidelines and safety thresholds.
FAQs
Is Smilax china L. safe to use?
Safety data are limited, and potential interactions with medications are not well-studied. Consult a healthcare professional before use, especially if pregnant, breastfeeding, or taking other medications.
How should I take Smilax china L.?
There is no established timing or administration protocol. Consult a healthcare professional for personalized advice based on your health status and any other medications you are taking.
What are the expected benefits of Smilax china L.?
The expected benefits are based on traditional use rather than clinical evidence. Consult a healthcare professional to understand potential benefits and risks based on your specific condition.
Are there any misconceptions about Smilax china L.?
It is often assumed to be safe and effective without adequate clinical evidence. Always consult a healthcare professional and rely on evidence-based information.
Why is there limited research on Smilax china L.?
The plant is more commonly used in traditional medicine, and rigorous clinical trials are lacking. More research is needed to validate its efficacy and safety through randomized controlled trials.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/37541403/ – This study investigates the protective effects of Smilax china L. rhizome extract against TNF-α-induced inflammation in HaCaT cells. The extract inhibits the expression of pro-inflammatory mediators and reduces oxidative stress, suggesting potential therapeutic applications for inflammatory skin diseases. The research provides insights into the anti-inflammatory mechanisms of Smilax china L. at the cellular level.
- https://www.mdpi.com/1420-3049/27/23/8331 – This study focuses on the antimicrobial activity of Smilax china L. root extracts against Cutibacterium acnes, suggesting potential use in cosmetics. The in vitro results indicate that the extracts can inhibit bacterial growth, which could be beneficial for treating acne. However, the study did not involve human subjects, and further research is needed to confirm these findings in vivo.
- https://www.mdpi.com/2311-7524/10/8/850 – This study presents a comparative analysis of Smilax china L. extracts, highlighting variations in phytochemical content and antioxidant potential based on extraction methods. The research demonstrates that different extraction techniques can yield extracts with varying levels of bioactive compounds and antioxidant activity. This study did not assess clinical outcomes, focusing instead on the chemical composition and antioxidant properties of the extracts.
- https://onlinelibrary.wiley.com/doi/10.1155/2021/5552532 – This review of Smilax china L.'s ethnopharmacology notes its traditional use in treating inflammatory disorders and other health conditions. The review highlights the plant's historical applications in traditional medicine and its potential therapeutic properties. However, it does not provide quantitative clinical evidence, emphasizing the need for further research to validate its efficacy.
- https://academicjournals.org/journal/AJPP/article-full-text/AEBBD4361954 – This study investigates the effects of Smilax china on hematological and biochemical parameters in rats. The results indicate that Smilax china extract can influence blood cell counts and liver enzyme levels. The study provides insights into the potential physiological effects of Smilax china, but further research is needed to determine its relevance to human health.
Supplements Containing Chinese Smilax Extract
Recommended Articles

Top Energy Boosters: Caffeine, B12, Adaptogens
Caffeine, B12, and adaptogens are key for energy, with new 2025 substances offering promising benefits.

Ashwagandha Liver Risk: 2025 Safety Update
Recent findings suggest a potential link between ashwagandha use and liver injury, highlighting the need for caution.

Is Buying High-Dose Berberine Overseas Safe?
Buying high-dose berberine from overseas involves risks such as adverse effects, legal issues, and variable safety standards.

Berberine vs. Metformin: Glucose Control Efficacy
Clinical trials show berberine can effectively control glucose levels, comparable to metformin, with a different side effect profile.