Cistanche Deserticola Ma
Also known as: Desert Ginseng, Rou Cong Rong, Cistanche deserticola
Overview
*Cistanche deserticola* Ma is a parasitic plant utilized in traditional Chinese medicine, widely recognized for its purported health benefits such as anti-aging, immune modulation, and support for gastrointestinal health. This herb is native to the Alxa region of northwest China and is composed of various bioactive compounds, particularly phenylethanol glycosides. These compounds are associated with its pharmacological benefits. Though interest in this herb has grown, the overall research maturity level remains moderate, revealing a promising yet incomplete understanding of its efficacy and mechanisms in humans. Many studies report varying methodologies and levels of rigor, necessitating further exploration to substantiate its traditional uses with robust scientific evidence.
Benefits
Evidence supports several key benefits of *Cistanche deserticola*, notably: 1. **Constipation Relief**: Studies indicate that polysaccharides derived from *C. deserticola* can enhance intestinal motility and positively alter gut microbiota, demonstrating a significant effect in alleviating constipation. 2. **Anti-Aging**: Research using senescence-accelerated mice shows that *C. deserticola* extracts may extend lifespan by counteracting immunosenescence, which may be particularly beneficial for elderly populations. Additionally, some preliminary studies suggest potential neuroprotective effects and immune function enhancement, particularly in the elderly. However, the precise effect sizes in human studies remain less well documented.
How it works
*Cistanche deserticola* functions through several biological pathways. Its polysaccharides enhance the integrity of intestinal tight junctions and influence gut microbiota composition, crucial for gastrointestinal health. Additionally, it may counteract immunosenescence by promoting the restoration of naive T cells and lowering the levels of inflammatory cytokines. Although its phenylethanol glycosides are recognized as key active components, specific molecular targets and their interactions in the body systems are not thoroughly elucidated. The data on its absorption and bioavailability in humans remains limited.
Side effects
While generally considered safe, comprehensive safety data in human subjects is limited. Commonly reported side effects are not well-documented, but gastrointestinal upset has been noted in some individuals taking herbal supplements. There is a potential for allergic reactions and interactions with other medications affecting gastrointestinal or immune function. Specific contraindications include pregnancy and breastfeeding due to insufficient safety data. Furthermore, elderly or immunocompromised individuals should consult with healthcare providers prior to consumption to mitigate any possible risks.
Dosage
An established dosage for humans is not well-defined, as most dosing guidelines stem from animal studies, which range from 100 to 2500 mg/kg. Timing for administration is generally flexible as no specific recommendations are available; the plant is typically consumed in forms such as tea or capsules. Absorption may be influenced by individual gut health, and currently, there are no documented requirements for co-factors. Safe upper limits and maximum doses in human applications remain undetermined.
FAQs
Is *Cistanche deserticola* safe to use?
Generally considered safe when used appropriately, but comprehensive safety data in humans is lacking. Always consult a healthcare provider.
What are the expected results from using *Cistanche deserticola*?
Results may vary widely among individuals; benefits are more consistently noted in elderly populations.
Can I take *Cistanche deserticola* with other medications?
Yes, but it's advisable to consult a healthcare provider to avoid potential interactions, especially with drugs affecting gut or immune health.
What form is *Cistanche deserticola* available in?
*Cistanche deserticola* is typically available as tea or capsules.
Is *Cistanche deserticola* a substitute for medical treatment?
No, it should not be seen as a substitute for medical treatment; consult a healthcare provider for appropriate medical advice.
Research Sources
- https://e-century.us/files/ajtr/16/11/ajtr0159017.pdf – This study investigates the role of CDPS from *Cistanche deserticola* in alleviating constipation by improving gut motility and microbiota modulation. The findings are primarily based on animal models, which shows potential but limits direct applicability to humans.
- https://pubmed.ncbi.nlm.nih.gov/38876007/ – This research outlines the anti-aging effects of extracts from *Cistanche deserticola*, highlighting lifespan extensions in senescence-accelerated mice and mechanisms involved in antagonizing immunosenescence. However, results may not be directly translatable to humans.
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.782962/full – A review summarizing various pharmacological effects of *Cistanche deserticola*, including its neuroprotective and immune-modulating properties. The review emphasizes the need for further human studies to confirm the benefits observed.
- https://pubmed.ncbi.nlm.nih.gov/36992906/ – This article discusses the immune modulatory effects of *Cistanche deserticola*, positing its ability to enhance naive T cell levels and reduce pro-inflammatory cytokines.
- https://onlinelibrary.wiley.com/doi/10.1155/2014/601383 – This study provides insights into the chemical composition and pharmacological effects of *Cistanche deserticola*, stressing the importance of thorough research to ascertain its health benefits and mechanisms of action.