Citrus Reticulata Extract
Also known as: Mandarin orange extract, Citrus reticulata extract, Citrus reticulata
Overview
Citrus reticulata extract, derived from the mandarin orange, is rich in flavonoids and bioactive compounds known for their antioxidant properties. This extract has gained attention for its potential benefits in managing dyslipidemia and aiding in weight management. Although evidence is emerging, studies reveal mixed results concerning its efficacy. Generally, the extract is noted for its high flavonoid content, contributing to its health-promoting characteristics. It is typically used in dietary supplements aimed at improving cardiovascular health and weight management. The extract is available in various forms, including capsules and powders, yet substantial evidence supporting its effectiveness is still required.
Benefits
Research indicates that Citrus reticulata extract may help in weight reduction and improve lipid profiles by decreasing total cholesterol, LDL, and triglyceride levels, while increasing HDL cholesterol. Notably, individuals with dyslipidemia or those seeking weight loss may find these benefits particularly relevant. However, the effects vary widely across studies, and clinical significance is not consistently demonstrated. For instance, a recent randomized controlled trial (RCT) showed a decrease in body weight and waist circumference, but no significant alterations in other lipid parameters were recorded. Overall evidence remains mixed, necessitating further targeted studies to validate these findings.
How it works
Citrus reticulata extract is thought to exert its effects primarily through the flavonoids it contains, which may influence lipogenesis and beta-oxidation processes, thus modulating lipid metabolism. The interaction with the cardiovascular system could lead to improved lipid profiles and potential aid in weight management. Research suggests that these flavonoids target enzymes related to lipid metabolism, although specific pathways remain to be thoroughly elucidated.
Side effects
Citrus reticulata extract is generally recognized as safe when consumed in moderation, with no extensive documentation on adverse effects. Most individuals tolerate it well, although sensitive persons may experience gastrointestinal discomfort. Uncommon or rare side effects are not well-established, and any side effects are typically mild. Although drug interactions are not well-studied, caution is advisable with medications affecting blood lipids or blood pressure. Allergies to citrus fruits could also present a risk, calling for careful consideration. Pregnant or breastfeeding individuals should consult healthcare providers before initiating supplementation with this extract.
Dosage
Though specific dosing guidelines for Citrus reticulata extract are lacking, general recommendations for citrus extracts typically range from 0.5 to 1 gram daily. Since minimum effective doses have not been established, optimal dosages remain uncertain. There are no specific guidelines for timing; however, consuming these extracts along with fatty meals may enhance bioavailability. No maximum safe dose has been officially determined at this time, and it is available in several formulations, including capsules and powders. Overall, consistency in usage may yield better results.
FAQs
What should I consider before starting Citrus reticulata extract?
Consulting with a healthcare provider before beginning any new supplement regimen is essential, especially for those with existing medical conditions or who are pregnant or breastfeeding.
Is Citrus reticulata extract safe?
Generally deemed safe in moderate amounts, but long-term effects and potential interactions with medications are not well documented.
When is the best time to take this supplement?
No specific timing is recommended; consistency in daily intake may enhance potential benefits.
What results can I expect from using this extract?
Results may vary; some studies show benefits in weight loss and improving lipid profiles, but inconsistent outcomes are noted.
Can I replace medical treatment with Citrus reticulata extract?
It should not be considered a substitute for medical treatment or a balanced diet; consult a healthcare provider for appropriate guidance.
Research Sources
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.822678/full – This randomized controlled trial assessed the effects of Citrus reticulata extract on healthy individuals with a BMI ≥ 24 kg/m2, noting a decrease in body weight and waist circumference over 8 weeks. However, other parameters such as body fat and lipid profiles showed no significant changes.
- https://aquafishcrsp.oregonstate.edu/aquafish-nop – Research on different citrus species, highlighting the relevant potential benefits of citrus extracts in weight and metabolic management, is underscored in this citation.
- https://academic.oup.com/nutritionreviews/article/82/9/1292/7272715?login=false – A systematic review and meta-analysis emphasized that citrus extracts, including *Citrus reticulata*, might reduce total cholesterol, LDL, and triglycerides, while increasing HDL. However, considerable heterogeneity among studies was observed, suggesting a need for more consistent research.
- https://www.science.gov/topicpages/i/inverse+variance+meta-analysis.html – The importance of statistical methods, including meta-analysis for evaluating efficacy of dietary interventions like citrus extracts, is highlighted, underscoring the need for better quality data.
- https://www.researchgate.net/publication/358606871_Citrus_Extract_as_a_Perspective_for_the_Control_of_Dyslipidemia_A_Systematic_Review_With_Meta-Analysis_From_Animal_Models_to_Human_Studies – This systematic review discusses the role of citrus extracts in managing dyslipidemia, synthesizing findings from animal and human studies, and suggesting potential applications for cardiovascular health.
Supplements Containing Citrus Reticulata Extract

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