Clerodendrum Phlomidis
Also known as: Clerodendrum phlomidis Linn. f., Clerodendrum multiflorum (Burm.f) O. Kuntze, Volkameria multiflorum Burm. f., Clerodendrum phlomidis
Overview
Clerodendrum phlomidis is a plant species belonging to the Lamiaceae family, traditionally used in Ayurveda and Siddha medicine. It's known for its potential anti-inflammatory, antidiabetic, antioxidant, and antimicrobial properties, primarily attributed to the presence of flavonoids, terpenoids, and other bioactive compounds. Traditionally, it has been used to manage conditions such as inflammation, diabetes, nervous disorders, asthma, rheumatism, digestive disorders, and urinary disorders. While experimental studies suggest promising bioactivities, the current evidence is largely based on traditional use and in vitro/in vivo studies. Human trials are limited, highlighting the need for more rigorous clinical research to validate its efficacy and safety.
Benefits
Experimental studies suggest that Clerodendrum phlomidis possesses antioxidant, anti-inflammatory, antidiabetic, and antimicrobial activities. These findings are primarily based on in vitro and in vivo studies, indicating potential health benefits. Traditional medicine also suggests benefits for digestive disorders, asthma, and rheumatism; however, these uses lack robust clinical validation. The absence of large-scale human trials makes it difficult to quantify effect sizes or determine clinical significance. Further research is needed to confirm these benefits and establish the plant's efficacy in specific populations.
How it works
Clerodendrum phlomidis is believed to exert its effects through multiple biological pathways, primarily involving antioxidant and anti-inflammatory mechanisms. The plant's bioactive compounds, such as flavonoids and terpenoids, may interact with the immune and metabolic systems to modulate these pathways. However, the precise molecular targets and mechanisms of action are not well-defined. Further research is needed to elucidate the specific interactions and bioavailability of its active constituents within the body.
Side effects
Based on traditional use, Clerodendrum phlomidis is generally considered safe. However, formal toxicity studies are limited, and comprehensive data on side effects are lacking. Common, uncommon, and rare side effects are not well-documented. Drug interactions have not been studied, and contraindications are not established. Due to the limited safety data, caution is advised, especially for pregnant and lactating women. Further research is needed to fully assess the safety profile of Clerodendrum phlomidis.
Dosage
Due to the limited research, there are no established dosing guidelines for Clerodendrum phlomidis. The minimum effective dose, optimal dosage ranges, and maximum safe dose have not been determined. Traditional use involves whole plant extracts, but specific timing considerations and form-specific recommendations are lacking. Absorption factors have not been studied, and required cofactors are not identified. Without further research, it is difficult to provide specific dosage recommendations.
FAQs
Is Clerodendrum phlomidis safe?
It is generally considered safe based on traditional use, but formal toxicity studies are limited. More research is needed to fully assess its safety profile.
What are the benefits of Clerodendrum phlomidis?
Experimental studies suggest antioxidant, anti-inflammatory, antidiabetic, and antimicrobial activities. Traditional medicine suggests benefits for digestive disorders, asthma, and rheumatism, but clinical validation is needed.
How should I take Clerodendrum phlomidis?
There are no established dosing guidelines. Traditional use involves whole plant extracts, but specific timing and form-specific recommendations are lacking.
Are there any drug interactions?
Drug interactions have not been studied. Caution is advised if taking other medications.
Research Sources
- https://pub.iapchem.org/ojs/index.php/admet/article/view/2442 – This review highlights the plant's traditional use and experimental evidence for various bioactivities, including antioxidant, anti-inflammatory, and antidiabetic effects. It notes a lack of systematic studies on bioactive fractions and pure compounds, indicating a need for more focused research.
- https://www.electricveg.com/lamiaceae.html – This source provides general information about the Lamiaceae family, to which Clerodendrum phlomidis belongs. It offers context on the plant's classification and relationship to other plants within the family.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11661801/ – This article discusses the traditional uses of Clerodendrum phlomidis in Ayurveda and Siddha medicine. It emphasizes the need for more rigorous clinical trials to validate these uses and understand the plant's efficacy and safety in humans.
- https://siddhacouncil.com/ccrs/wp-content/uploads/2021/05/ccrs_publication-1.pdf – This publication from the Central Council for Research in Siddha provides insights into the traditional applications of Clerodendrum phlomidis within the Siddha system of medicine. It underscores the importance of further research to substantiate these traditional uses with scientific evidence.
- https://pubmed.ncbi.nlm.nih.gov/20550872/ – This study focuses on the phytochemical properties of Clerodendrum phlomidis, identifying various compounds such as flavonoids and terpenoids. These compounds are believed to contribute to the plant's bioactive properties, although further research is needed to understand their specific mechanisms of action.
