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CoffeeBerry

Q: Does CoffeeBerry improve cognitive function or mood?

Current high-quality evidence does not support cognitive or mood benefits; one RCT showed increased mental fatigue and decreased cognitive accuracy.

Q: Is CoffeeBerry safe?

It appears safe in short-term use at studied doses, with no serious adverse effects reported in clinical trials.

Q: How quickly does it work?

Effects, both positive and negative, have been measured acutely within 1-2 hours post-dose.

Q: Can it aid weight loss?

Evidence for weight loss is primarily from green coffee bean extract studies, which are different and have inconsistent results.

Q: Is caffeine content a concern?

Caffeine is present but in lower amounts than coffee beans; caffeine-sensitive individuals should exercise caution.

Also known as: CoffeeBerry, Coffee fruit extract, Coffea arabica fruit extract

Overview

CoffeeBerry is a concentrated extract derived from the whole fruit of the *Coffea arabica* plant, encompassing the skin and pulp, distinguishing it from traditional coffee bean extracts. It is rich in polyphenols, particularly chlorogenic acids (CGAs), and contains a small amount of caffeine. Marketed primarily for its purported cognitive enhancement, mood improvement, and antioxidant support, CoffeeBerry is also sometimes suggested for weight management. While it contains bioactive compounds believed to influence brain function and metabolism, the research supporting these claims is emerging and limited. High-quality clinical trials specifically on CoffeeBerry extract are scarce, with more data available on green coffee bean extracts, making the overall evidence base sparse and mixed.

Benefits

Current high-quality evidence does not robustly support significant benefits for CoffeeBerry. A 2023 randomized controlled trial (RCT) involving 72 participants found that 100 mg of CoffeeBerry extract did not improve mood or cognitive performance. Instead, it was associated with an increase in mental fatigue and a decrease in accuracy on a rapid visual information processing task at 60 minutes post-dose. No significant mood or psychological benefits were observed in this study, and there is no evidence to suggest benefits for any specific population subgroup. While the observed negative effects were statistically significant, their clinical relevance remains uncertain. Evidence for weight loss benefits is primarily associated with green coffee bean extract, not CoffeeBerry, and these studies often have methodological limitations and inconsistent results.

How it works

CoffeeBerry contains bioactive compounds such as chlorogenic acids and caffeine. Caffeine is known to modulate neurotransmitter systems, including dopamine and acetylcholine, and acts as an adenosine receptor antagonist, which can lead to mild central nervous system stimulation. Chlorogenic acids contribute to the extract's antioxidant properties and may influence glucose metabolism. The combined action of these compounds is thought to interact with the body's systems by potentially reducing oxidative stress and providing mild stimulant effects. Chlorogenic acids have moderate bioavailability, while caffeine is rapidly absorbed, allowing for acute effects to be observed.

Side effects

CoffeeBerry appears to be generally well tolerated in short-term use at studied doses. A 2023 randomized controlled trial reported no serious adverse events related to the treatment. Common side effects, defined as occurring in over 5% of participants, were not specifically attributed to CoffeeBerry in this study, though some unrelated events like headache and tiredness were noted. Uncommon (1-5%) and rare (<1%) side effects have not been reported. Due to its caffeine content, potential interactions with other CNS stimulants or medications metabolized by cytochrome P450 enzymes should be considered. Contraindications include caffeine sensitivity. Caution is advised for pregnant and lactating individuals due to a lack of specific safety data in these populations.

Dosage

The minimum effective dose for CoffeeBerry has not been established, as a 100 mg dose in one RCT showed no benefit and some negative effects. Consequently, optimal dosage ranges and maximum safe doses are currently unknown. Acute effects have been measured within 1-2 hours post-dose, suggesting that timing considerations would be relevant for immediate impact. CoffeeBerry is typically administered as a standardized extract in capsule or powder form. Absorption of its components, particularly caffeine, is rapid, though it may be influenced by food intake. No specific cofactors are identified as being required for its efficacy.

FAQs

Does CoffeeBerry improve cognitive function or mood?

Current high-quality evidence does not support cognitive or mood benefits; one RCT showed increased mental fatigue and decreased cognitive accuracy.

Is CoffeeBerry safe?

It appears safe in short-term use at studied doses, with no serious adverse effects reported in clinical trials.

How quickly does it work?

Effects, both positive and negative, have been measured acutely within 1-2 hours post-dose.

Can it aid weight loss?

Evidence for weight loss is primarily from green coffee bean extract studies, which are different and have inconsistent results.

Is caffeine content a concern?

Caffeine is present but in lower amounts than coffee beans; caffeine-sensitive individuals should exercise caution.

Research Sources

https://pmc.ncbi.nlm.nih.gov/articles/PMC10254646/ – This randomized controlled trial investigated the acute effects of 100 mg CoffeeBerry extract on cognitive performance and mood in 72 healthy adults. The study found that CoffeeBerry did not improve mood or cognitive function; instead, it increased mental fatigue and decreased accuracy on a rapid visual information processing task at 60 minutes post-dose. The findings suggest a lack of cognitive or mood benefits and highlight potential negative acute effects.
https://pmc.ncbi.nlm.gov/articles/PMC2943088/ – This systematic review examined the efficacy of green coffee extract for weight loss. It concluded that green coffee extract might modestly reduce body weight, but the evidence is weak due to methodological flaws in the included trials, such as poor blinding, small sample sizes, short durations, and potential conflicts of interest. This review is relevant for distinguishing CoffeeBerry from green coffee extract and understanding the limitations of weight loss claims.
https://www.journalofexerciseandnutrition.com/index.php/JEN/article/view/202 – This source, though not fully detailed in the provided text, refers to an RCT on *Coffee arabica* seed extract. The summary indicates that no clear cognitive or mood benefits were reported, and the study likely suffered from insufficient details and a small sample size, leading to a low to moderate quality assessment. It further supports the general lack of robust evidence for cognitive benefits from coffee-derived extracts.