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Coffeeberry Whole Coffee Fruit Extract

Also known as: Coffeeberry Whole Coffee Fruit Extract, Whole Coffee Fruit Concentrate (WCFC), Coffee Cherry Pulp Extract (CBP), Coffea arabica extract

Overview

Coffeeberry Whole Coffee Fruit Extract is derived from the fruit of the coffee plant, specifically the pulp and skin of the coffee berry, from *Coffea arabica*. It is rich in polyphenols, particularly chlorogenic acid, procyanidins, and a variety of antioxidants, making it a potent herbal extract and antioxidant supplement. This extract is lower in caffeine than traditional coffee beans and has gained attention for potential benefits in neuroprotection, weight management, and skin health. Emerging research includes animal studies demonstrating its effects on metabolic health, while some human trials have suggested increases in brain-derived neurotrophic factor (BDNF), although more extensive human studies are needed for conclusive evidence.

Benefits

The primary evidence-based benefits of Coffeeberry Whole Coffee Fruit Extract include significant increases in brain-derived neurotrophic factor (BDNF) levels, which can enhance neuroprotection, particularly in older adults. A notable study documented a 143% increase in BDNF after a 100mg dose. Additionally, the extract exhibits strong antioxidant activity, shown by significant DPPH and superoxide dismutase (SOD) activities, which help combat oxidative stress. Animal studies indicate its potential for weight management and metabolic health improvements, revealing anti-obesity and anti-diabetic effects. Though there is emerging evidence suggesting cardiovascular and immune health benefits, more research is required to understand these effects in human populations.

How it works

Coffeeberry extracts work through several biological pathways, primarily by scavenging free radicals and reducing oxidative stress, which promotes antioxidant activity. The extracts modulate metabolic processes by enhancing the activity of AMP-activated protein kinase (AMPK) and influencing glucose and lipid metabolism. Additionally, the elevation of BDNF levels indicates potential support for neurogenesis and protection against neurodegenerative disorders, particularly beneficial in aging populations.

Side effects

Coffeeberry Whole Coffee Fruit Extract is generally regarded as safe. However, limited safety data in humans exists. Common side effects remain unidentified due to insufficient data, while animal studies suggest potential gastrointestinal issues at high doses. Caution is advised for individuals with dietary restrictions or pre-existing conditions. Potential drug interactions may occur, particularly with medications affecting blood sugar and blood pressure, necessitating careful monitoring. Pregnant individuals should approach with caution due to limited safety data. If symptoms such as gastrointestinal discomfort arise, it is advisable to cease use and consult a healthcare professional.

Dosage

The recommended dosage for Coffeeberry Whole Coffee Fruit Extract can vary, with studies indicating effective doses starting from 100mg for benefiting BDNF increases. Research has utilized doses ranging from 100mg to several grams daily, though optimal dosage ranges are not clearly established. There is no specific timing for administration indicated in the literature, and forms prepared through multistep extraction methods may yield higher antioxidant capacities compared to simpler powder forms. While a maximum safe dose remains undefined, caution with high doses is recommended, especially in light of animal study findings indicating potential adverse effects at elevated levels.

FAQs

Is Coffeeberry Whole Coffee Fruit Extract safe?

Generally safe, but high doses may pose risks. Long-term effects in humans need further study.

How should I take Coffeeberry Extract?

No specific timing is recommended; consult a healthcare provider for tailored advice.

What benefits can I expect?

Increased BDNF levels and potential antioxidant and metabolic benefits, though more research in humans is needed.

Can I use it instead of medication?

No, it is a supplement that may offer additional benefits but not a substitute for prescribed treatments.

Research Sources

https://www.mdpi.com/2076-3921/13/1/10 – This study highlights the antioxidant and metabolic effects of coffeeberry extracts, showing significant anti-hyperlipidemic effects in mouse models. It underscores the promising antioxidant activity and implications for metabolic health.
https://drperlmutter.com/coffee-fruit-concentrate-and-brain-cells/ – A human trial investigating the effects of coffee fruit concentrate on BDNF levels, finding a significant 143% increase in participants, suggesting potential neuroprotective benefits but limited by sample size.
https://www.nutritionaloutlook.com/view/study-compares-higher-antioxidant-coffee-fruit-extract-coffee-powder – This analytical study compared different extraction methods of coffee fruit, showing that multistep extraction processes yield higher CGA content and antioxidant capacity, providing insights into effective supplement formulations.
https://www.webmd.com/diet/what-to-know-about-coffee-fruit – Provides a general overview of coffee fruit and its potential health benefits, including antioxidant properties and neuroprotective effects, but indicates the need for more comprehensive human studies.
https://www.futureceuticals.com/coffeeberry – Offers insights on Coffeeberry extract, discussing its health implications, including antioxidant benefits and emerging research on its effects on metabolism and neuroprotection.