ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Dark Rage Proprietary Pump And Total Performance Complex

Also known as: Dark Rage, MHP Dark Rage, Dark Rage Proprietary Pump and Total Performance Complex

Overview

Dark Rage is a branded pre-workout formula by MHP designed to enhance muscle pumps, workout intensity, endurance, and muscle growth. It is a proprietary complex that claims to stimulate erythropoietin (EPO) release alongside nitric oxide (NO) pathways to increase blood volume and vasodilation, thereby improving oxygen and nutrient delivery to muscles. The formula also contains well-known ergogenic aids such as creatine, beta-alanine, branched-chain amino acids (BCAAs), arginine, and AAKG (arginine alpha-ketoglutarate). This product aims to surpass traditional NO-based pumps by incorporating EPO-stimulating agents (ESAs), which are purported to increase red blood cell production and blood volume, enhancing muscle performance and delaying fatigue. It is marketed primarily for bodybuilding and athletic performance enhancement, focusing on 'pump,' power, endurance, and recovery.

Benefits

The primary claimed benefits of Dark Rage include enhanced muscle pump through a combination of increased blood volume (via purported EPO stimulation) and vasodilation (via NO pathways), improved muscle endurance, and delayed fatigue due to better oxygen delivery. It also supports muscle growth by increasing nutrient delivery and fostering an anabolic environment. Secondary effects may include increased workout intensity and power output. This supplement is specifically targeted at resistance-trained athletes and bodybuilders seeking enhanced muscle pumps and performance. However, there are no independent peer-reviewed clinical trials specifically evaluating the proprietary complex or its unique EPO-stimulating mechanism. The claims rely on theoretical mechanisms and ingredient-level evidence for components like creatine, beta-alanine, and arginine, which have established benefits for strength, power, and endurance. Acute effects on pumps and performance are expected during workouts, while muscle growth benefits would require chronic supplementation.

How it works

Dark Rage's mechanism of action is based on several pathways. It primarily claims to stimulate erythropoietin (EPO), which is purported to increase red blood cell production and blood volume, thereby enhancing oxygen transport capacity and muscle perfusion beyond what NO-mediated vasodilation alone can achieve. Secondly, it aims to boost nitric oxide (NO) production via ingredients like arginine and AAKG, leading to vasodilation and increased blood flow to muscles. Additionally, the complex includes other ergogenic agents: creatine supports ATP regeneration, beta-alanine buffers muscle acidity to delay fatigue, and BCAAs support muscle protein synthesis. These ingredients interact with the cardiovascular system (affecting blood volume and flow), the muscular system (improving oxygen and nutrient delivery), and metabolic pathways (enhancing energy production and fatigue resistance). Standard oral bioavailability is expected for the included amino acids and creatine, but specific data on the proprietary ESA compounds are not available.

Side effects

No independent safety data specific to the proprietary EPO-stimulating compounds or the full Dark Rage complex have been found in peer-reviewed literature. While individual ingredients like creatine, beta-alanine, arginine, and BCAAs generally have well-established safety profiles at recommended doses, the safety of the proprietary blend, particularly its claimed EPO-stimulating effects, remains unverified. Potential theoretical risks could include excessive vasodilation leading to hypotension or cardiovascular strain, especially if EPO stimulation is significant, but this is speculative without clinical data. There are no documented drug interactions or contraindications specific to this complex. However, individuals with pre-existing conditions such as cardiovascular disease, hypertension, or erythropoietic disorders should exercise caution due to the theoretical risks associated with unverified EPO stimulation. Users should be aware that the lack of specific safety data for the proprietary blend means its long-term effects are unknown.

Dosage

The exact dosing of the proprietary complex within Dark Rage is not publicly disclosed. However, typical doses for its included ingredients, based on general literature, are: Creatine at 3–5 grams per day, Beta-alanine at 2–5 grams per day, Arginine/AAKG at 3–6 grams pre-workout, and BCAAs at 5–10 grams pre or post-workout. Dark Rage is intended to be taken pre-workout to maximize acute pump and performance effects during exercise. There are no specific cofactors or absorption enhancers noted for this product. Given the proprietary nature of the blend, users should adhere strictly to the manufacturer's recommended serving size on the product label, as the precise amounts of each ingredient are not transparent, making it difficult to assess individual ingredient dosages.

FAQs

Is Dark Rage safe?

Without independent clinical trials on the proprietary blend, the overall safety of Dark Rage cannot be fully confirmed. Individual ingredients are generally safe at recommended doses, but the novel EPO-stimulating claim lacks scientific verification.

Does Dark Rage really increase EPO?

There is no peer-reviewed evidence to support the claim that the proprietary complex in Dark Rage effectively stimulates endogenous EPO production in humans at safe doses. This claim remains unproven.

How soon do effects appear?

The acute effects on muscle pumps and exercise performance are expected to appear shortly after consumption, typically during the workout session itself, consistent with other pre-workout supplements.

Is Dark Rage better than standard NO boosters?

Theoretically, the addition of EPO stimulation could enhance pumps beyond what traditional nitric oxide boosters alone provide. However, this theoretical advantage is currently unproven in clinical studies.

Research Sources

  • https://strefamocy.pl/en/pre-workout-stacks/1115-mhp-dark-rage-894-grams.html – This source is a product page for MHP Dark Rage, providing marketing claims and ingredient lists. It highlights the product's focus on muscle pumps, performance, and endurance through a proprietary blend, including claims of EPO stimulation and nitric oxide pathways. It serves as a primary source for understanding the manufacturer's stated benefits and composition.
  • https://www.samedaysupplements.com/dark-rage-pre-workout-by-mhp-grape-2lb.html – Another product listing, this source reiterates the marketing claims for Dark Rage, emphasizing its role as a pre-workout supplement for enhanced pumps, power, and endurance. It confirms the inclusion of ingredients like creatine, beta-alanine, and arginine, and the proprietary nature of the EPO-stimulating complex. This helps corroborate the product's intended use and key features.
  • https://www.priceplow.com/mhp/dark-rage – This review and product information page discusses Dark Rage's formulation and marketing. It details the proprietary blend and its claimed mechanisms, including the unique EPO-stimulating component. The source provides a critical perspective on the lack of independent research supporting the EPO claims, while acknowledging the presence of established ergogenic aids.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC3314449/ – This is a peer-reviewed article from PubMed Central discussing the effects of erythropoietin (EPO) on exercise performance. It confirms that EPO can increase red blood cell mass and endurance capacity in clinical and doping contexts. However, it implicitly suggests that no safe, legal oral supplements have been demonstrated to significantly stimulate endogenous EPO production in healthy athletes, providing context for the skepticism surrounding Dark Rage's EPO claims.

Recommended Articles

Top Fertility Supplements for Women in 2025

Top Fertility Supplements for Women in 2025

By 2025, new FDA-approved fertility supplements, emphasizing organic ingredients, have shown significant effectiveness in aiding conception for women in their 30s.

Barcode-Scanner Apps & Supplements: A Reality Check

Barcode-Scanner Apps & Supplements: A Reality Check

Barcode-scanner supplement apps vary in accuracy, especially with proprietary blends, but advancements are improving their reliability.

Legal Pre-Workout Supplements for Athletes

Legal Pre-Workout Supplements for Athletes

Legal pre-workout supplements like those with caffeine, beta-alanine, and creatine can safely enhance athletic performance without failing doping tests.

Top Testosterone Boosters for Cyclists: A Buyer's Guide

Top Testosterone Boosters for Cyclists: A Buyer's Guide

For cyclists, choosing testosterone boosters involves finding scientifically-backed, third-party tested products, with top picks including brands like TestoGen and Prime Male.