defatted wheat germ
Also known as: Defatted wheat germ, Wheat germ without oil, Triticum aestivum (wheat) germ, Defatted Wheat Germ
Overview
Defatted wheat germ is the oil-free portion of wheat germ, derived from *Triticum aestivum* (wheat). It is a byproduct of wheat oil extraction and is rich in nutrients and bioactive compounds, including polyamines and phenols. It is used as a dietary supplement for its antioxidant properties and potential health benefits, such as improving metabolic markers and intestinal health. Defatted wheat germ is high in protein, fiber, and antioxidants, while being low in fat. Research on defatted wheat germ is moderately mature, with some clinical trials and in vitro studies available, though the quality of available evidence is variable, and more robust evidence is needed for specific health claims. It is generally consumed as a nutritional supplement or added to foods.
Benefits
Defatted wheat germ offers several potential health benefits, primarily related to its antioxidant properties and positive effects on gastrointestinal health. Studies suggest that it can enhance intestinal antioxidant capacity and reduce oxidative stress markers. Research also indicates that it may improve gut microbiota diversity and reduce gastrointestinal discomfort. While some studies suggest potential benefits for metabolic markers like cholesterol and glucose, the evidence is mixed and requires further investigation. These benefits are generally aimed at healthy individuals or those seeking antioxidant support. More research is needed to determine specific effect sizes and the time course of these benefits.
How it works
Defatted wheat germ primarily exerts its effects through antioxidant activity, scavenging reactive oxygen species (ROS) and reducing oxidative stress. This antioxidant action may influence gut health and metabolic pathways. While specific molecular targets are not definitively identified, it likely interacts with various antioxidant pathways within the body. Its effects are primarily observed in the gastrointestinal system and antioxidant defense mechanisms. Limited data is available regarding its absorption and bioavailability, which may vary based on the preparation and individual factors.
Side effects
Defatted wheat germ is generally considered safe when consumed in moderation. Common side effects are not well-documented, but some individuals may experience gastrointestinal upset. Uncommon and rare side effects are not reported in the available literature. No significant drug interactions have been reported. There are no specific contraindications, but pregnant or breastfeeding women should consult healthcare providers before use. Overall, it is important to consume defatted wheat germ within normal dietary limits to minimize potential adverse effects.
Dosage
There is no established minimum effective dose for defatted wheat germ. Typically, it is used in amounts similar to whole wheat germ, such as 6 grams per day. Optimal dosage ranges are not well-defined and may vary based on specific health goals. There is no established maximum safe dose, but it is generally considered safe within normal dietary limits. No specific timing recommendations exist for its consumption. It is often used as a dietary supplement or added to foods like bread. Bioavailability may be influenced by the food matrix and individual digestive health. No specific cofactors are required for its utilization.
FAQs
Is defatted wheat germ safe to consume?
Defatted wheat germ is generally safe, but consult a healthcare provider if you have concerns or underlying health conditions.
When is the best time to take defatted wheat germ?
There is no specific timing recommended; it can be consumed with meals as part of your daily diet.
What are the expected benefits of consuming defatted wheat germ?
It may improve antioxidant status and gut health; however, individual results can vary. It is not a substitute for medical treatment.
Can defatted wheat germ replace medical treatment?
No, it is not a substitute for medical treatment. Consult a healthcare provider for specific health concerns and medical advice.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7256174/ – This systematic review and meta-analysis examined the effects of wheat germ on metabolic markers. The findings showed mixed results, with no significant impact on total cholesterol levels, indicating that further research is needed to clarify its effects on metabolic health.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3179707/ – This clinical trial assessed the effects of wheat germ on blood cholesterol and triglycerides in healthy individuals. The study focused on gastrointestinal function and insulin resistance, aiming to provide insights into the potential metabolic benefits of wheat germ consumption.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5129044/ – Research on wheat germ diets in animal models demonstrated enhanced intestinal antioxidant capacity and improved gut health. These findings suggest that wheat germ may have beneficial effects on the gut microbiome and antioxidant defense mechanisms, warranting further investigation in human studies.
- https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1435454/full – This study investigates the impact of modified wheat germ on intestinal health and microbial composition. The research highlights the potential of wheat germ to modulate gut microbiota and improve overall intestinal well-being, suggesting its role as a functional food ingredient.
- https://www.scirp.org/journal/paperinformation?paperid=54019 – This paper explores the nutritional and medicinal value of wheat germ, emphasizing its rich content of bioactive compounds. The review discusses the potential health benefits of wheat germ, including its antioxidant and anti-inflammatory properties, and its role in promoting overall health and preventing chronic diseases.
Supplements Containing defatted wheat germ

Congaplex
SP Standard Process

Gastrex
SP Standard Process

Allerplex
SP Standard Process

Neuroplex
SP Standard Process

Ligaplex II
SP Standard Process

Livaplex
SP Standard Process

Cataplex B
SP Standard Process

Ligaplex II
SP Standard Process

Trace Minerals-B12
SP Standard Process

Calcifood Powder
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Catalyn Chewable
SP Standard Process

Ferrofood
SP Standard Process