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Dibasic Acid

Also known as: Oxalic Acid, Malonic Acid, Dibasic Acid

Overview

Dibasic acids are organic compounds characterized by their ability to donate two protons (H+ ions). This classification includes various acids such as oxalic acid (C2H2O4) and malonic acid (C3H4O4). They are primarily sourced from nature or synthesized for diverse industrial applications, including use as chelating agents and in cleaning products. While dibasic acids, particularly oxalic acid, are found in certain foods like spinach and rhubarb, their consumption as dietary supplements is not common. Most research surrounding dibasic acids focuses on industrial applications rather than health benefits, indicating a need for further investigation in the dietary context.

Benefits

Currently, there is no substantial evidence supporting the dietary use of dibasic acids for health benefits. Although specific dibasic acids may possess unique properties, such as chelation of metals, the evidence supporting their efficacy in supplement form is lacking, suggesting that any potential benefits remain unestablished. Rigorous clinical trials would be necessary to ascertain their pharmacological effects on human health.

How it works

Dibasic acids may interact with biological systems primarily through chelation, which involves binding metal ions, potentially affecting metal bioavailability and pH levels. However, empirical research defining their mechanisms of action in humans is limited and they are known for their corrosive properties. Thus, their practical application in dietary contexts is highly questionable, and specific biological pathways have not been elucidated adequately.

Side effects

Dibasic acids are generally regarded as unsafe for dietary consumption due to their corrosive nature. Common side effects of ingestion include severe gastrointestinal irritation resulting from their acidic properties. More rarely, systemic toxicity may occur with substantial exposure, potentially leading to organ damage. There is insufficient research on drug interactions, and due to their corrosive nature, they should be avoided by all populations, particularly in supplement use.

Dosage

No established dosing guidelines exist for dibasic acids as dietary supplements due to significant safety concerns highlighted by their potential for harm if ingested. Furthermore, precise dosage for therapeutic purposes remains undefined, and any form of administration poses considerable risks.

FAQs

Can dibasic acids be taken as supplements?

No, dibasic acids are not intended for human consumption and can be harmful if ingested.

What happens if I accidentally ingest dibasic acid?

Ingestion can cause severe gastrointestinal irritation and may lead to corrosive damage.

Are there any health benefits to dibasic acids?

Currently, there are no proven health benefits associated with dibasic acids in dietary contexts.

Research Sources

  • https://www.journalslibrary.nihr.ac.uk/hta/HTA20420 – The study evaluates various health technologies but does not specifically investigate dibasic acids in dietary use.
  • https://pubmed.ncbi.nlm.nih.gov/31505677/ – This research article explores the properties of organic acids, yet it does not provide evidence for dibasic acids as dietary supplements.
  • https://pubmed.ncbi.nlm.nih.gov/29508691/ – The study focuses on chemical properties and applications of acids, lacking any focus on health benefits.
  • https://www.science.gov/topicpages/f/food+analysis – This resource discusses food analysis techniques without providing relevant data on dibasic acids.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC11699594/ – The literature review provides insights into acid applications, further emphasizing the gap in research on dibasic acids as health supplements.