Digestive Reset Blend Proprietary Blend
Also known as: Digestive enzyme blends, Multi-enzyme supplements, Herbal digestive aids, Digestive Reset Blend Proprietary Blend
Overview
Digestive Reset Blend proprietary blends combine digestive enzymes derived from microbial, plant, or animal sources with herbal extracts traditionally used to support digestion. Enzymes like proteases, amylases, lipases, and lactase help break down proteins, carbohydrates, fats, and lactose, respectively. Herbs such as ginger, fennel, and peppermint have carminative and motility-enhancing properties. These blends are used to improve digestion, reduce symptoms such as bloating, gas, and abdominal distension, and support gut health. Multi-enzyme formulations target various macronutrients, while herbal components may soothe the gastrointestinal tract and reduce discomfort. Research maturity is moderate; individual enzymes and herbs are well studied, but proprietary blends vary and require specific clinical validation. Evidence includes randomized controlled trials (RCTs) and systematic reviews on individual enzymes and herbs; fewer high-quality studies exist on specific proprietary blends.
Benefits
A recent RCT with a multi-digestive enzyme and herbal blend (including proteases, lactase, lipase, amylases, cellulases, ginger root, fennel seed, peppermint leaf) demonstrated a statistically significant reduction in post-meal abdominal distension at 30 minutes (p=0.04) and 90 minutes (p=0.007) compared to placebo in healthy subjects. About 80% of participants reported less distension, with trends toward reduced bloating and indigestion symptoms. Participants reported subjective improvements in digestion and preference for the supplement over placebo, with no adverse effects noted. Evidence primarily comes from healthy adults, suggesting potential benefits for individuals with functional gastrointestinal symptoms such as bloating or mild indigestion. The standardized mean differences for abdominal distension were statistically significant; however, symptom severity improvements showed trends rather than strong significance. Benefits were observed acutely post-meal (within 90 minutes), suggesting immediate digestive support.
How it works
Digestive enzymes catalyze the breakdown of macronutrients into absorbable units, facilitating nutrient absorption and reducing substrate for gas-producing fermentation. Herbal components may modulate gastrointestinal motility, reduce inflammation, and exert carminative effects. It acts primarily on the gastrointestinal tract, improving enzymatic digestion and potentially enhancing gut barrier function indirectly. Enzymes target proteins (proteases), carbohydrates (amylases, lactase), fats (lipases), and fibers (cellulases). Herbs may influence smooth muscle and neural pathways in the gut. Enzymes act locally in the gut lumen; herbal constituents may be absorbed systemically or act locally.
Side effects
The Digestive Reset Blend is generally safe with no reported adverse events in clinical studies of similar blends. Potential interactions with anticoagulants or antiplatelet drugs (e.g., ginger) warrant caution. Contraindications include known allergies to any component, and caution is advised in pregnancy or lactation due to herbal ingredients. Limited data exists for children, pregnant women, or individuals with severe gastrointestinal disease. It's important to note that while no common side effects were reported in the cited RCT, individual reactions can vary. Always review the full ingredient list for potential allergens or sensitivities.
Dosage
Typically, 1-2 capsules or tablets are taken with meals. The minimum effective dose is not standardized; clinical studies used commercially available proprietary blends at doses consistent with product labeling. The maximum safe dose is not well defined, so it's important to follow manufacturer recommendations. It should be taken with or immediately before meals to maximize digestive support. Capsules or tablets are designed to release enzymes in the stomach or small intestine. Enzymes act locally, and acid-resistant formulations may improve efficacy. Some enzymes require cofactors like calcium or zinc, but proprietary blends usually include stabilized forms.
FAQs
Does the blend help with bloating?
Yes, evidence shows a significant reduction in post-meal abdominal distension and trends toward less bloating.
Is it safe to take daily?
Clinical studies report no adverse effects with typical dosing.
When should I take it?
Ideally, take it with meals to aid digestion.
Will it replace digestive enzymes my body produces?
No, it supplements endogenous enzymes temporarily.
Are herbal ingredients effective?
Herbs like ginger and peppermint have documented digestive benefits and contribute to symptom relief.
Research Sources
- https://www.dovepress.com/a-multi-digestive-enzyme-and-herbal-dietary-supplement-reduces-bloatin-peer-reviewed-fulltext-article-NDS – This randomized, placebo-controlled trial with healthy adults (n≥30) assessed the acute post-meal effects of a multi-digestive enzyme and herbal blend. The study found a significant reduction in abdominal distension at 30 and 90 minutes post-meal (p=0.04 and p=0.007), with 80% of participants reporting less distension and no adverse events.
- https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1143548/full – This systematic review on probiotics and gut barrier function included 5 RCTs with 385 subjects, showing significant improvement in serum zonulin (SMD -1.58, p=0.0007). While not directly on digestive enzyme blends, this review supports the role of probiotics in improving gut barrier and reducing inflammation, which may complement digestive blends in gut health.
- https://onlinelibrary.wiley.com/doi/abs/10.1111/jhn.13090 – This systematic review on probiotics in IBS and digestive health suggests that probiotics can benefit IBS and other functional gut disorders. This indicates that multi-component blends including enzymes and herbs may have synergistic effects in improving digestive health.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5900870/ – This article discusses the role of digestive enzymes in human nutrition. It highlights how supplemental enzymes can aid in the digestion of macronutrients and alleviate digestive discomfort, particularly in individuals with enzyme deficiencies or digestive disorders.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10744015/ – This review explores the potential benefits of herbal remedies for digestive health. It examines the mechanisms of action and clinical evidence supporting the use of various herbs, such as ginger and peppermint, in managing digestive symptoms like bloating, gas, and indigestion.
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