Doterra On Guard Protective Blend
Also known as: doTERRA On Guard, On Guard Protective Blend, protective essential oil blend
Overview
doTERRA On Guard Protective Blend is a proprietary blend of essential oils including cinnamon bark (*Cinnamomum verum*), lemon peel (*Citrus limon*), eucalyptus (*Eucalyptus globulus*), rosemary (*Rosmarinus officinalis*), and clove bud (*Syzygium aromaticum*). It is marketed for its potential immune-supporting, antioxidant, and cleansing properties. The blend contains volatile organic compounds such as cinnamaldehyde, eugenol, limonene, 1,8-cineole, and α-pinene. While it's promoted for various health benefits, the available research is primarily preclinical or in vitro, with limited high-quality human studies. It is available for aromatic, topical, and internal use, though internal use should be approached with caution. The blend is generally considered safe for topical and aromatic use in adults, but safety for ingestion is less established. More clinical research is needed to validate its purported benefits and ensure its safety.
Benefits
The primary evidence for On Guard's benefits comes from in vitro studies. One study showed a significant reduction in influenza virus infectivity in MDCK cells, with minimal viral protein expression and reduced viral particle release. However, this is an in vitro finding and may not translate to clinical benefits in humans. A manufacturer-funded study reported reduced inflammatory markers in human cells, but this has not been confirmed in clinical trials. Individual components like cinnamon, clove, and eucalyptus have demonstrated antimicrobial and immune-enhancing effects in laboratory studies, but the combined effect of the blend requires further investigation. Currently, there is no robust evidence to support specific benefits in particular populations.
How it works
The mechanism of action for On Guard Protective Blend is not fully elucidated, but in vitro studies suggest it may inhibit viral protein synthesis post-transcription. Specifically, research indicates that the blend can attenuate influenza virus infectivity by interfering with viral protein production in infected cells. Additionally, the blend may modulate inflammatory pathways and exhibit antioxidant activity due to the properties of its individual components. The essential oils are thought to interact with the immune and inflammatory systems, potentially influencing host cell signaling. However, the exact molecular targets and systemic bioavailability of the blend's components remain poorly characterized.
Side effects
On Guard Protective Blend is generally considered safe for topical and aromatic use in most adults. Common side effects include skin irritation from topical application and mild gastrointestinal upset if ingested. Uncommon side effects include allergic reactions and contact dermatitis. Rare side effects may include severe allergic reactions and respiratory irritation. Due to the presence of clove and cinnamon, there is a potential for interactions with anticoagulants, although this is not well-documented. The blend is contraindicated for individuals with allergies to any of its components. Caution is advised during pregnancy, in children, and for individuals with sensitive skin. It is not recommended for use in infants or young children without medical supervision.
Dosage
There is no established minimum effective dose, optimal dosage range, or maximum safe dose for On Guard Protective Blend in humans. Manufacturer recommendations vary depending on the application method (diffusion, topical, or ingestion). For diffusion and topical use, follow the manufacturer's instructions. Ingestion should be approached with caution due to the potency of essential oils and potential toxicity at high doses. There are no established timing considerations or required cofactors. Absorption varies depending on the route of administration. Due to the lack of clinical data, it is crucial to adhere to conservative usage guidelines and avoid excessive exposure.
FAQs
Is On Guard Protective Blend safe for children and pregnant women?
Essential oils are highly concentrated and should be used with caution, especially in children and pregnant women. Consult with a healthcare professional before use in these populations.
How should I use On Guard Protective Blend for immune support?
There are no evidence-based guidelines for using On Guard for immune support. Follow manufacturer instructions with caution, recognizing that clinical benefits are unproven.
Can On Guard Protective Blend replace vaccines or antiviral medications?
No, On Guard is not a substitute for vaccines or proven antiviral medications. Evidence for immune support in humans is limited, and it should not be relied upon as a primary treatment.
What are the potential side effects of using On Guard Protective Blend?
Potential side effects include skin irritation (topical), mild gastrointestinal upset (ingestion), allergic reactions, and, rarely, severe allergic or respiratory reactions. Discontinue use if adverse effects occur.
Research Sources
- https://www.doterra.com/US/en/blog/science-research-news-doterra-on-guard-study – This doTERRA blog post summarizes an in vitro study on On Guard's effects on influenza virus. The study found that On Guard significantly attenuated influenza virus infectivity by inhibiting viral protein synthesis, without affecting viral binding or internalization. This suggests a potential antiviral mechanism, but it's important to note that this is an in vitro model and not human data.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC2994788/ – This article discusses the antiviral properties of essential oils. While it doesn't focus specifically on On Guard, it provides context for the potential mechanisms by which essential oils, including those in the blend, may exert antiviral effects. It highlights the need for further research to validate these findings in clinical settings.
- https://www.doterra.com/US/en/p/on-guard-oil – This is the official doTERRA product page for On Guard oil. It provides information on the blend's ingredients and purported benefits, as well as usage instructions. However, it's important to consider that this is a commercial source and may present a biased view of the product's efficacy.
- https://www.doterra.com/US/en/blog/spotlight-doterra-on-guard-protective-blend – This doTERRA blog post highlights the On Guard Protective Blend, focusing on its potential benefits and uses. It emphasizes the blend's purported immune-supporting and cleansing properties. As a promotional piece, it should be read with caution, and its claims should be verified with independent research.
- https://www.healthline.com/health/cold-flu/on-guard-doterra – This Healthline article discusses doTERRA's On Guard oil in the context of cold and flu remedies. It provides an overview of the blend's ingredients and potential benefits, while also noting the limited scientific evidence supporting its use. The article advises caution and suggests consulting with a healthcare professional before using On Guard for medicinal purposes.
Supplements Containing Doterra On Guard Protective Blend
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