Eleutherococcus Senticosus Root Standardized Extract
Also known as: Eleutherococcus senticosus, Siberian Ginseng, Eleuthero
Overview
Eleutherococcus senticosus, commonly known as Siberian Ginseng or Eleuthero, is a plant native to Northeast Asia renowned for its adaptogenic properties. The root and bark of the plant are primarily used to enhance the body's resilience to stress, improve physical and mental performance, and promote overall well-being. As an adaptogen, it is believed to modulate the body's stress response, helping it adapt to various stressors. It is available in various forms, including capsules, tablets, liquid extracts, and powders. While research suggests potential benefits such as improved endurance and reduced fatigue, more rigorous clinical trials and systematic reviews are needed to fully validate these effects. Eleuthero is distinct from true ginseng (Panax species) and should not be confused with it.
Benefits
Eleutherococcus senticosus may offer several benefits, particularly for individuals under stress or athletes seeking to improve physical performance. Studies suggest it can enhance endurance and reduce fatigue, although specific quantified outcomes are limited. It may also possess anti-inflammatory and immune-modulating effects, potentially benefiting the immune system. The adaptogenic properties of Eleuthero may help the body better manage stress, improving overall well-being. However, the evidence is not strong enough to provide precise effect sizes, and benefits are generally observed after prolonged use. More high-quality research is needed to confirm these benefits and determine optimal usage guidelines.
How it works
Eleutherococcus senticosus is believed to exert its adaptogenic effects by modulating stress response pathways within the body. It interacts with the immune and nervous systems, enhancing the body's ability to adapt to stressors. While the exact molecular targets are not well-defined, it likely affects various signaling pathways involved in stress response. This modulation helps to improve resilience and reduce the negative impacts of stress on the body. Further research is needed to fully elucidate the precise mechanisms of action and the bioavailability of its active compounds.
Side effects
Eleutherococcus senticosus is generally considered safe when used appropriately, but some side effects have been reported. Common side effects (occurring in >5% of users) include gastrointestinal issues such as nausea or diarrhea. Uncommon side effects (1-5%) may include headaches and dizziness. Rare side effects (<1%) can include allergic reactions. It may interact with blood thinners and diabetes medications, so caution is advised for individuals taking these drugs. Eleutherococcus senticosus is contraindicated in pregnancy and breastfeeding due to insufficient safety data. Caution is also advised in individuals with autoimmune diseases. It is important to consult with a healthcare provider before use, especially if you have underlying health conditions or are taking other medications.
Dosage
The typical recommended dosage of Eleutherococcus senticosus is 2-3 grams of the root per day, or equivalent aqueous-alcoholic extracts. Liquid extracts (1:1, ethanol 40% v/v) can be used at 20-40 drops, 2-3 times daily. It is best taken in the morning to enhance daytime performance. The maximum safe dose is not well-defined, so it is important to use as directed. Bioavailability may be influenced by the extraction method. It is important to consult with a healthcare provider to determine the appropriate dosage for individual needs.
FAQs
What are the expected results from taking Eleutherococcus senticosus?
Common benefits include improved endurance and reduced fatigue. It is important to take it consistently over a period to observe these benefits.
Is Eleutherococcus senticosus safe?
While generally safe, it should be used with caution in certain populations, such as pregnant or breastfeeding women, and individuals with autoimmune diseases. Consult a healthcare provider before use.
How should I take Eleutherococcus senticosus?
It is best taken consistently over a period to observe benefits. Consult with a healthcare provider before starting any supplement regimen, especially if you have underlying health conditions.
Is Eleutherococcus senticosus the same as true ginseng?
No, it is not a true ginseng and should not be confused with *Panax ginseng*. They have different chemical compositions and effects.
Research Sources
- https://www.mdpi.com/1660-4601/20/7/5298 – This study explores the adaptogenic effects of *Eleutherococcus senticosus*, finding that it enhances the body's ability to adapt to stressors. While the study highlights the potential benefits, it notes that specific outcomes were not quantified, indicating a need for more precise measurements in future research.
- https://www.mdpi.com/1420-3049/29/4/866 – This comparative study on root and bark extracts of *Eleutherococcus senticosus* demonstrates potential anti-inflammatory effects by modulating macrophage functions. The findings suggest that the plant's extracts could play a role in reducing inflammation through specific interactions with immune cells.
- https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-eleutherococcus-senticosus-rupr-et-maxim-maxim-radix_en.pdf – This final assessment report by the European Medicines Agency provides a comprehensive overview of *Eleutherococcus senticosus*, evaluating its traditional uses and safety profile. The report serves as a regulatory document, summarizing the available evidence and outlining guidelines for its use as a herbal medicine.
- https://www.droracle.ai/articles/133338/eluethero-extract-vs-ashwagandha-vs-rhodiola – This article compares Eleuthero extract with other adaptogens like Ashwagandha and Rhodiola, highlighting their respective benefits and uses. It provides a general overview of how each adaptogen works and the specific conditions they are best suited for, offering a comparative perspective for consumers.
- https://pubmed.ncbi.nlm.nih.gov/32065954/ – This study investigates the effects of *Eleutherococcus senticosus* on human health, focusing on its potential to improve physical and mental performance. The research contributes to the growing body of evidence supporting the adaptogenic properties of the plant and its role in enhancing overall well-being.