Energizing Fruit Proprietary Blend
Also known as: Energizing Fruit Proprietary Blend, Botanical Dietary Supplement Blend, Nutraceutical Blend, LN18178, Tesnor®, Fruit-Derived Proprietary Blend
Overview
A Fruit-Derived Proprietary Blend is a non-specific term referring to a mixture of fruit-derived extracts or powders, typically designed to provide energy, vitality, or other health benefits. The exact composition varies by product, but commonly includes fruits rich in antioxidants, polyphenols, and other bioactive compounds such as pomegranate (Punica granatum) and cocoa (Theobroma cacao). These blends are classified as botanical dietary supplement blends or nutraceuticals. They are generally formulated to support energy metabolism, anti-aging processes, hormonal balance, and muscle strength. While individual fruit extracts have been extensively studied, the research maturity for specific proprietary blends can vary, with some having undergone randomized controlled trials (RCTs) demonstrating efficacy, though often with small sample sizes or short durations.
Benefits
A specific proprietary blend (LN18178/Tesnor®) containing standardized pomegranate fruit rind and cocoa seed extracts has shown significant benefits in a randomized, double-blind, placebo-controlled trial. This blend improved aging males’ symptoms, muscular strength, and serum testosterone levels over 56 days (p<0.05), indicating efficacy for hormonal and strength support in this population. General systematic reviews on fruit consumption suggest that increased intake of whole fruits can modestly reduce energy intake and body weight, implying a potential for fruit-based blends to aid energy metabolism and weight management. These effects on energy intake and adiposity are moderate but consistent, particularly when fruit is consumed pre-meal or as a substitute for energy-dense foods. Therefore, population-specific benefits include aging males for hormonal support and overweight individuals for weight management.
How it works
The mechanism of action for fruit-derived proprietary blends involves the synergistic effects of their bioactive compounds, such as polyphenols, flavonoids, theobromine, and punicalagins. These compounds act as potent antioxidants and can modulate various biological pathways. For instance, cocoa seed extract contains methylxanthines like theobromine and caffeine, which stimulate the central nervous system, potentially increasing alertness and energy. Pomegranate rind polyphenols exert anti-inflammatory and antioxidant effects, which may support muscle function and contribute to hormonal balance, including testosterone synthesis. The overall blend influences energy metabolism and interacts with body systems to promote vitality and well-being. Absorption and bioavailability of these compounds depend on the specific extract standardization and formulation, but are generally moderate for polyphenols.
Side effects
The LN18178 blend, a specific fruit-derived proprietary blend, was well tolerated in a 56-day randomized controlled trial, with no significant adverse events reported. Generally, common side effects of fruit extracts are rare and, if they occur, are typically mild gastrointestinal discomfort. There have been no significant drug interactions or contraindications reported for the studied blend. However, it is important to note that sufficient safety data is lacking for special populations, such as pregnant women and children, and therefore, conclusions regarding their safety in these groups cannot be made. As with any supplement, individual sensitivities may vary, and it is advisable to consult a healthcare professional before use, especially if you have pre-existing medical conditions or are taking other medications.
Dosage
Optimal dosage ranges for fruit-derived proprietary blends are not well established due to their variable compositions. However, the LN18178 study utilized a dose consistent with standardized extract amounts, though specific product details are required for precise dosing. Generally, typical fruit extract doses range from 100 mg to 500 mg of standardized polyphenols daily. The timing of consumption may influence efficacy; for example, consuming fruit-based blends pre-meal has been shown to help control energy intake. Absorption of the active compounds can sometimes be enhanced with food or through specific formulation technologies. It is crucial to follow the dosage instructions provided by the manufacturer of a specific proprietary blend, as formulations and concentrations can differ significantly.
FAQs
Is the blend safe?
Based on randomized controlled trial data for specific blends like LN18178, it is generally considered safe and well tolerated with no significant adverse events reported.
How quickly do benefits appear?
In the cited RCT, hormonal and strength benefits were observed within 56 days of consistent use of the LN18178 blend.
Does it aid weight loss?
Indirectly, by potentially increasing fruit intake and reducing overall energy intake, it may support modest weight management efforts, especially when consumed pre-meal.
Is it stimulatory like caffeine?
Some blends containing cocoa components may provide mild stimulation due to methylxanthines, but the extent of this effect depends on the specific blend's composition and concentration.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9346391/ – This high-quality randomized, double-blind, placebo-controlled trial investigated the effects of the LN18178/Tesnor® blend in 120 aging males over 56 days. It found significant improvements in aging male symptoms, muscular strength, and serum testosterone levels, demonstrating the blend's efficacy for hormonal and strength benefits in this population.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4158137/ – This systematic review and meta-analysis examined multiple RCTs on increasing fruit and vegetable intake. It concluded that increased fruit intake modestly reduces body weight and energy intake, providing indirect evidence that fruit-based blends could support weight management by influencing energy consumption.
- https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2019.00066/full – This systematic review focused on RCTs concerning whole fruit consumption and its impact on energy intake. It found that whole fruit consumption, especially when consumed pre-meal, consistently reduces subsequent energy intake, suggesting a mechanism by which fruit-derived blends might contribute to energy control and weight management.
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