ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Epazote

Also known as: Epazote, Mexican Tea, Wormseed, Chenopodium ambrosioides, Dysphania ambrosioides

Overview

Epazote is a pungent leafy herb native to Central and South America, commonly used in Mexican cuisine, particularly with beans and soups. It is renowned for its anti-flatulence properties and traditional use as a digestive aid. The herb contains active compounds like ascaridole, which contribute to its properties. Although it is traditionally utilized for digestive discomfort, available research mainly focuses on its ethnobotanical uses and chemical composition, revealing limited clinical evidence to support its efficacy as a dietary supplement.

Benefits

Epazote's health benefits are largely anecdotal with limited scientific backing. Traditionally, it is thought to aid digestion and reduce flatulence, especially when used in cooked dishes, but there are no high-quality clinical studies, such as randomized controlled trials or meta-analyses, to quantify these effects or confirm its efficacy in treating digestive issues. Its ethnobotanical use suggests potential benefits, yet without rigorous testing, these claims remain speculative.

How it works

The active compounds in epazote, particularly ascaridole and various volatile oils, are believed to contribute to its anti-parasitic and digestive effects. Ascaridole's interaction with gastrointestinal physiology is not thoroughly studied, with unclear mechanisms of how these compounds affect digestive and parasitic processes within the body. Further research is required to elucidate these biological pathways.

Side effects

Epazote can be toxic in large doses due to the presence of ascaridole, leading to potential neurological symptoms. Although specific common side effects are not well-documented, there exists a risk of allergic reactions or interactions with certain medications. Pregnant women should avoid taking epazote, as it poses potential teratogenic risks. The lack of comprehensive data on morbidity from side effects underscores the need for caution and further research.

Dosage

Current research does not provide established dosing guidelines for epazote as a supplement. Traditionally, the leaves are cooked in dishes to mitigate bitterness and potential toxicity. Given the uncertainty around optimal dosage for therapeutic effects and safety, users should approach this herb carefully, particularly regarding high doses, which may lead to adverse effects.

FAQs

What are the usage concerns related to epazote?

Epazote is traditionally used in cooking rather than as a dietary supplement, and scientific evidence supporting its supplement use is limited.

Is epazote safe for everyone?

High doses can be toxic, and it is not recommended for pregnant women due to potential teratogenic effects.

How should epazote be consumed?

It is typically used in cooked dishes, as cooking can reduce its bitterness and potential toxicity.

Research Sources

  • https://www.elsevier.es/en-revista-annals-hepatology-16-avance-resumen-anti-hepatitis-b-virus-activity-food-S1665268122001089 – This article reviews anti-HBV activities of various foods but lacks a direct focus on epazote’s efficacy or safety.
  • https://downloads.regulations.gov/EPA-HQ-OPP-2024-0562-0003/content.pdf – This document discusses regulatory perspectives on herbal supplements, including short mentions of varying herbs, although specifics on epazote were limited.
  • https://www.adaptiveseeds.com/product/herbs/epazote-oaxaca-red-organic/ – This product information webpage describes the traditional uses of epazote, highlighting its culinary applications and traditional medicinal properties.
  • https://escholarship.org/content/qt7nq3x9c7/qt7nq3x9c7_noSplash_b1b6b998a2ecc163bd64c21a7ced3347.pdf?t=qipbww – An academic resource providing insights on various herbs' applications, with only brief references to epazote’s use in traditional medicine.
  • https://www.researchgate.net/publication/388379954_Efficacy_of_fish_oil_supplementation_on_metabolic_dysfunction-associated_steatotic_liver_disease_a_meta-analysis – While focusing on fish oil supplementation, this meta-analysis exemplifies the need for similar rigorous studies on other herbal supplements like epazote.

Supplements Containing Epazote

Parasite Cleanse 1000 mg by Remedys Nutrition
40

Parasite Cleanse 1000 mg

Remedys Nutrition

Score: 40/100
Living Defense by InfoWars Life
48

Living Defense

InfoWars Life

Score: 48/100
Epazote Alcohol Free by Hawaii Pharm
45

Epazote Alcohol Free

Hawaii Pharm

Score: 45/100
Epazote by Hawaii Pharm
45

Epazote

Hawaii Pharm

Score: 45/100
Paraherbs by MH Michael's Health Naturopathic Programs
48

Paraherbs

MH Michael's Health Naturopathic Programs

Score: 48/100
Paraherbs by MH Michael's Health Naturopathic Programs
48

Paraherbs

MH Michael's Health Naturopathic Programs

Score: 48/100
Black Walnut Hull Complex by MH Michael's Health Naturopathic Programs
50

Black Walnut Hull Complex

MH Michael's Health Naturopathic Programs

Score: 50/100