ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Euryale Ferox

Also known as: Fox nut, Makhana, Gorgon nut, *Euryale ferox*

Overview

*Euryale ferox*, commonly known as fox nut or Makhana, is a nutrient-rich aquatic plant native to tropical Southeast Asia, particularly India and China. It is widely recognized in traditional medicine for its therapeutic properties, particularly in treating kidney disorders and circulatory issues. This plant is abundant in carbohydrates, proteins, fiber, vitamins, and minerals, which contribute to its function as a health-promoting food. Research indicates potential health benefits, including antioxidant, antidiabetic, antihyperlipidemic, and cardioprotective effects. Despite its popularity, the level of research maturity varies, with limited systematic reviews and meta-analyses available to substantiate its efficacy comprehensively.

Benefits

*Euryale ferox* is noted primarily for its antioxidant and cardioprotective properties, potentially alleviating myocardial ischemic reperfusion injury. Secondary effects include possible antidiabetic and anti-inflammatory benefits, although these require more research for confirmation. Traditionally, it has been used for kidney disorders and improving circulation, suggesting its utility for populations suffering from these conditions. While specific quantitative data is sparse, preliminary findings indicate significant bioactive potential, warranting larger-scale clinical trials for robust validation of its benefits.

How it works

The active constituents of *Euryale ferox*, such as oleic acid and vitamin E, modulate biological pathways including MAPK and regulate TNF pathways. These actions primarily affect cardiovascular and renal health, potentially providing protections against ischemic damage and improving kidney function. Molecular targets involve proteins like PPARA and MAPK1, essential for regulating lipid metabolism and inflammatory responses.

Side effects

While *Euryale ferox* is generally regarded as safe for consumption in food forms, specific safety data for supplement usage is lacking. Adverse effects are not frequently reported, with common, uncommon, or rare side effects remaining largely unknown. Potential interactions with diabetes or cardiovascular medications have been suggested but are still uncertain and merit further investigation. Pregnant or breastfeeding individuals are advised to consult healthcare professionals due to insufficient safety data regarding its use in these populations.

Dosage

Currently, there is no established minimum effective dose or maximum safe limit for *Euryale ferox* as a supplement, leading to variability in suggested dosages based on traditional practices. Often, it is consumed roasted or in powdered form. No particular timing for ingestion has been recommended, and the absorption rates of the constituents remain unclear. Due to this variability and lack of standardized dosing, users are encouraged to follow traditional dosages or consult healthcare providers.

FAQs

How can I incorporate *Euryale ferox* into my diet?

You can add roasted fox nuts to snacks or smoothies, or use the powder in recipes. Consult healthcare providers if you're considering supplements.

Is *Euryale ferox* safe for everyone?

Generally safe as a food, but consult a healthcare provider if you have health conditions or are pregnant/breastfeeding due to limited data.

What are the expected results from using *Euryale ferox*?

Expected results can vary significantly based on individual health status and the form consumed. More research is needed for consensus.

Research Sources

  • https://onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.14409 – This study investigates the therapeutic potential of *Euryale ferox* components, particularly oleic acid and vitamin E, in treating diabetic kidney disease through targeted pathways.
  • https://pubmed.ncbi.nlm.nih.gov/16628469/ – Research highlights the cardioprotective effects of *Euryale ferox* seeds in reducing myocardial ischemic reperfusion injury in animal models, underpinning its traditional medicinal uses.
  • https://medcraveonline.com/APAR/anti-aging-amino-acids-in-euryale-ferox-salisb-a-review.html – This review emphasizes the presence of anti-aging amino acids in *Euryale ferox*, contributing to its health benefits, although clinical data supporting these effects are limited.
  • https://pubmed.ncbi.nlm.nih.gov/36183158/ – A recent study focuses on the composition and health benefits of *Euryale ferox*, highlighting potential applications in modern nutritional science and traditional medicine.
  • https://ouci.dntb.gov.ua/en/works/lDQbReg9/ – This resource provides insights into the application of *Euryale ferox* in pharmacology, discussing potential therapeutic uses and necessitating further research for conclusive applications.