Eurycoma Longifolia Jack Root Extract
Also known as: Tongkat Ali, Long Jack, Eurycoma longifolia
Overview
*Eurycoma longifolia*, commonly known as Tongkat Ali, is a herbal supplement derived from the root of a plant native to Southeast Asia, particularly Malaysia and Indonesia. It has been used traditionally for various medicinal purposes, primarily focused on enhancing male fertility and sexual health. The root contains bioactive compounds, such as quassinoids, canthin-6-one alkaloids, and β-carboline alkaloids, which are believed to contribute to its potential health benefits. Modern applications often concentrate on its role in testosterone enhancement and improved physical performance. Despite its increasing popularity and moderate level of research interest, the quality of available evidence remains variable, necessitating further clinical trials to adequately confirm its efficacy and safety for long-term use.
Benefits
Several studies have highlighted the potential benefits of *Eurycoma longifolia* supplementation. A systematic review and meta-analysis indicated that it significantly increases total testosterone levels in men, with a standardized mean difference (SMD) of 1.352, demonstrating clinical significance. Additionally, there are indications that it may improve sperm parameters and reduce stress, particularly beneficial for hypogonadal men. However, while testosterone enhancements are consistent, evidence regarding additional benefits, such as sperm quality improvement, is limited, warranting cautious interpretation of these findings.
How it works
The mechanisms through which *Eurycoma longifolia* exerts its effects are not completely understood but are believed to involve the enhancement of the hypothalamic-pituitary-gonadal axis's function, which is crucial for testosterone production. Its bioactive compounds, particularly quassinoids, might influence hormonal pathways or alter the stress response, leading to increased testosterone levels. Although the exact molecular targets remain unidentified, these interactions are likely pivotal in modulating testosterone synthesis and overall male reproductive health.
Side effects
Overall, *Eurycoma longifolia* is generally considered safe for short-term use; however, comprehensive safety data are lacking, especially concerning long-term usage. The adverse effects are not well documented, with common and rare side effects remaining unclear due to limited studies. Some potential interactions with medications, such as propranolol and hypoglycemic agents, raise concerns regarding its safety for individuals on such treatments. Caution is also advised in individuals with specific health conditions, including heart and kidney disease. Given the insufficient safety data, it is advisable to avoid this supplement during pregnancy and breastfeeding.
Dosage
For optimal benefits, the recommended dosage of *Eurycoma longifolia* extract typically ranges from 200-300 mg per day. However, established optimal or maximum dosages are not well-defined, and caution is generally advised when exceeding standard recommendations. There are no specific timing guidelines for taking the supplement, and the forms used often include freeze-dried water extracts. Variability in individual absorption rates is another concern, making it essential to adhere to product instructions for use.
FAQs
How long does it take to see results from *Eurycoma longifolia*?
Results may typically be observed within a few weeks to months of consistent supplementation.
Is it safe to use *Eurycoma longifolia* with medications?
Caution is advised as it may interact with medications, particularly propranolol and hypoglycemic agents.
Can women take *Eurycoma longifolia*?
It is generally recommended to avoid use in women, especially during pregnancy and breastfeeding, due to insufficient safety data.
What should I look for when purchasing *Eurycoma longifolia* supplements?
Ensure that the product is from a reputable source to avoid adulteration and to ensure quality.
Is *Eurycoma longifolia* effective for improving athletic performance?
While touted for its ergogenic effects, evidence is inconclusive, and more research is needed.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/36013514/ – This systematic review and meta-analysis analyzed nine studies, focusing on the effect of *Eurycoma longifolia* on testosterone levels, finding a significant increase in total testosterone among men, though it highlighted the need for further research on long-term outcomes.
- https://www.ncbi.nlm.nih.gov/books/NBK609015/ – A meta-analysis of randomized controlled trials examined *Eurycoma longifolia*'s effects on erectile function, suggesting potential benefits in severe cases, while noting a high risk of bias across the included studies.
- https://www.publish.csiro.au/hc/pdf/HC22143 – An open study observed improvements in sperm concentration and morphology among men with idiopathic male infertility, but lacked randomization and control, which limits the quality and applicability of the findings.
- https://www.semanticscholar.org/paper/Eurycoma-longifolia-%28Jack%29-Improves-Serum-Total-in-Leisegang-Finelli/46f0ba1828eb17cd109fdbe88aacbe70b123b8fa – This study reported significant enhancements in serum total testosterone levels among participants, emphasizing the need for further controlled trials to validate its safety and effectiveness.
- https://onlinelibrary.wiley.com/doi/10.1155/2022/4999797 – A review exploring various health claims associated with *Eurycoma longifolia*, evaluating existing clinical trials and highlighting areas where more robust evidence is necessary.