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Evnol

Also known as: EVNol SupraBio, Alpha-tocotrienol, Tocotrienols, Vitamin E family

Overview

EVNol SupraBio is a patented, bioenhanced form of tocotrienols, which are part of the vitamin E family. These compounds are primarily sourced from palm oil and are known for their high bioavailability and antioxidant properties. Tocotrienols differ chemically from tocopherols, another vitamin E component, and they serve significant roles in neuroprotection and cardiovascular health. They're especially noted for their potential to mitigate the risks of stroke and dementia while promoting overall heart health. Research indicates that the absorption of tocotrienols occurs rapidly and accumulates in key organs, such as the brain and heart, enhancing their efficacy. While existing studies primarily focus on neuroprotection and cardiovascular effects, the body of independent research is still developing, necessitating further investigation to thoroughly understand their impacts across various health conditions.

Benefits

EVNol SupraBio has shown several evidence-based benefits. Notably, it may enhance neuroprotection by reducing the progression of white matter lesions, thereby potentially lowering the risk of stroke and dementia. Several studies suggest it can also positively affect cardiovascular health by reducing overall and LDL cholesterol levels in individuals with high cholesterol. Additionally, preliminary studies indicate potential benefits for liver health by improving fatty liver conditions and possibly enhancing hair growth. While elderly populations may see pronounced neuroprotective effects, individuals with cardiovascular challenges may experience favorable lipid profiles. However, specific effect sizes remain poorly documented outside of manufacturer-sponsored studies, which clouds the clinical significance of these findings.

How it works

The mechanism of action of EVNol SupraBio involves modulating critical biological pathways related to neuronal cell survival and apoptosis. It inhibits c-Src kinase activation and up-regulates multidrug resistance-associated protein 1 (MRP1), which are crucial processes in neuroprotection. Furthermore, tocotrienols interact with various body systems, influencing neuronal, cardiovascular, and hepatic functions. Molecular targets include key enzymes such as 12-lipoxygenase and phospholipase A2, orchestrating the antioxidant effects and promoting cellular health across vital organ systems.

Side effects

EVNol SupraBio is generally regarded as safe, with limited long-term safety data available. Common side effects have not been well-documented in independent studies, but gastrointestinal upset is noted as a possible outcome, though infrequent. No specific rare side effects are currently established. Caution is advised with anticoagulant medications due to potential effects on platelet function. Pregnant or breastfeeding women are recommended to consult healthcare providers before use. No known contraindications exist, but individuals with bleeding disorders should approach with caution.

Dosage

The optimal dosage recommended for neuroprotection is 200 mg taken twice daily, based on manufacturer studies. However, the minimum effective dose is not well-established in independent research, and the maximum safe dose remains undefined. Timing for administration is not specified, and EVNol SupraBio does not necessitate dietary fat for effective absorption. It is predominantly available in capsule form. No required cofactors are noted for enhanced absorption.

FAQs

Is EVNol SupraBio safe to use?

Generally, EVNol SupraBio is considered safe, but long-term safety data are limited. It's advisable to consult a healthcare provider, especially if there are pre-existing health conditions.

How long does it take to see results?

Benefits from EVNol SupraBio may become evident within several months of consistent supplementation, though individual results can vary.

Can EVNol SupraBio cure diseases?

No, EVNol SupraBio is not a cure for diseases but may support health and well-being in certain conditions.

Research Sources

https://www.hpcimedia.com/images/PDF/EVNol_Excelvite.pdf – This document outlines the efficacy of EVNol SupraBio in various clinical settings, emphasizing its neuroprotective properties and potential cardiovascular benefits in human populations.
https://www.nutraceuticalbusinessreview.com/clinical-study-on-blood-outcome-and-brain-protection-with-evnol-suprabio-119069 – A clinical study demonstrating the effects of EVNol SupraBio on blood lipid profiles and brain protection, providing insights into its applications for ischemic stroke survivors.
https://www.excelvite.com/tocotrienol-decreases-hba1c-in-t2dm/ – This study discusses the impact of tocotrienols, including EVNol SupraBio, on lowering HbA1c levels in individuals with Type 2 diabetes, suggesting metabolic benefits.
https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0255205 – This research illustrates the effects of EVNol SupraBio on stroke-induced infarct volume using animal models, highlighting its potential neuroprotective effects in pre-clinical studies.
https://pubmed.ncbi.nlm.nih.gov/37321474/ – This PubMed entry summarizes preliminary findings from a study exploring the biochemical effects of tocotrienols, linking them to improvements in lipid metabolism and cellular health.