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Evnolmax

Also known as: EVNolmax, EVNol SupraBio, alpha-tocotrienol, Tocotrienols

Overview

Tocotrienols are a subclass of Vitamin E distinct from tocopherols, known for their potent antioxidant and neuroprotective properties. They are naturally found in various plant oils, including palm oil, rice bran oil, and annatto oil. EVNol SupraBio is a formulated version of tocotrienols that is recognized for its high bioavailability, allowing it to effectively accumulate in vital organs such as the brain, heart, liver, and skin. Over the past two decades, research has increasingly explored tocotrienols for their potential benefits in supporting brain health, cardiovascular function, and acting as antioxidants. Existing evidence includes a mix of pre-clinical studies and clinical trials, though more large-scale trials are needed for thorough validation of its health benefits.

Benefits

Research has spotlighted several evidence-based benefits of EVNol SupraBio. Key findings include: 1) **Brain Health**: A significant reduction in the risk of stroke and dementia was observed in a clinical study with subjects having White Matter Lesions (WMLs). 2) **Cardiovascular Health**: Studies indicate a notable decrease in total cholesterol and LDL-cholesterol levels in hypercholesterolemic subjects over four months. 3) **Neuroprotection**: Pre-clinical models demonstrated reductions in stroke-related infarct volumes by 20-40%, signaling substantial neuroprotective effects. Secondary benefits include evidence of kidney protection in diabetic nephropathy and improved liver function in patients with end-stage liver disease. These benefits are particularly relevant for older adults and those with identified cardiovascular risks.

How it works

EVNol SupraBio primarily functions by modulating various cytosolic pathways, impacting neuronal survival and death mechanisms. It reduces activation of c-Src kinase, inhibits the phosphorylation of 12-lipoxygenase, and influences phospholipase A2 activity, thus promoting neuronal health. Additionally, it enhances cerebrovascular circulation and reduces cholesterol levels, promoting overall cardiovascular health. The high bioavailability of tocotrienols ensures their effective absorption and accumulation in essential organs, leading to positive health outcomes.

Side effects

Overall, EVNol SupraBio appears to be well-tolerated with a favorable safety profile when used appropriately. There is limited documentation on common adverse effects, but studies report low frequencies of side effects. Uncommon side effects have not been well-documented, while reports of rare side effects are absent. While no significant drug interactions are noted, individuals on multiple medications should exercise caution and consult healthcare providers. There are no specific contraindications, but pregnant or breastfeeding women are advised to seek medical advice due to insufficient data in these populations. Given its natural origin and antioxidant properties, EVNol SupraBio is generally considered safe.

Dosage

The recommended dosage for EVNol SupraBio ranges from 200-400 mg per day, as evidenced by various clinical studies. While a minimum effective dose is not firmly established, this range has shown to produce significant health benefits. There are no specific recommendations for timing; however, maintaining a consistent daily regimen is likely beneficial. The exact maximum safe dosage has not been thoroughly defined, though doses up to 400 mg have been employed without significant adverse effects. The form of EVNol SupraBio may vary, influencing bioavailability and effectiveness. A balanced diet may complement the supplement’s effects.

FAQs

Is EVNolmax safe for everyone?

While generally safe, individuals with underlying health issues or those taking medications should consult healthcare providers prior to use.

When is the best time to take EVNolmax?

There is no specific timing proven to enhance effectiveness; daily consistency is recommended.

What health benefits can I expect?

Potential benefits include enhanced brain health, reduced cardiovascular risks, and possible liver and kidney support.

Can EVNolmax replace my medication?

No, it is a supplement meant to provide additional support, not a replacement for prescribed medical treatments.

Research Sources

https://www.hpcimedia.com/images/PDF/EVNol_Excelvite.pdf – This document outlines various studies on EVNolmax, indicating its antioxidant properties and potential health benefits, including neuroprotection and cardiovascular support.
https://www.mdpi.com/2072-6643/15/15/3301 – This systematic review discusses tocotrienols' health effects, emphasizing their role in brain and cardiovascular health, and confirming their safety and bioavailability.