ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Fermented Eggshell Membrane Collagen

Also known as: Eggshell Membrane Collagen, Fermented Eggshell Membrane Collagen, Fermented Eggshell Membrane

Overview

Fermented Eggshell Membrane Collagen is a dietary supplement derived from the thin membrane lining eggshells. This membrane is naturally rich in various types of collagen (including types I, III, IV, V, VII, VIII, X, XII, and XXII) and other beneficial compounds such as chondroitin sulfate, glucosamine, and hyaluronic acid. The fermentation process is believed to enhance the bioavailability of these components. Primarily, it is used to support joint health, improve skin elasticity, and aid in exercise recovery. Research suggests potential benefits for reducing knee pain and stiffness associated with osteoarthritis, as well as improving skin firmness. It is available in various forms, including powders and capsules, and is generally considered safe for consumption.

Benefits

Eggshell membrane collagen has shown promise in several areas, particularly joint health. Clinical studies indicate that supplementation can significantly reduce knee pain and stiffness in individuals with osteoarthritis, leading to improvements in joint function and overall quality of life. Some studies have reported noticeable improvements in pain perception and WOMAC scores within a few weeks of consistent use. Additionally, there is evidence suggesting that eggshell membrane collagen may support skin health by improving elasticity and firmness. These benefits are primarily observed in individuals with knee osteoarthritis and those seeking to enhance their skin's appearance. While the evidence is generally positive, more rigorous systematic reviews are needed to fully validate these benefits across diverse populations and applications.

How it works

The mechanism of action for eggshell membrane collagen is thought to involve several biological pathways. The collagen and other compounds present in the membrane likely interact with joint tissues, helping to reduce inflammation and support cartilage health. The fermentation process is believed to enhance bioavailability by breaking down the collagen into smaller, more easily absorbed peptides. This improved absorption may lead to greater efficacy. Eggshell membrane collagen supports connective tissue health, including joints, skin, and potentially other tissues like hair and nails. While specific molecular targets are not yet fully identified, it likely interacts with collagen receptors and pathways involved in tissue repair and maintenance.

Side effects

Eggshell membrane collagen is generally considered safe for most individuals, with no major adverse effects reported in clinical studies. Common side effects are not well-documented, but are typically minimal. Uncommon and rare side effects have not been specifically reported in available research. No significant drug interactions have been identified. However, caution is advised for individuals with known allergies to egg products, as the supplement is derived from eggshells. Pregnant or breastfeeding women should consult with their healthcare providers before using eggshell membrane collagen. Overall, the safety profile is favorable, but individuals with specific health concerns should seek professional medical advice before starting supplementation.

Dosage

The typical recommended dosage of eggshell membrane collagen ranges from 300 to 500 mg per day. Studies have used doses within this range and have reported positive outcomes for joint health. While a maximum safe dose has not been definitively established, higher doses have not been associated with adverse effects in the available research. It can be taken at any time of day, but consistent daily use is recommended for optimal benefits. Eggshell membrane collagen is available in both powder and capsule forms. The fermentation process is believed to enhance absorption, potentially making fermented forms more bioavailable. No specific cofactors are required for its absorption or efficacy.

FAQs

Is eggshell membrane collagen safe for everyone?

It is generally safe for most adults. However, individuals with egg allergies should exercise caution due to its eggshell origin. Consulting with a healthcare provider is always recommended.

When is the best time to take eggshell membrane collagen?

It can be taken at any time of day. Consistency is key, so choose a time that fits easily into your daily routine to ensure regular use.

How long does it take to see results?

Improvements in joint health and skin elasticity may be noticeable within a few weeks of consistent use, according to some studies. Individual results may vary.

Where does eggshell membrane collagen come from?

It is derived from the thin membrane lining the inside of eggshells, not from the egg itself. This membrane is rich in collagen and other beneficial compounds.

Are there any known drug interactions?

No significant drug interactions have been reported in studies. However, always inform your healthcare provider about all supplements you are taking.

Research Sources

  • https://www.mdpi.com/2072-6643/16/16/2640 – This double-blind, parallel study investigated the effects of eggshell membrane supplementation on knee pain and functional capacity in osteoarthritis patients. The findings indicated that eggshell membrane significantly reduced knee pain and improved functional capacity in a dose-dependent manner, suggesting its potential as a therapeutic option for managing osteoarthritis symptoms.
  • https://ancientnutrition.com/blogs/all/eggshell-membrane-collagen – This article provides an overview of eggshell membrane collagen, highlighting its composition and potential benefits. It discusses the presence of various types of collagen and other beneficial compounds, emphasizing its role in supporting joint health and skin elasticity. While not a primary research article, it offers a useful summary of the supplement's properties.
  • https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2023.1116126/full – This study explores the use of eggshell membrane in veterinary science, specifically focusing on its potential benefits for animal health. The research suggests that eggshell membrane can be a valuable supplement for supporting joint health and overall well-being in animals, providing insights into its broader applications beyond human health.
  • https://pubmed.ncbi.nlm.nih.gov/38872992/ – This study investigates the impact of eggshell membrane supplementation on muscle damage and recovery following exercise. The results suggest that eggshell membrane may help reduce muscle damage and improve recovery after physical activity, indicating its potential benefits for athletes and individuals engaged in regular exercise.
  • https://www.researchgate.net/publication/383062360_Efficacy_of_Eggshell_Membrane_in_Knee_Osteoarthritis_A_Systematic_Review_and_Meta-Analysis – This systematic review and meta-analysis assesses the efficacy of eggshell membrane in treating knee osteoarthritis. The analysis of multiple studies provides a comprehensive overview of the evidence, helping to determine the overall effectiveness of eggshell membrane in reducing pain and improving function in individuals with knee osteoarthritis.

Supplements Containing Fermented Eggshell Membrane Collagen

Collagen Peptides Orange Flavor by Ancient Nutrition
68

Collagen Peptides Orange Flavor

Ancient Nutrition

Score: 68/100
Collagen Peptides Unflavored by Ancient Nutrition
82

Collagen Peptides Unflavored

Ancient Nutrition

Score: 82/100
Collagen Peptides Vanilla Flavor by Ancient Nutrition
92

Collagen Peptides Vanilla Flavor

Ancient Nutrition

Score: 92/100
Collagen Peptides by Ancient Nutrition
88

Collagen Peptides

Ancient Nutrition

Score: 88/100
Multi Collagen by Ancient Nutrition
85

Multi Collagen

Ancient Nutrition

Score: 85/100
Multi Collagen Brain Boost by Ancient Nutrition
75

Multi Collagen Brain Boost

Ancient Nutrition

Score: 75/100
Multi Collagen Joint + Mobility by Ancient Nutrition
75

Multi Collagen Joint + Mobility

Ancient Nutrition

Score: 75/100
Multi Collagen Protein by Ancient Nutrition
88

Multi Collagen Protein

Ancient Nutrition

Score: 88/100
Multi Collagen Protein by Ancient Nutrition
81

Multi Collagen Protein

Ancient Nutrition

Score: 81/100
Multi Collagen Protein by Ancient Nutrition
82

Multi Collagen Protein

Ancient Nutrition

Score: 82/100
Multi Collagen Protein Chocolate by Ancient Nutrition
70

Multi Collagen Protein Chocolate

Ancient Nutrition

Score: 70/100
Multi Collagen Protein Cucumber Lime by Ancient Nutrition
88

Multi Collagen Protein Cucumber Lime

Ancient Nutrition

Score: 88/100

Recommended Articles

Bone Health Supplements for Plant-Based Postmenopausal Women

Bone Health Supplements for Plant-Based Postmenopausal Women

Optimal bone health for postmenopausal individuals on plant-based diets involves calcium, vitamin D, magnesium, and vitamin K2 supplementation.

Key Nutrients for Bone Health & Osteoporosis Prevention

Key Nutrients for Bone Health & Osteoporosis Prevention

Critical nutrients for bone health include dietary protein, calcium, vitamin D, omega-3 fatty acids, and vitamin K2, alongside healthy lifestyle choices.

Top Ingredients for Optimal Gut Health

Top Ingredients for Optimal Gut Health

Fiber, probiotics, prebiotics, hydration, and fermented foods are crucial for maintaining healthy digestion and gut function.

Avoid These Food Combos for Better Health

Avoid These Food Combos for Better Health

Certain foods and supplements should not be consumed together due to interactions that can hinder nutrient absorption or pose health risks.