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Fortigel

Also known as: Bioactive Collagen Peptides, Fortigel®, Collagen Peptides, Specific Collagen Peptides (SCPs)

Overview

Fortigel® is a specific brand of bioactive collagen peptides (BCPs) derived from the hydrolysis of porcine type I collagen. It is primarily used as a nutritional supplement to support joint health, reduce joint pain and stiffness, and improve physical function. Fortigel® is characterized by a mean molecular weight of approximately 3 kDa, high solubility, and a specific amino acid profile. It is highly digestible, non-allergenic, and has a neutral odor and taste, making it easy to incorporate into various food products and supplements. Research on Fortigel® is mature, with multiple randomized controlled trials (RCTs) and observational studies demonstrating statistically significant and clinically relevant benefits for joint health. These studies highlight its potential to improve the quality of life for individuals experiencing joint pain and reduced mobility.

Benefits

Fortigel® has demonstrated several evidence-based benefits, primarily related to joint health. Studies have shown a statistically significant reduction in joint pain, with reductions in Visual Analog Scale (VAS) scores ranging from 28.5% to 49.4% over 3 months. Improvements in physical function have also been observed, as measured by the Lequesne algofunctional index (LAI) and the Western Ontario and McMaster Universities Index score (WOMAC). Furthermore, MRI studies suggest that Fortigel® may promote cartilage regeneration by increasing proteoglycan density in cartilage. These benefits have been observed in athletes, healthy adults experiencing activity-related joint pain, and individuals with mild-to-moderate osteoarthritis. The effects are typically observed as early as 3 weeks and continue to improve over 12 weeks, indicating a sustained benefit with continued use.

How it works

Fortigel® works by stimulating cartilage tissue metabolism and promoting the regeneration of cartilage. Its specific amino acid profile interacts with cellular mechanisms involved in cartilage repair and regeneration, leading to an increase in proteoglycan density. After ingestion, Fortigel® is highly soluble and absorbed intestinally, accumulating in cartilage tissue. This accumulation influences joint health by reducing inflammation and improving joint function. The bioactive peptides target chondrocytes, the cells responsible for maintaining cartilage, stimulating them to produce more collagen and proteoglycans, which are essential components of healthy cartilage.

Side effects

Fortigel® has a strong safety profile with no significant adverse events reported in clinical studies. Common, uncommon, and rare side effects have not been documented, indicating a low risk of adverse reactions. No known drug interactions or contraindications have been identified. Fortigel® is generally considered safe for use in various populations, including athletes and individuals with osteoarthritis. However, as with any supplement, it is advisable to consult a healthcare provider before use, especially for individuals with specific health conditions or allergies. The absence of reported side effects in multiple studies suggests that Fortigel® is well-tolerated, making it a safe option for individuals seeking to improve their joint health.

Dosage

The optimal dosage of Fortigel® appears to be around 10 g per day, as used in several studies demonstrating significant benefits. Studies have used doses ranging from 5 g to 10 g per day. No maximum safe dose has been established, but doses up to 10 g per day have been used without adverse effects. Fortigel® can be taken daily or every other day, with benefits observed regardless of the frequency. Due to its high solubility and neutral taste, Fortigel® can be easily incorporated into various food products and supplements. Its high solubility and intestinal absorption contribute to its effectiveness. No specific cofactors are required for its efficacy.

FAQs

Is Fortigel® safe to use?

Fortigel® is generally considered safe, with no significant adverse events reported in clinical studies. However, consulting a healthcare provider before use is always recommended.

How often should I take Fortigel®?

Fortigel® can be taken daily or every other day, depending on the study protocol. Consistency is key to experiencing its benefits.

How long before I see results?

Significant reductions in joint pain and improvements in physical function can be expected within a few weeks of consistent use.

Are there any known drug interactions?

No known drug interactions have been identified for Fortigel®. However, always inform your healthcare provider about all supplements you are taking.

What is Fortigel®?

Fortigel® is a specific brand of bioactive collagen peptides derived from the hydrolysis of porcine type I collagen, used to support joint health.

Research Sources

https://www.openaccessjournals.com/articles/randomized-observational-study-to-assess-the-efficacy-and-safety-of-the-association-of-fortigel-10-g-and-fucoidan-100-mg.pdf – This randomized observational multicenter study assessed the efficacy and safety of Fortigel® (10g) in 126 participants aged 40-65 years with mild-to-moderate osteoarthritis over 12 weeks. The study found significant reductions in VAS and LAI scores, indicating improved joint pain and functionality, suggesting that Fortigel® is effective in improving joint health.
https://www.researchgate.net/publication/311689868_Randomized_observational_multicenter_study_to_assess_the_efficacy_and_safety_of_the_association_of_Fortigel_10_Gr_and_Fucoidan_100_Mg_in_patients_with_Gonarthrosis – This randomized observational multicenter study evaluated the efficacy and safety of Fortigel® (10g) combined with Fucoidan (100mg) in patients with Gonarthrosis. The study reported significant improvements in joint pain and functionality, suggesting that Fortigel® may be beneficial for individuals with Gonarthrosis.
https://www.gelita.com/en/products/collagen-peptides/fortigel – This source from GELITA provides information on Fortigel®, highlighting its use in promoting cartilage regeneration and improving joint health. It emphasizes the bioactive collagen peptides' ability to stimulate cartilage metabolism and reduce joint pain, making it a valuable supplement for individuals with joint issues.
https://www.mdpi.com/1660-4601/21/6/687 – This study investigates the effects of collagen peptide supplementation on muscle strength and body composition. While not directly focused on Fortigel®, it provides insights into the broader benefits of collagen peptides, including potential improvements in muscle health, which can indirectly support joint function.
https://www.mdpi.com/2072-6643/15/9/2080 – This review article discusses the role of collagen peptides in sports nutrition and exercise physiology. It highlights the potential of collagen peptides, including Fortigel®, to support joint health, reduce exercise-related pain, and improve recovery, making it a relevant resource for understanding the benefits of Fortigel® in athletes.